Search Results - "Perevoshchikova, Irina V."

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions by Quinlan, Casey L., Orr, Adam L., Perevoshchikova, Irina V., Treberg, Jason R., Ackrell, Brian A., Brand, Martin D.

“…Respiratory complex II oxidizes succinate to fumarate as part of the Krebs cycle and reduces ubiquinone in the electron transport chain. Previous experimental…”
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Sites of Superoxide and Hydrogen Peroxide Production by Muscle Mitochondria Assessed ex Vivo under Conditions Mimicking Rest and Exercise by Goncalves, Renata L.S., Quinlan, Casey L., Perevoshchikova, Irina V., Hey-Mogensen, Martin, Brand, Martin D.

“…The sites and rates of mitochondrial production of superoxide and H2O2in vivo are not yet defined. At least 10 different mitochondrial sites can generate these…”
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A Refined Analysis of Superoxide Production by Mitochondrial sn-Glycerol 3-Phosphate Dehydrogenase by Orr, Adam L., Quinlan, Casey L., Perevoshchikova, Irina V., Brand, Martin D.

“…The oxidation of sn-glycerol 3-phosphate by mitochondrial sn-glycerol 3-phosphate dehydrogenase (mGPDH) is a major pathway for transfer of cytosolic reducing…”
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Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury by Brand, Martin D., Goncalves, Renata L.S., Orr, Adam L., Vargas, Leonardo, Gerencser, Akos A., Borch Jensen, Martin, Wang, Yves T., Melov, Simon, Turk, Carolina N., Matzen, Jason T., Dardov, Victoria J., Petrassi, H. Michael, Meeusen, Shelly L., Perevoshchikova, Irina V., Jasper, Heinrich, Brookes, Paul S., Ainscow, Edward K.

“…Using high-throughput screening we identified small molecules that suppress superoxide and/or H2O2 production during reverse electron transport through…”
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Sites of reactive oxygen species generation by mitochondria oxidizing different substrates by Quinlan, Casey L, Perevoshchikova, Irina V, Hey-Mogensen, Martin, Orr, Adam L, Brand, Martin D

“…Mitochondrial radical production is important in redox signaling, aging and disease, but the relative contributions of different production sites are poorly…”
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Native rates of superoxide production from multiple sites in isolated mitochondria measured using endogenous reporters by Quinlan, Casey L., Treberg, Jason R., Perevoshchikova, Irina V., Orr, Adam L., Brand, Martin D.

“…Individual sites of superoxide production in the mitochondrial respiratory chain have previously been defined and partially characterized using specific…”
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Derivatives of Rhodamine 19 as Mild Mitochondria-targeted Cationic Uncouplers by Antonenko, Yuri N., Avetisyan, Armine V., Cherepanov, Dmitry A., Knorre, Dmitry A., Korshunova, Galina A., Markova, Olga V., Ojovan, Silvia M., Perevoshchikova, Irina V., Pustovidko, Antonina V., Rokitskaya, Tatyana I., Severina, Inna I., Simonyan, Ruben A., Smirnova, Ekaterina A., Sobko, Alexander A., Sumbatyan, Natalia V., Severin, Fedor F., Skulachev, Vladimir P.

“…A limited decrease in mitochondrial membrane potential can be beneficial for cells, especially under some pathological conditions, suggesting that mild…”
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Suppressors of superoxide production from mitochondrial complex III by Orr, Adam L, Vargas, Leonardo, Turk, Carolina N, Baaten, Janine E, Matzen, Jason T, Dardov, Victoria J, Attle, Stephen J, Li, Jing, Quackenbush, Douglas C, Goncalves, Renata L S, Perevoshchikova, Irina V, Petrassi, H Michael, Meeusen, Shelly L, Ainscow, Edward K, Brand, Martin D

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Suppressors of Superoxide-H 2 O 2 Production at Site I Q of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury by Brand, Martin D, Goncalves, Renata L S, Orr, Adam L, Vargas, Leonardo, Gerencser, Akos A, Borch Jensen, Martin, Wang, Yves T, Melov, Simon, Turk, Carolina N, Matzen, Jason T, Dardov, Victoria J, Petrassi, H Michael, Meeusen, Shelly L, Perevoshchikova, Irina V, Jasper, Heinrich, Brookes, Paul S, Ainscow, Edward K

“…Using high-throughput screening we identified small molecules that suppress superoxide and/or H O production during reverse electron transport through…”
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Suppressors of superoxide production from mitochondrial complex III by Orr, Adam L, Vargas, Leonardo, Turk, Carolina N, Baaten, Janine E, Matzen, Jason T, Dardov, Victoria J, Attle, Stephen J, Li, Jing, Quackenbush, Douglas C, Goncalves, Renata L S, Perevoshchikova, Irina V, Petrassi, H Michael, Meeusen, Shelly L, Ainscow, Edward K, Brand, Martin D

“…High-throughput chemical screening identified several groups of compounds that selectively block superoxide production from the outer Q-binding site of…”
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Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria by Perevoshchikova, Irina V., Quinlan, Casey L., Orr, Adam L., Gerencser, Akos A., Brand, Martin D.

“…H2O2 production by skeletal muscle mitochondria oxidizing palmitoylcarnitine was examined under two conditions: the absence of respiratory chain inhibitors and…”
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Hexokinase inhibits flux of fluorescently labeled ATP through mitochondrial outer membrane porin by Perevoshchikova, Irina V., Zorov, Savva D., Kotova, Elena A., Zorov, Dmitry B., Antonenko, Yuri N.

“…Mitochondrial function requires maintaining metabolite fluxes across the mitochondrial outer membrane, which is mediated primarily by the voltage dependent…”
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Effect of liposomes on energy-dependent uptake of the antioxidant SkQR1 by isolated mitochondria by Antonenko, Yuri N., Perevoshchikova, Irina V., Rokitskaya, Tatyana I., Simonyan, Ruben A., Tashlitsky, Vadim V., Skulachev, Vladimir P.

“…The mitochondria-targeted antioxidant SkQR1 composed of a plastoquinone part covalently bound to a cationic rhodamine 19 moiety via a decane linker was…”
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Interaction of recombinant analogs of spider silk proteins 1F9 and 2E12 with phospholipid membranes by Antonenko, Yuri N., Perevoshchikova, Irina V., Davydova, Lyubov I., Agapov, Igor A., Bogush, Vladimir G.

“…Recombinant analogs of spider dragline silk proteins 1F9 and 2E12 are characterized by numerous repeats consisting of hydrophobic poly-Ala blocks and Gly-rich…”
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Lack of Oxidative Stress in a Mouse Neural Stem Cell Model of Huntington's Disease by Perevoshchikova', Irina V, Gerencser, Akos A, Brand', Martin D

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49 - Lack of Oxidative Stress in a Mouse Neural Stem Cell Model of Huntington's Disease by Perevoshchikova', Irina V, Gerencser, Akos A, Brand', Martin D

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255 - Novel Insights into Mitochondrial Superoxide/H2O2 Production Rates in Vivo by Goncalves, Renata L S, Quinlan, Casey L, Perevoshchikova, Irina V, Hey-Mogensen, Martin, Brand, Martin D

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Novel Insights into Mitochondrial Superoxide/H2O2 Production Rates in Vivo by Goncalves, Renata L S, Quinlan, Casey L, Perevoshchikova, Irina V, Hey-Mogensen, Martin, Brand, Martin D

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Native Rates of Mitochondrial Superoxide Production: A Novel Method Utilizing Endogenous Reporters by Quinlan, Casey L, Perevoshchikova, Irina V, Orr, Adam L, Hey-Morgensen, Martin, Brand, Martin D

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Characterization and suppression of mitochondrial production of superoxide and hydrogen peroxide under near-physiological conditions by Brand, Martin D., Quinlan, Casey L., Goncalves, Renata L.S., Perevoshchikova, Irina V., Treberg, Jason R., Hey-Mogensen, Martin, Gerencser, Akos A., Orr, Adam L.

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