Search Results - "Perez, Vinicio A de Jesus"

New and Emerging Therapies for Pulmonary Arterial Hypertension by Spiekerkoetter, Edda, Kawut, Steven M, de Jesus Perez, Vinicio A

“…Pulmonary arterial hypertension (PAH) is a pulmonary vasculopathy that causes right ventricular dysfunction and exercise limitation and progresses to death…”
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Beyond the Lungs: Systemic Manifestations of Pulmonary Arterial Hypertension by Nickel, Nils P, Yuan, Ke, Dorfmuller, Peter, Provencher, Steeve, Lai, Yen-Chun, Bonnet, Sebastien, Austin, Eric D, Koch, Carl D, Morris, Alison, Perros, Frédéric, Montani, David, Zamanian, Roham T, de Jesus Perez, Vinicio A

“…Pulmonary arterial hypertension (PAH) is a disease characterized by progressive loss and remodeling of the pulmonary arteries, resulting in right heart failure…”
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Emerging role of angiogenesis in adaptive and maladaptive right ventricular remodeling in pulmonary hypertension by Frump, Andrea L, Bonnet, Sébastien, de Jesus Perez, Vinicio A, Lahm, Tim

“…Right ventricular (RV) function is the primary prognostic factor for both morbidity and mortality in pulmonary hypertension (PH). RV hypertrophy is initially…”
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MiR-133a Modulates Osteogenic Differentiation of Vascular Smooth Muscle Cells by Liao, Xiao-Bo, Zhang, Zhi-Yuan, Yuan, Ke, Liu, Yuan, Feng, Xiang, Cui, Rong-Rong, Hu, Ye-Rong, Yuan, Zhao-Shun, Gu, Lu, Li, Shi-Jun, Mao, Ding-An, Lu, Qiong, Zhou, Xin-Ming, de Jesus Perez, Vinicio A, Yuan, Ling-Qing

“…Arterial calcification is a key pathologic component of vascular diseases such as atherosclerosis, coronary artery disease, and peripheral vascular disease. A…”
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BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways by Perez, Vinicio A. de Jesus, Ali, Ziad, Alastalo, Tero-Pekka, Ikeno, Fumiaki, Sawada, Hirofumi, Lai, Ying-Ju, Kleisli, Thomas, Spiekerkoetter, Edda, Qu, Xiumei, Rubinos, Laura H, Ashley, Euan, Amieva, Manuel, Dedhar, Shoukat, Rabinovitch, Marlene

“…We present a novel cell-signaling paradigm in which bone morphogenetic protein 2 (BMP-2) consecutively and interdependently activates the wingless…”
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In Defense of the Nucleus: NUDT1 and Oxidative DNA Damage in Pulmonary Arterial Hypertension by Agarwal, Stuti, de Jesus Perez, Vinicio A

“…Oxidative stress is an imbalance that favors the production and accumulation of reactive oxygen species (ROS) over antioxidants, resulting in organelle…”
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Long Noncoding RNA TYKRIL Plays a Role in Pulmonary Hypertension via the p53-mediated Regulation of PDGFRβ by Zehendner, Christoph M, Valasarajan, Chanil, Werner, Astrid, Boeckel, Jes-Niels, Bischoff, Florian C, John, David, Weirick, Tyler, Glaser, Simone F, Rossbach, Oliver, Jaé, Nicolas, Demolli, Shemsi, Khassafi, Fatemeh, Yuan, Ke, de Jesus Perez, Vinicio A, Michalik, Katharina M, Chen, Wei, Seeger, Werner, Guenther, Andreas, Wasnick, Roxana M, Uchida, Shizuka, Zeiher, Andreas M, Dimmeler, Stefanie, Pullamsetti, Soni S

“…Long noncoding RNAs (lncRNAs) are emerging as important regulators of diverse biological functions. Their role in pulmonary arterial hypertension (PAH) remains…”
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The cancer hypothesis of pulmonary arterial hypertension: the next ten years by Condon, David, Agarwal, Stuti, Chakraborty, Ananya, de Jesus Perez, Vinicio A

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Mural Cell SDF1 Signaling Is Associated with the Pathogenesis of Pulmonary Arterial Hypertension by Yuan, Ke, Liu, Yu, Zhang, Yue, Nathan, Abinaya, Tian, Wen, Yu, Joyce, Sweatt, Andrew J, Shamshou, Elya A, Condon, David, Chakraborty, Ananya, Agarwal, Stuti, Auer, Natasha, Zhang, Serena, Wu, Joseph C, Zamanian, Roham T, Nicolls, Mark R, de Jesus Perez, Vinicio A

“…Pulmonary artery smooth muscle cells (PASMCs) and pericytes are NG2 mural cells that provide structural support to pulmonary arteries and capillaries. In…”
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Cholinergic modulation of angiogenesis: Role of the 7 nicotinic acetylcholine receptor by Wu, Jenny C.F., Chruscinski, Andrzej, De Jesus Perez, Vinicio A., Singh, Harvir, Pitsiouni, Maria, Rabinovitch, Marlene, Utz, Paul J., Cooke, John P.

“…Pathological angiogenesis contributes to tobacco‐related diseases such as malignancy, atherosclerosis and age‐related macular degeneration. Nicotine acts on…”
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The 6th World Symposium on Pulmonary Hypertension: what's old is new [version 1; peer review: 3 approved] by Condon, David F, Nickel, Nils P, Anderson, Ryan, Mirza, Shireen, de Jesus Perez, Vinicio A

“…In February 2018, the 6th World Symposium on Pulmonary Hypertension (WSPH) brought together experts from various disciplines to review the most relevant…”
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EpiHope for the Treatment of Pulmonary Arterial Hypertension: Selective versus Nonselective BET Inhibition by Pullamsetti, Soni Savai, de Jesus Perez, Vinicio A

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Access to Medically Necessary Reproductive Care for Individuals with Pulmonary Hypertension by Sonntag, Elizabeth, Akgün, Kathleen M, Bag, Remzi, Rosensweig, Erika B, Bernardo, Roberto J, Burnetti, Colleen, Chybowski, Amy, de Jesus Perez, Vinicio A, Diwan, Johnell, Guthrie, Kate M, Halscott, Torre, Lahm, Tim, Vaught, Jason, Ventetuolo, Corey E, Hemnes, Anna R

“…Pulmonary arterial hypertension (PAH) disproportionately affects young females and is associated with poor survival rates. Access to comprehensive reproductive…”
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Interleukin‐10–mediated regenerative postnatal tissue repair is dependent on regulation of hyaluronan metabolism via fibroblast‐specific STAT3 signaling by Balaji, Swathi, Wang, Xinyi, King, Alice, Le, Louis D., Bhattacharya, Sukanta S., Moles, Chad M., Butte, Manish J., Jesus Perez, Vinicio A., Liechty, Kenneth W., Wight, Thomas N., Crombleholme, Timothy M., Bollyky, Paul L., Keswani, Sundeep G.

“…ABSTRACT The cytokine IL‐10 has potent antifibrotic effects in models of adult fibrosis, but the mechanisms of action are unclear. Here, we report a novel…”
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An evidence appraisal of heart organoids in a dish and commensurability to human heart development in vivo by Thomas, Dilip, de Jesus Perez, Vinicio A, Sayed, Nazish

“…Stem-cell derived in vitro cardiac models have provided profound insights into mechanisms in cardiac development and disease. Efficient differentiation of…”
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Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension by Orcholski, Mark E, Khurshudyan, Artyom, Shamskhou, Elya A, Yuan, Ke, Chen, Ian Y, Kodani, Sean D, Morisseau, Christophe, Hammock, Bruce D, Hong, Ellen M, Alexandrova, Ludmila, Alastalo, Tero-Pekka, Berry, Gerald, Zamanian, Roham T, de Jesus Perez, Vinicio A

“…Pulmonary arterial hypertension is a complication of methamphetamine use (METH-PAH), but the pathogenic mechanisms are unknown. Given that cytochrome P450 2D6…”
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Low-grade albuminuria in pulmonary arterial hypertension by Nickel, Nils P., de Jesus Perez, Vinicio A., Zamanian, Roham T., Fessel, Joshua P., Cogan, Joy D., Hamid, Rizwam, West, James D., de Caestecker, Mark P., Yang, Haichun, Austin, Eric D.

“…Low-grade albuminuria, determined by the urinary albumin to creatinine ratio, has been linked to systemic vascular dysfunction and is associated with…”
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Suppression of endothelial CD39/ENTPD1 is associated with pulmonary vascular remodeling in pulmonary arterial hypertension by Helenius, Mikko H, Vattulainen, Sanna, Orcholski, Mark, Aho, Joonas, Komulainen, Anne, Taimen, Pekka, Wang, Lingli, de Jesus Perez, Vinicio A, Koskenvuo, Juha W, Alastalo, Tero-Pekka

“…Endothelial cell (EC) dysfunction plays a role in the pathobiology of occlusive vasculopathy in pulmonary arterial hypertension (PAH). Purinergic signaling…”
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First among Equals: Nerve Growth Factor in the Pathogenesis of Pulmonary Arterial Hypertension by de Jesus Perez, Vinicio A

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Pumping it up! Angiogenesis and muscle deconditioning in pulmonary hypertension by de Jesus Perez, Vinicio A

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