Search Results - "Pereira, Petronila Rocha"
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Erythrocyte membrane protein destabilization versus clinical outcome in 160 Portuguese Hereditary Spherocytosis patients
Published in British journal of haematology (01-06-2010)“…Summary Hereditary Spherocytosis (HS) is a haemolytic anaemia caused by erythrocyte protein membrane defects – spectrin, ankyrin, band 3 or protein 4·2 – that…”
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The roles of cells and cytokines in the pathogenesis of psoriasis
Published in International journal of dermatology (01-04-2012)“…Psoriasis is considered an immune chronic disease in which T cells are accepted as important. Nowadays, it is believed that psoriasis is most likely a T helper…”
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Linkage of typically cytosolic peroxidases to erythrocyte membrane – A possible mechanism of protection in Hereditary Spherocytosis
Published in Biochimica et biophysica acta. Biomembranes (01-03-2020)“…Hereditary Spherocytosis (HS) is a non-immune hemolytic anemia associated to oxidative stress (OS), namely to the linkage of cytosolic antioxidant enzymes to…”
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Interleukin 6 (rs1800795) and pentraxin 3 (rs2305619) polymorphisms-association with inflammation and all-cause mortality in end-stage-renal disease patients on dialysis
Published in Scientific reports (20-07-2021)“…Chronic inflammation plays an important role in the progression and outcome of chronic kidney disease (CKD). The circulating levels of the inflammatory…”
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Age-Related Changes in Clinical and Analytical Variables in Chronic Hemodialyzed Patients
Published in International journal of molecular sciences (15-03-2024)“…Worldwide, the number of elderly individuals receiving chronic hemodialysis is rising. The aim of our study was to evaluate several clinical and analytical…”
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Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model
Published in PloS one (13-04-2015)“…Anemia is a common complication of chronic kidney disease (CKD) that develops early and its severity increases as renal function declines. It is mainly due to…”
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Long Pentraxin 3 as a Broader Biomarker for Multiple Risk Factors in End-Stage Renal Disease: Association with All-Cause Mortality
Published in Mediators of inflammation (01-01-2019)“…Persistent inflammation in end-stage renal disease (ESRD) patients is known to underlie the progression of chronic kidney disease and to be associated with…”
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Impact of TNFRSF1B (rs3397, rs1061624 and rs1061622) and IL6 (rs1800796, rs1800797 and rs1554606) Gene Polymorphisms on Inflammatory Response in Patients with End-Stage Kidney Disease Undergoing Dialysis
Published in Biomedicines (31-05-2024)“…We aimed to study the impact of polymorphisms in the genes encoding interleukin-6 (IL6) and tumor necrosis factor receptor-2 (TNFR2), reported to be mortality…”
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Cell-free DNA as a marker for the outcome of end-stage renal disease patients on haemodialysis
Published in Clinical kidney journal (01-05-2021)“…DNA damage and inflammation are common in end-stage renal disease (ESRD). Our aim was to evaluate the levels of circulating cell-free DNA (cfDNA) and the…”
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The effect of green tea in oxidative stress
Published in Clinical nutrition (Edinburgh, Scotland) (01-10-2006)“…Green tea, an infusion prepared with the leaves of Camellia sinensis is particularly rich in flavonoids, which are strong antioxidants. Tea drinking, by…”
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Liver iron is a major regulator of hepcidin gene expression via BMP/SMAD pathway in a rat model of chronic renal failure under treatment with high rHuEPO doses
Published in BioFactors (Oxford) (01-05-2016)“…Hepcidin is the major central regulator of iron metabolism, controlling iron absorption and mobilization. Considering its interaction with several factors that…”
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Body fat percentage is a major determinant of total bilirubin independently of UGT1A128 polymorphism in young obese
Published in PloS one (05-06-2014)“…Bilirubin has potential antioxidant and anti-inflammatory properties. The UGT1A1*28 polymorphism (TA repeats in the promoter region) is a major determinant of…”
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Renal risk-benefit determinants of recombinant human erythropoietin therapy in the remnant kidney rat model - hypertension, anaemia, inflammation and drug dose
Published in Clinical and experimental pharmacology & physiology (01-03-2016)“…Summary Clinical studies showed that high doses of recombinant human erythropoietin (rHuEPO) used to correct anaemia in chronic kidney disease (CKD)…”
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Inflammatory Disturbances in Preeclampsia: Relationship between Maternal and Umbilical Cord Blood
Published in Journal of Pregnancy (01-01-2012)“…Preeclampsia (PE) is one of the main causes of maternal and fetal mortality and morbidity. PE is associated with an inflammatory state and with oxidative…”
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Transition from cyclosporine-induced renal dysfunction to nephrotoxicity in an in vivo rat model
Published in International Journal of Molecular Sciences (20-05-2014)“…Cyclosporin A (CsA), a calcineurin inhibitor, remain the cornerstone of immunosuppressive regimens, regardless of nephrotoxicity, which depends on the duration…”
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Hepcidin and diabetes are independently related with soluble transferrin receptor levels in chronic dialysis patients
Published in Renal failure (01-01-2019)“…Background: Soluble transferrin receptor (sTfR) is a biomarker of erythropoiesis, which is often impaired in dialysis patients. The aim of our study was to…”
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Resistance to Recombinant Human Erythropoietin Therapy in a Rat Model of Chronic Kidney Disease Associated Anemia
Published in International journal of molecular sciences (01-01-2016)“…This study aimed to elucidate the mechanisms explaining the persistence of anemia and resistance to recombinant human erythropoietin (rHuEPO) therapy in a rat…”
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The Association of Leptin with Left Ventricular Hypertrophy in End-Stage Kidney Disease Patients on Dialysis
Published in Biomedicines (27-03-2023)“…Left ventricular hypertrophy (LVH) is a common cardiovascular complication in end-stage kidney disease (ESKD) patients. We aimed at studying the association of…”
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