Search Results - "Perez, H.Daniel"

Species selectivity of a small molecule antagonist for the CCR1 chemokine receptor by Liang, Meina, Rosser, Mary, Ng, Howard P, May, Karen, Bauman, John G, Islam, Imadul, Ghannam, Ameen, Kretschmer, Peter J, Pu, Haifeng, Dunning, Laura, Snider, R.Michael, Morrissey, Michael M, Hesselgesser, Joseph, Perez, H.Daniel, Horuk, Richard

“…The species specificity of a small molecule antagonist for the human CCR1 chemokine receptor, 2-2-diphenyl-5-(4-chlorophenyl)piperidin-1-yl)valeronitrile (CCR1…”
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Induction of RANTES expression by astrocytes and astrocytoma cell lines by Barnes, Debra A., Huston, Michael, Holmes, Richard, Benveniste, Etty N., Yong, V.Wee, Scholz, Peter, Perez, H.Daniel

“…The cellular infiltrate found during the acute phase of multiple sclerosis (MS) consists of monocytes and activated T cells, suggesting the presence of…”
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Cloning of a cDNA encoding a receptor related to the formyl peptide receptor of human neutrophils by Perez, H D, Holmes, R, Kelly, E, McClary, J, Andrews, W H

“…We cloned a cDNA (RFP) encoding a receptor (RFP) related (70% overall nucleotide homology) to the formyl peptide receptor of human neutrophils (hFPR). RFP is a…”
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Pulmonary hypertension in systemic lupus erythematosus: report of four cases and review of the literature by Perez, H D, Kramer, N

“…Pulmonary hypertension has been reported rarely in patients with systemic lupus erythematosus (SLE). During the past 31/2 yr we have observed pulmonary…”
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Identification and Characterization of a Potent, Selective, and Orally Active Antagonist of the CC Chemokine Receptor-1 by Liang, Meina, Mallari, Cornell, Rosser, Mary, Ng, Howard P., May, Karen, Monahan, Sean, Bauman, John G., Islam, Imadul, Ghannam, Ameen, Buckman, Brad, Shaw, Ken, Wei, Guo-Ping, Xu, Wei, Zhao, Zuchun, Ho, Elena, Shen, Jun, Oanh, Huynh, Subramanyam, Babu, Vergona, Ron, Taub, Dennis, Dunning, Laura, Harvey, Susan, Snider, R.Michael, Hesselgesser, Joseph, Morrissey, Michael M., Perez, H.Daniel, Horuk, Richard

“…The CC chemokine receptor-1 (CCR1) is a prime therapeutic target for treating autoimmune diseases. Through high capacity screening followed by chemical…”
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CCR1-specific non-peptide antagonist: efficacy in a rabbit allograft rejection model by Horuk, Richard, Shurey, Sandra, Ng, Howard P, May, Karen, Bauman, John G, Islam, Imadul, Ghannam, Ameen, Buckman, Brad, Wei, Guo Ping, Xu, Wei, Liang, Meina, Rosser, Mary, Dunning, Laura, Hesselgesser, Joseph, Snider, R.Michael, Morrissey, Michael M, Perez, H.Daniel, Green, Colin

“…The classic signs of acute cellular rejection during organ transplantation include the infiltration of mononuclear cells into the interstitium. This…”
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The type IV phosphodiesterase specific inhibitor mesopram inhibits experimental autoimmune encephalomyelitis in rodents by Dinter, Harald, Tse, Jenny, Halks-Miller, Meredith, Asarnow, David, Onuffer, James, Faulds, Daryl, Mitrovic, Branislava, Kirsch, Gerald, Laurent, Henry, Esperling, Peter, Seidelmann, Dieter, Ottow, Eckhard, Schneider, Herbert, Tuohy, Vincent K, Wachtel, Helmut, Perez, H.Daniel

“…Experimental autoimmune encephalomyelitis (EAE) is an autoimmune disease with pathological features reminiscent of those seen in multiple sclerosis and thus…”
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Formation of a Uniquely Stable Type I Interferon Receptor Complex by Interferon β Is Dependent upon Particular Interactions between Interferon β and Its Receptor and Independent of Tyrosine Phosphorylation by Russell-Harde, Dean, Wagner, T.Charis, Perez, H.Daniel, Croze, Ed

“…Human type I interferons (IFN) require two receptor chains, IFNAR1 and IFNAR2c for high affinity (pM) binding and biological activity. Our previous studies…”
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Interleukin-1β induction of the chemokine RANTES promoter in the human astrocytoma line CH235 requires both constitutive and inducible transcription factors by Miyamoto, Neil G., Medberry, Poonam S., Hesselgesser, Joe, Boehlk, Sabine, Nelson, Peter J., Krensky, Alan M., Perez, H.Daniel

“…The chemokine RANTES is an important mediator of inflammatory processes. In this report, we describe the DNA sequence and transcription factor requirements for…”
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TNF- α and IL-1 β cross-desensitization of astrocytes and astrocytoma cell lines by Barnes, Debra A, Huston, Michael, Perez, H.Daniel

“…Exposure of human astrocytes and astrocytoma cell lines to TNF- α, IL-1 β and γIFN induce expression of a specific member of the intercrine/chemokine family of…”
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High throughput screening for identification of RANTES chemokine expression inhibitors by Barnes, D A, Jones, S W, Perez, H D

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Metabolism of ethanol by rat hepatocytes results in generation of a lipid chemotactic factor: studies using a cell-free system and role of oxygen-derived free radicals by Roll, F J, Alexander, M A, Cua, D, Swanson, W, Perez, H D

“…We have reported that liver cells metabolizing ethanol release a lipid that has chemotactic activity for human polymorphonuclear leukocytes. The purpose of the…”
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Effect of phorbol myristate acetate on processing of formyl peptide receptors by human neutrophils by Lobo, E, Elfman, F, Kelly, E, Perez, H D

“…We examined the effect of phorbol myristate acetate on the ability of human neutrophils to process formyl peptide receptors. The receptor was affinity-labeled…”
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Human hepatocytes metabolizing ethanol generate a non-polar chemotactic factor for human neutrophils by Roll, F J, Bissell, D M, Perez, H D

“…When human hepatocytes were incubated with low concentrations of ethanol they general chemotactic activity for human neutrophils. Generation of chemotactic…”
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Human neutrophils contain subpopulations of specific granules exhibiting different sensitivities to changes in cytosolic free calcium by Perez, H D, Marder, S, Elfman, F, Ives, H E

“…We examined the role of mobilization of intracellular calcium in the ability of human neutrophils to discharge specific granule constituents upon stimulation…”
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Radioimmunoelectrophoresis, a sensitive method for detecting cleavage of the fifth component of human complement (C5) by Perez, H D, Ong, R, Banda, D, Goldstein, I M

“…A method has been developed for detecting cleavage of human C5 in serum and whole blood as a consequence of complement activation. Standard, single-dimension…”
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Chemotactic activity of C5ades Arg: evidence of a requirement for an anionic peptide 'helper factor' and inhibition by a cationic protein in serum from patients with systemic lupus erythematosus by Perez, H D, Goldstein, I M, Chernoff, D, Webster, R O, Henson, P M

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Reversal of an abnormality of polymorphonuclear leukocyte chemotaxis with lithium by Perez, H D, Kaplan, H B, Goldstein, I M, Shenkman, L, Borkowsky, W

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