Search Results - "Peremans, Kathelijne"
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Pharmacokinetics, absolute bioavailability and tolerability of ketamine after intranasal administration to dexmedetomidine sedated dogs
Published in PloS one (01-01-2020)“…Intranasal ketamine has recently gained interest in human medicine, not only for its sedative, anaesthetic or analgesic properties, but also in the management…”
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2
Generation of functional thyroid from embryonic stem cells
Published in Nature (London) (01-11-2012)“…The primary function of the thyroid gland is to metabolize iodide by synthesizing thyroid hormones, which are critical regulators of growth, development and…”
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3
Effect of recombinant human thyroid stimulating hormone on radioactive iodine uptake by thyroid carcinoma in dogs
Published in Journal of veterinary internal medicine (01-07-2024)“…Background The high doses of radioiodine‐131 (131I) and, subsequently, the high radioactive burden for dog and environment warrants optimization of 131I…”
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4
Network analysis reveals abnormal functional brain circuitry in anxious dogs
Published in PloS one (15-03-2023)“…Anxiety is a common disease within human psychiatric disorders and has also been described as a frequently neuropsychiatric problem in dogs. Human neuroimaging…”
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The quorum sensing peptides PhrG, CSP and EDF promote angiogenesis and invasion of breast cancer cells in vitro
Published in PloS one (17-03-2015)“…The role of the human microbiome on cancer progression remains unclear. Therefore, in this study, we investigated the influence of some quorum sensing…”
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Hostility in medication-resistant major depression and comorbid generalized anxiety disorder is related to increased hippocampal–amygdala 5-HT2A receptor density
Published in European archives of psychiatry and clinical neuroscience (01-10-2021)“…Major depressive disorder (MDD) and generalized anxiety disorder (GAD) are severe and difficult-to-treat psychiatric illnesses with high rates of comorbidity…”
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Structural connectome alterations in anxious dogs: a DTI-based study
Published in Scientific reports (19-06-2023)“…Anxiety and fear are dysfunctional behaviors commonly observed in domesticated dogs. Although dogs and humans share psychopathological similarities, little is…”
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Quorum Sensing Peptides Selectively Penetrate the Blood-Brain Barrier
Published in PloS one (04-11-2015)“…Bacteria communicate with each other by the use of signaling molecules, a process called 'quorum sensing'. One group of quorum sensing molecules includes the…”
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9
Low-dose xenogeneic mesenchymal stem cells target canine osteoarthritis through systemic immunomodulation and homing
Published in Arthritis research & therapy (03-10-2023)“…Abstract Background As current therapies for canine osteoarthritis (OA) provide mainly symptomatic improvement and fail to address the complex pathology of the…”
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10
Cell-Penetrating Peptides Selectively Cross the Blood-Brain Barrier In Vivo
Published in PloS one (14-10-2015)“…Cell-penetrating peptides (CPPs) are a group of peptides, which have the ability to cross cell membrane bilayers. CPPs themselves can exert biological activity…”
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11
Behavior in dogs with spontaneous hypothyroidism during treatment with levothyroxine
Published in Journal of veterinary internal medicine (01-01-2019)“…Background Thyroid hormone supplementation anecdotally has been described as a valid treatment option for dogs with aggression‐related problems. However,…”
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12
Chemical-functional diversity in cell-penetrating peptides
Published in PloS one (09-08-2013)“…Cell-penetrating peptides (CPPs) are a promising tool to overcome cell membrane barriers. They have already been successfully applied as carriers for several…”
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13
Human skin permeation of emerging mycotoxins (beauvericin and enniatins)
Published in Journal of exposure science & environmental epidemiology (01-05-2016)“…Currently, dermal exposure data of cyclic depsipeptide mycotoxins are completely absent. There is a lack of understanding about the local skin and systemic…”
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14
PET quantification of [18F]MPPF in the canine brain using blood input and reference tissue modelling
Published in PloS one (11-06-2019)“…Numerous studies have shown that the serotonin1A (5-HT1A) receptor is implicated in the pathophysiology and treatment of several psychiatric and neurological…”
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15
Regional alterations of cerebral [18F]FDG metabolism in the chronic unpredictable mild stress- and the repeated corticosterone depression model in rats
Published in Journal of Neural Transmission (01-09-2018)“…Preclinical research has been indispensable in the exploration of the neurological basis of major depressive disorder (MDD). The present study aimed to examine…”
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The influence of subanaesthetic ketamine on regional cerebral blood flow in healthy dogs measured with 99mTc-HMPAO SPECT
Published in PloS one (2018)“…Subanaesthetic ketamine has recently been proven to be a highly effective and fast acting alternative treatment for several psychiatric disorders. The…”
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17
Anaesthesia, not number of sessions, influences the magnitude and duration of an aHF-rTMS in dogs
Published in PloS one (22-09-2017)“…Currently, the rat has been a useful animal model in brain stimulation research. Nevertheless, extrapolating results from rodent repetitive Transcranial…”
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18
Evaluation of Feline Renal Perfusion with Contrast-Enhanced Ultrasonography and Scintigraphy
Published in PloS one (13-10-2016)“…Contrast-enhanced ultrasound (CEUS) is an emerging technique to evaluate tissue perfusion. Promising results have been obtained in the evaluation of renal…”
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19
Estimation of the optimal dosing regimen of escitalopram in dogs: A dose occupancy study with [11C]DASB
Published in PloS one (23-06-2017)“…Although the favourable characteristics of escitalopram as being the most selective serotonin reuptake inhibitor and having an increased therapeutic efficacy…”
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Scintigraphic tracking of 99mTechnetium-labelled equine peripheral blood-derived mesenchymal stem cells after intravenous, intramuscular, and subcutaneous injection in healthy dogs
Published in Stem cell research & therapy (13-07-2021)“…Abstract Background Mesenchymal stem cell treatments in dogs have been investigated as a potential innovative alternative to current conventional therapies for…”
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