Search Results - "Perez, Eilís"
-
1
-
2
DNA methylation classifier to diagnose pancreatic ductal adenocarcinoma metastases from different anatomical sites
Published in Clinical epigenetics (10-11-2024)“…Abstract Background We have recently constructed a DNA methylation classifier that can discriminate between pancreatic ductal adenocarcinoma (PAAD) liver…”
Get full text
Journal Article -
3
High-grade astrocytoma with piloid features (HGAP): the Charité experience with a new central nervous system tumor entity
Published in Journal of neuro-oncology (01-05-2021)“…Purpose High-grade astrocytoma with piloid features (HGAP) is a recently described brain tumor entity defined by a specific DNA methylation profile. HGAP has…”
Get full text
Journal Article -
4
Conumee 2.0: enhanced copy-number variation analysis from DNA methylation arrays for humans and mice
Published in Bioinformatics (Oxford, England) (01-02-2024)“…Abstract Motivation Copy-number variations (CNVs) are common genetic alterations in cancer and their detection may impact tumor classification and therapeutic…”
Get full text
Journal Article -
5
Diffuse paediatric-type high-grade glioma, H3-wildtype and IDH-wildtype: case series of a new entity
Published in Brain tumor pathology (01-10-2023)“…Diffuse paediatric-type high-grade glioma, H3-wildtype and IDH-wildtype (pHGG) is a rare and aggressive brain tumor characterized by a specific DNA methylation…”
Get full text
Journal Article -
6
Adult intracranial ependymoma—relevance of DNA methylation profiling for diagnosis, prognosis, and treatment
Published in Neuro-oncology (Charlottesville, Va.) (06-07-2023)“…Abstract Background A methylation-based classification of ependymoma has recently found broad application. However, the diagnostic advantage and implications…”
Get full text
Journal Article -
7
Clinical implications of DNA methylation-based integrated classification of histologically defined grade 2 meningiomas
Published in Acta neuropathologica communications (08-05-2024)“…The combination of DNA methylation analysis with histopathological and genetic features allows for a more accurate risk stratification and classification of…”
Get full text
Journal Article -
8
Sarcoma classification by DNA methylation profiling in clinical everyday life: the Charité experience
Published in Clinical epigenetics (15-11-2022)“…Sarcomas are a heterogeneous group of rare malignant tumors with more than 100 subtypes. Accurate diagnosis remains challenging due to a lack of characteristic…”
Get full text
Journal Article -
9
DNA methylation‐array interlaboratory comparison trial demonstrates highly reproducible paediatric CNS tumour classification across 13 international centres
Published in Neuropathology and applied neurobiology (01-10-2024)“…Aims DNA methylation profiling, recently endorsed by the World Health Organisation (WHO) as a pivotal diagnostic tool for brain tumours, most commonly relies…”
Get full text
Journal Article -
10
DNA methylation-based classifier differentiates intrahepatic pancreato-biliary tumours
Published in EBioMedicine (01-07-2023)“…Differentiating intrahepatic cholangiocarcinomas (iCCA) from hepatic metastases of pancreatic ductal adenocarcinoma (PAAD) is challenging. Both tumours have…”
Get full text
Journal Article -
11
Abstract 4414: Genome-wide DNA methylation classifier diagnoses pancreatic ductal adenocarcinoma in CUP setting
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Introduction: The metastasis of a pancreatic ductal adenocarcinoma (PAAD) is a diagnosis of exclusion and one of the most common causes of cancer of…”
Get full text
Journal Article -
12
DNA methylation-based classifier differentiates intrahepatic pancreato-biliary tumoursResearch in context
Published in EBioMedicine (01-07-2023)“…Background: Differentiating intrahepatic cholangiocarcinomas (iCCA) from hepatic metastases of pancreatic ductal adenocarcinoma (PAAD) is challenging. Both…”
Get full text
Journal Article -
13
A Novel Type of IDH-wildtype Glioma Characterized by Gliomatosis Cerebri-like Growth Pattern, TERT Promoter Mutation, and Distinct Epigenetic Profile
Published in The American journal of surgical pathology (01-12-2023)“…Diffuse gliomas in adults encompass a heterogenous group of central nervous system neoplasms. In recent years, extensive (epi-)genomic profiling has identified…”
Get full text
Journal Article -
14
Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with neurofibromatosis type 1
Published in Acta neuropathologica (01-01-2023)“…High-grade astrocytoma with piloid features (HGAP) is a recently recognized glioma type whose classification is dependent on its global epigenetic signature…”
Get full text
Journal Article -
15
Genetic and epigenetic characterization of posterior pituitary tumors
Published in Acta neuropathologica (01-12-2021)“…Pituicytoma (PITUI), granular cell tumor (GCT), and spindle cell oncocytoma (SCO) are rare tumors of the posterior pituitary. Histologically, they may be…”
Get full text
Journal Article