Search Results - "Perez, Itxaro"

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  1. 1

    Expression and activity of angiotensin-regulating enzymes is associated with prognostic outcome in clear cell renal cell carcinoma patients by Errarte, Peio, Beitia, Maider, Perez, Itxaro, Manterola, Lorea, Lawrie, Charles H, Solano-Iturri, Jon Danel, Calvete-Candenas, Julio, Unda, Miguel, López, José I, Larrinaga, Gorka

    Published in PloS one (15-08-2017)
    “…The discovery of the intrarenal renin-angiotensin system (iRAS), which regulates angiogenesis, cell differentiation and proliferation, has opened new…”
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  2. 2

    Dipeptidyl-peptidase IV activity is correlated with colorectal cancer prognosis by Larrinaga, Gorka, Perez, Itxaro, Sanz, Begoña, Beitia, Maider, Errarte, Peio, Fernández, Ainhoa, Blanco, Lorena, Etxezarraga, María C, Gil, Javier, López, José I

    Published in PloS one (19-03-2015)
    “…Dipeptidyl-peptidase IV (EC 3.4.14.5) (DPPIV) is a serine peptidase involved in cell differentiation, adhesion, immune modulation and apoptosis, functions that…”
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  3. 3

    The impact of peptidase activity on clear cell renal cell carcinoma survival by Larrinaga, Gorka, Blanco, Lorena, Sanz, Begoña, Perez, Itxaro, Gil, Javier, Unda, Miguel, Andrés, Leire, Casis, Luis, López, José I

    “…Several studies have proposed that protease expression and activity may have a predictive value in the survival of clear cell renal cell carcinoma (CCRCC)…”
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  4. 4

    Expression and activity profiles of DPP IV/CD26 and NEP/CD10 glycoproteins in the human renal cancer are tumor-type dependent by Varona, Adolfo, Blanco, Lorena, Perez, Itxaro, Gil, Javier, Irazusta, Jon, López, José I, Candenas, M Luz, Pinto, Francisco M, Larrinaga, Gorka

    Published in BMC cancer (11-05-2010)
    “…Cell-surface glycoproteins play critical roles in cell-to-cell recognition, signal transduction and regulation, thus being crucial in cell proliferation and…”
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  5. 5

    Cannabinoid CB1 Receptor Is Downregulated in Clear Cell Renal Cell Carcinoma by Larrinaga, Gorka, Begoña, Sanz, Itxaro, Pérez, Blanco, Lorena, Maria, L. Cándenas, Pinto, Francisco M., Gil, Javier, José, I. López

    “…Several studies in cell cultures and in animal models have demonstrated that cannabinoids have important antitumoral properties. Because many of these effects…”
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  6. 6

    Expression of cannabinoid receptors in human kidney by Larrinaga, Gorka, Varona, Adolfo, Pérez, Itxaro, Sanz, Begoña, Ugalde, Aitziber, Cándenas, M Luz, Pinto, Francisco M, Gil, Javier, López, José I

    Published in Histology and histopathology (01-09-2010)
    “…The presence of CB1 and CB2 cannabinoid receptors and their physiological role in the kidney has been described in animal models but not in humans. Our aim in…”
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  7. 7

    Increased APN/CD13 and acid aminopeptidase activities in head and neck squamous cell carcinoma by Pérez, Itxaro, Varona, Adolfo, Blanco, Lorena, Gil, Javier, Santaolalla, Francisco, Zabala, Aitor, Ibarguen, Agustin Martínez, Irazusta, Jon, Larrinaga, Gorka

    Published in Head & neck (01-10-2009)
    “…Background. Involvement of peptidases in carcinogenic processes of several tumor types has been investigated in recent years. Head and neck squamous cell…”
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  8. 8

    Angiotensin-converting enzymes (ACE and ACE2) are downregulated in renal tumors by Larrinaga, Gorka, Pérez, Itxaro, Sanz, Begoña, Blanco, Lorena, López, Jose I., Cándenas, M. Luz, Pinto, Francisco M., Gil, Javier, Irazusta, Jon, Varona, Adolfo

    Published in Regulatory peptides (10-12-2010)
    “…The angiotensin-converting enzymes (ACE and ACE2) are highly expressed in renal tubules and play an important role in the regulation of renal function by the…”
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  9. 9

    Acid, basic, and neutral peptidases present different profiles in chromophobe renal cell carcinoma and in oncocytoma by Blanco, Lorena, Larrinaga, Gorka, Pérez, Itxaro, López, José I, Gil, Javier, Agirregoitia, Ekaitz, Varona, Adolfo

    “…Renal cell carcinomas (RCCs) are neoplasias with high prevalence and mortality. We previously reported that several peptidases may be involved in the…”
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  10. 10

    Altered dipeptidyl peptidase IV and prolyl endopeptidase activities in chronic tonsillitis, tonsillar hyperplasia and adenoid hyperplasia by Larrinaga, Gorka, Pérez, Itxaro, Sanz, Begoña, Zarrazquin, Idoia, Casis, Luis, Anta, Jose Antonio, Martínez, Agustin, Santaolalla, Francisco

    “…Abstract Objective To analyse peptidase activities in the removed tonsils and adenoids from patients with chronic tonsillitis, tonsillar hyperplasia and…”
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  11. 11

    Aminopeptidase N Activity Predicts 5-Year Survival in Colorectal Cancer Patients by Sanz, Begoña, Perez, Itxaro, Beitia, Maider, Errarte, Peio, Fernández, Ainhoa, Blanco, Lorena, Estalella, Itziar, Loizate, Alberto, Irazusta, Jon, López, José I., Larrinaga, Gorka

    Published in Journal of investigative medicine (01-06-2015)
    “…BackgroundAminopeptidase N (APN; EC 3.4.11.2) is a membrane dimeric metallopeptidase involved in differentiation, development, and proliferative processes of…”
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  12. 12

    Increased prolyl endopeptidase activity in human neoplasia by Larrinaga, Gorka, Perez, Itxaro, Blanco, Lorena, López, José I., Andrés, Leire, Etxezarraga, Carmen, Santaolalla, Francisco, Zabala, Aitor, Varona, Adolfo, Irazusta, Jon

    Published in Regulatory peptides (09-08-2010)
    “…Prolyl endopeptidase (EC 3.4.21.26) (PEP) is a serine peptidase that converts several biologically active peptides. This enzyme has been linked to several…”
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  13. 13

    Clinical impact of aspartyl aminopeptidase expression and activity in colorectal cancer by Larrinaga, Gorka, Perez, Itxaro, Ariz, Usue, Sanz, Begoña, Beitia, Maider, Errarte, Peio, Etxezarraga, Carmen, Candenas, M. Luz, Pinto, Francisco M, López, José I

    “…Aspartyl aminopeptidase (ASP; EC 3.4.11.21) is a widely distributed and abundant cytosolic enzyme that regulates bioactive peptides such as angiotensin II. It…”
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  14. 14

    Cannabinoid CB1 receptor is expressed in chromophobe renal cell carcinoma and renal oncocytoma by Larrinaga, Gorka, Sanz, Begoña, Blanco, Lorena, Perez, Itxaro, Candenas, María L., Pinto, Francisco M., Irazusta, Amaia, Gil, Javier, López, José I.

    Published in Clinical biochemistry (01-05-2013)
    “…To analyze the mRNA and protein expression of cannabinoid receptors CB1 and CB2 in chromophobe renal cell carcinoma (ChRCC) and renal oncocytoma (RO). Fresh…”
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  15. 15

    Altered glutamyl-aminopeptidase activity and expression in renal neoplasms by Blanco, Lorena, Sanz, Begoña, Perez, Itxaro, Sánchez, Clara E, Cándenas, M Luz, Pinto, Francisco M, Gil, Javier, Casis, Luis, López, José I, Larrinaga, Gorka

    Published in BMC cancer (30-05-2014)
    “…Advances in the knowledge of renal neoplasms have demonstrated the implication of several proteases in their genesis, growth and dissemination…”
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  16. 16

    Altered Peptidase Activities in Thyroid Neoplasia and Hyperplasia by Andrés, Leire, López, José I., Santaolalla, Francisco, Irazusta, Amaia, Perez, Itxaro, Sanz, Begoña, Beitia, Maider, Errarte, Peio, Blanco, Lorena, Larrinaga, Gorka, Sánchez, Clara E.

    Published in Disease markers (01-01-2013)
    “…Papillary thyroid carcinoma (PTC), follicular thyroid adenoma (FTA), and thyroid nodular hyperplasia (TNH) are the most frequent diseases of the thyroid gland…”
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  17. 17

    Changes in Cell-Surface Peptidase Activity in Papillary Renal Cell Carcinoma by BLANCO, Lorena, PEREZ, Itxaro, SANZ, Begona, GIL, Javier, LOPEZ, José I, UGALDE, Aitziber, VARONA, Adolfo, LARRINAGA, Gorka

    Published in Anticancer research (01-04-2010)
    “…Renal cancer is one of the ten most common malignant tumours in humans and its histological classification, best clinical management and treatment strategies…”
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    Altered expression of renin-angiotensin system receptors throughout colorectal adenoma-adenocarcinoma sequence by Beitia, Maider, Solano-Iturri, Jon Danel, Errarte, Peio, Sanz, Begoña, Perez, Itxaro, Etxezarraga, María C, Loizate, Alberto, Asumendi, Aintzane, Larrinaga, Gorka

    Published in International journal of medical sciences (01-01-2019)
    “…: Colorectal cancer (CRC) is a major health problem in developed countries. Adenomatous lesions in the large bowel are the main precursors of CRC and the…”
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