Search Results - "Perelman, Grigory"
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Additive effect of frequent polymorphism and rare synonymous variant alters splicing in twin patients with Niemann-Pick disease type C
Published in European journal of human genetics : EJHG (01-01-2022)“…Niemann-Pick disease type C (NP-C) (OMIM#257220) is a rare lysosomal storage disorder caused by pathogenic variants in either the NPC1 or NPC2 genes. It…”
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A clinical AI-driven multiplex immunofluorescence imaging pipeline to characterize tumor microenvironment heterogeneity
Published in Journal of clinical oncology (01-06-2022)“…3020 Background: Understanding the underlying heterogeneity of the tumor microenvironment (TME) on a single-cell level is becoming increasingly important to…”
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Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patients
Published in Cancer cell (11-03-2024)“…Follicular lymphoma (FL) is a generally incurable malignancy that evolves from developmentally blocked germinal center (GC) B cells. To promote survival and…”
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Abstract 6151: Tumor microenvironment heterogeneity identifies potential biomarkers of response in ER-positive breast cancers treated with palbociclib
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Despite the breast cancer microenvironment being recognized as a critical participant in tumor progression and therapeutic response, current…”
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