Search Results - "Perez, Itxaro"
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Expression and activity of angiotensin-regulating enzymes is associated with prognostic outcome in clear cell renal cell carcinoma patients
Published in PloS one (15-08-2017)“…The discovery of the intrarenal renin-angiotensin system (iRAS), which regulates angiogenesis, cell differentiation and proliferation, has opened new…”
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Dipeptidyl-peptidase IV activity is correlated with colorectal cancer prognosis
Published in PloS one (19-03-2015)“…Dipeptidyl-peptidase IV (EC 3.4.14.5) (DPPIV) is a serine peptidase involved in cell differentiation, adhesion, immune modulation and apoptosis, functions that…”
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The impact of peptidase activity on clear cell renal cell carcinoma survival
Published in American journal of physiology. Renal physiology (15-12-2012)“…Several studies have proposed that protease expression and activity may have a predictive value in the survival of clear cell renal cell carcinoma (CCRCC)…”
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Expression and activity profiles of DPP IV/CD26 and NEP/CD10 glycoproteins in the human renal cancer are tumor-type dependent
Published in BMC cancer (11-05-2010)“…Cell-surface glycoproteins play critical roles in cell-to-cell recognition, signal transduction and regulation, thus being crucial in cell proliferation and…”
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Cannabinoid CB1 Receptor Is Downregulated in Clear Cell Renal Cell Carcinoma
Published in The journal of histochemistry and cytochemistry (01-12-2010)“…Several studies in cell cultures and in animal models have demonstrated that cannabinoids have important antitumoral properties. Because many of these effects…”
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Expression of cannabinoid receptors in human kidney
Published in Histology and histopathology (01-09-2010)“…The presence of CB1 and CB2 cannabinoid receptors and their physiological role in the kidney has been described in animal models but not in humans. Our aim in…”
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Increased APN/CD13 and acid aminopeptidase activities in head and neck squamous cell carcinoma
Published in Head & neck (01-10-2009)“…Background. Involvement of peptidases in carcinogenic processes of several tumor types has been investigated in recent years. Head and neck squamous cell…”
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Angiotensin-converting enzymes (ACE and ACE2) are downregulated in renal tumors
Published in Regulatory peptides (10-12-2010)“…The angiotensin-converting enzymes (ACE and ACE2) are highly expressed in renal tubules and play an important role in the regulation of renal function by the…”
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Acid, basic, and neutral peptidases present different profiles in chromophobe renal cell carcinoma and in oncocytoma
Published in American journal of physiology. Renal physiology (01-04-2008)“…Renal cell carcinomas (RCCs) are neoplasias with high prevalence and mortality. We previously reported that several peptidases may be involved in the…”
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Altered dipeptidyl peptidase IV and prolyl endopeptidase activities in chronic tonsillitis, tonsillar hyperplasia and adenoid hyperplasia
Published in International journal of pediatric otorhinolaryngology (01-03-2011)“…Abstract Objective To analyse peptidase activities in the removed tonsils and adenoids from patients with chronic tonsillitis, tonsillar hyperplasia and…”
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Aminopeptidase N Activity Predicts 5-Year Survival in Colorectal Cancer Patients
Published in Journal of investigative medicine (01-06-2015)“…BackgroundAminopeptidase N (APN; EC 3.4.11.2) is a membrane dimeric metallopeptidase involved in differentiation, development, and proliferative processes of…”
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Increased prolyl endopeptidase activity in human neoplasia
Published in Regulatory peptides (09-08-2010)“…Prolyl endopeptidase (EC 3.4.21.26) (PEP) is a serine peptidase that converts several biologically active peptides. This enzyme has been linked to several…”
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13
Clinical impact of aspartyl aminopeptidase expression and activity in colorectal cancer
Published in Translational research : the journal of laboratory and clinical medicine (01-11-2013)“…Aspartyl aminopeptidase (ASP; EC 3.4.11.21) is a widely distributed and abundant cytosolic enzyme that regulates bioactive peptides such as angiotensin II. It…”
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14
Cannabinoid CB1 receptor is expressed in chromophobe renal cell carcinoma and renal oncocytoma
Published in Clinical biochemistry (01-05-2013)“…To analyze the mRNA and protein expression of cannabinoid receptors CB1 and CB2 in chromophobe renal cell carcinoma (ChRCC) and renal oncocytoma (RO). Fresh…”
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Altered glutamyl-aminopeptidase activity and expression in renal neoplasms
Published in BMC cancer (30-05-2014)“…Advances in the knowledge of renal neoplasms have demonstrated the implication of several proteases in their genesis, growth and dissemination…”
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16
Altered Peptidase Activities in Thyroid Neoplasia and Hyperplasia
Published in Disease markers (01-01-2013)“…Papillary thyroid carcinoma (PTC), follicular thyroid adenoma (FTA), and thyroid nodular hyperplasia (TNH) are the most frequent diseases of the thyroid gland…”
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Changes in Cell-Surface Peptidase Activity in Papillary Renal Cell Carcinoma
Published in Anticancer research (01-04-2010)“…Renal cancer is one of the ten most common malignant tumours in humans and its histological classification, best clinical management and treatment strategies…”
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Erratum to “Activity of soluble aminopeptidase A and dipeptidyl peptidase IV and membrane-bound aminopeptidase B and pyroglutamyl peptidase I in adenoid hyperplasia, tonsillar hyperplasia and chronic tonsillitis” [Int. J. Pediatr. Otorhinolaryngol. 75 (November (11)) (2011) 1399–1403]
Published in International journal of pediatric otorhinolaryngology (01-02-2012)Get full text
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Activity of soluble aminopeptidase A and dipeptidyl peptidase IV and membrane-bound aminopeptidase B and pyroglutamyl peptidase I in adenoid hyperplasia, tonsillar hyperplasia and chronic tonsillitis
Published in International journal of pediatric otorhinolaryngology (01-11-2011)“…Abstract Objective To analyze soluble and membrane-bound peptidase activities in the tonsils and adenoids removed from patients with adenoid hyperplasia,…”
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Altered expression of renin-angiotensin system receptors throughout colorectal adenoma-adenocarcinoma sequence
Published in International journal of medical sciences (01-01-2019)“…: Colorectal cancer (CRC) is a major health problem in developed countries. Adenomatous lesions in the large bowel are the main precursors of CRC and the…”
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