Search Results - "Pereira, Mirian Cláudia De Souza"

Impact of collaborative actions of Leishmania (Viannia) braziliensis subpopulations on the infection profile by de Albuquerque-Melo, Barbara Cristina, Cysne-Finkelstein, Léa, Gonçalves-Oliveira, Luiz Filipe, Cascabulho, Cynthia Machado, Henriques-Pons, Andrea, Pereira, Mirian Cláudia de Souza, Alves, Carlos Roberto, Dias-Lopes, Geovane

“…This study focuses on the role of the population structure of Leishmania spp. on the adaptive capacity of the parasite. Herein, we investigate the contribution…”
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Trypanosoma janseni n. sp. (Trypanosomatida: Trypanosomatidae) isolated from Didelphis aurita (Mammalia: Didelphidae) in the Atlantic Rainforest of Rio de Janeiro, Brazil: integrative taxonomy and phylogeography within the Trypanosoma cruzi clade by Lopes, Camila Madeira Tavares, Menna-Barreto, Rubem Figueiredo Sadok, Pavan, Márcio Galvão, Pereira, Mirian Cláudia De Souza, Roque, André Luiz R

“…Didelphis spp. are a South American marsupial species that are among the most ancient hosts for the Trypanosoma spp. We characterise a new species (Trypanosoma…”
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Antileishmanial Activity of 2-Methoxy-4H-spiro-[naphthalene-1,2'-oxiran]-4-one (Epoxymethoxy-lawsone): A Promising New Drug Candidate for Leishmaniasis Treatment by Oliveira, Luiz Filipe Gonçalves, Souza-Silva, Franklin, de Castro Côrtes, Luzia Monteiro, Cysne-Finkelstein, Lea, de Souza Pereira, Mirian Cláudia, de Oliveira Junior, Francisco Odêncio, Pinho, Rosa Teixeira, Corte Real, Suzana, Bourguignon, Saulo Cabral, Ferreira, Vitor Francisco, Alves, Carlos Roberto

“…Epoxymethoxylawsone is a naphthoquinone derivative promising as drug candidate for the treatment of leishmaniases. In the present work the effectiveness of…”
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Acute Chagas disease induces cerebral microvasculopathy in mice by Nisimura, Lindice Mitie, Estato, Vanessa, de Souza, Elen Mello, Reis, Patricia A, Lessa, Marcos Adriano, Castro-Faria-Neto, Hugo Caire, Pereira, Mirian Claudia de Souza, Tibiriçá, Eduardo, Garzoni, Luciana Ribeiro

“…Cardiomyopathy is the main clinical form of Chagas disease (CD); however, cerebral manifestations, such as meningoencephalitis, ischemic stroke and cognitive…”
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Differential Role of TGF-β in Extracellular Matrix Regulation During Trypanosoma cruzi -Host Cell Interaction by Silva, Tatiana Araújo, Ferreira, Luis Felipe de Carvalho, Pereira, Mirian Claudia de Souza, Calvet, Claudia Magalhães

“…Transforming growth factor beta (TGF-β) is a determinant for inflammation and fibrosis in cardiac and skeletal muscle in Chagas disease. To determine its…”
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Synthesis by Microwave Irradiation, Molecular Structural Analysis and Trypanocidal Activity of Novel Pyrazole-tetrahydropyrimidine Derivatives by Pereira, Cynthia Nathalia, de Oliveira, Júlia Akihoshi, da Silva Lara, Leonardo, Rocha Orlando, Lorraine Martins, de Souza Pereira, Mirian Claudia, Dos Santos, Maurício Silva

“…A series of new eight 2-(1-aryl-3-methyl-1H-pyrazol-4-yl)-1,4,5,6-tetrahydropyrimidines 1(a-h) were synthesized by microwave irradiation technique. In vitro…”
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Trypanosoma cruzi activates mouse cardiac fibroblasts in vitro leading to fibroblast-myofibroblast transition and increase in expression of extracellular matrix proteins by Coelho, Laura Lacerda, Pereira, Isabela Resende, Pereira, Mirian Claudia de Souza, Mesquita, Liliane, Lannes-Vieira, Joseli, Adesse, Daniel, Garzoni, Luciana Ribeiro

“…Cardiac fibrosis is a consequence of chronic chagasic cardiomyopathy (CCC). In other cardiovascular diseases, the protagonist role of fibroblasts in cardiac…”
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Insights into the tracking of the cysteine proteinase B COOH-terminal polypeptide of Leishmania (Leishmania) amazonensis by surface plasmon resonance by Santos-de-Souza, Raquel, Souza-Silva, Franklin, de Albuquerque-Melo, Barbara Cristina, Ribeiro-Guimarães, Michelle Lopes, de Castro Côrtes, Luzia Monteiro, Pereira, Bernardo Acácio Santini, Silva-Almeida, Mariana, Cysne-Finkelstein, Léa, de Oliveira Junior, Francisco Odencio Rodrigues, Pereira, Mirian Claudia de Souza, Alves, Carlos Roberto

“…Leishmania ( Leishmania ) amazonensis has adaptive mechanisms to the host environment that are guided by its proteinases, including cysteine proteinase B…”
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Interactions between 4-aminoquinoline and heme: Promising mechanism against Trypanosoma cruzi by Lechuga, Guilherme Curty, Borges, Júlio Cesar, Calvet, Claudia Magalhães, de Araújo, Humberto Pinheiro, Zuma, Aline Araujo, do Nascimento, Samara Braga, Motta, Maria Cristina Machado, Bernardino, Alice Maria Rolim, Pereira, Mirian Claudia de Souza, Bourguignon, Saulo Cabral

“…Chagas disease is a neglected tropical disease caused by the flagellated protozoan Trypanosoma cruzi. The current drugs used to treat this disease have limited…”
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Synthesis and Anti- Trypanosoma cruzi Activity of New Pyrazole-Thiadiazole Scaffolds by Souza, Thamyris Perez de, Orlando, Lorraine Martins Rocha, Lara, Leonardo da Silva, Paes, Vitoria Barbosa, Dutra, Lucas Penha, Dos Santos, Mauricio Silva, Pereira, Mirian Claudia de Souza

“…Chagas disease, a silent but widespread disease that mainly affects a socioeconomically vulnerable population, lacks innovative safe drug therapy. The…”
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Increased angiogenesis parallels cardiac tissue remodelling in experimental acute Trypanosoma cruzi infection by Nisimura, Lindice Mitie, Ferreira, Roberto Rodrigues, Coelho, Laura Lacerda, Souza, Elen Mello de, Gonzaga, Beatriz Matheus, Ferrão, Patrícia Mello, Waghabi, Mariana Caldas, Mesquita, Liliane Batista de, Pereira, Mirian Claudia de Souza, Moreira, Otacilio da Cruz, Lannes-Vieira, Joseli, Garzoni, Luciana Ribeiro

“…Angiogenesis has been implicated in tissue injury in several noninfectious diseases, but its role in Chagas disease (CD) physiopathology is unclear. The…”
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In the Acute Phase of Trypanosoma cruzi Infection, Liver Lymphoid and Myeloid Cells Display an Ambiguous Phenotype Combining Pro- and Anti-Inflammatory Markers by de Lima Pereira dos Santos, Carina, Vacani-Martins, Natalia, Cascabulho, Cynthia Machado, Pereira, Mirian Claudia de Souza, Crispe, Ian Nicholas, Henriques-Pons, Andrea

“…Multiple cell populations, cellular biochemical pathways, and the autonomic nervous system contribute to maintaining the immunological tolerance in the liver…”
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Antitrypanosomal Activity of 1,2,3-Triazole-Based Hybrids Evaluated Using In Vitro Preclinical Translational Models by Orlando, Lorraine Martins Rocha, Lara, Leonardo da Silva, Lechuga, Guilherme Curty, Rodrigues, Giseli Capaci, Pandoli, Omar Ginoble, de Sá, Druval Santos, Pereira, Mirian Claudia de Souza

“…Chagas disease therapy still relies on two nitroderivatives, nifurtimox and benznidazole (Bz), which have important limitations and serious adverse effects…”
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Detection of matrix metallopeptidase-9-like proteins in Trypanosoma cruzi by Nogueira de Melo, Ana Cristina, de Souza, Edilma Paraguai, Elias, Camila Guarany Ramalho, dos Santos, André Luis Souza, Branquinha, Marta Helena, d’Ávila-Levy, Cláudia Masini, dos Reis, Flávia Coelho Garcia, Costa, Tatiana Ferreira Rocha, de Araujo Lima, Ana Paula Cabral, de Souza Pereira, Mirian Cláudia, Meirelles, Maria Nazareth Leal, Vermelho, Alane Beatriz

“…In this study, the cell-associated and extracellular peptidases of Trypanosoma cruzi grown in modified Roitman’s complex (MRC) medium were analyzed by…”
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4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection by Calvet, Claudia Magalhaes, Choi, Jun Yong, Thomas, Diane, Suzuki, Brian, Hirata, Ken, Lostracco-Johnson, Sharon, de Mesquita, Liliane Batista, Nogueira, Alanderson, Meuser-Batista, Marcelo, Silva, Tatiana Araujo, Siqueira-Neto, Jair Lage, Roush, William R, de Souza Pereira, Mirian Claudia, McKerrow, James H, Podust, Larissa M

“…Chagas disease, caused by the protozoan Trypanosoma cruzi, is the leading cause of heart failure in Latin America. The clinical treatment of Chagas disease is…”
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Bioactivity of Novel Pyrazole-Thiazolines Scaffolds against Trypanosoma cruzi : Computational Approaches and 3D Spheroid Model on Drug Discovery for Chagas Disease by Lara, Leonardo da Silva, Lechuga, Guilherme Curty, Orlando, Lorraine Martins Rocha, Ferreira, Byanca Silva, Souto, Bernardo Araújo, Dos Santos, Maurício Silva, Pereira, Mirian Claudia de Souza

“…Chagas disease, a century-old disease that mainly affects the impoverished population in Latin America, causes high morbidity and mortality in endemic…”
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Natural products from marine red and brown algae against Trypanosoma cruzi by Teixeira, Valéria Laneuville, Lima, Juliana Coelho Rodrigues, Lechuga, Guilherme Curty, Ramos, Carlos José Brito, Pereira, Mirian Claudia de Souza, Calvet, Claudia Magalhães, Bourguignon, Saulo Cabral

“…[Display omitted] Various extracts obtained from the red alga Plocamium brasiliense (Greville Howe & Taylor), including a fraction containing crude…”
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Leishmania major: Parasite interactions suggesting sexuality by Maria Auxiliadora de Sousa, Mirian Claudia de Souza Pereira, Suzana Corte-Real

“…In five experiments, Leishmania (Leishmania) major (MRHO/SU/59/P-strain) grew poorly when seeded in FYTS medium supplemented with 15% fetal calf serum, but…”
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Trypanosoma janseni n. sp. (Trypanosomatida: Trypanosomatidae) isolated from Didelphis aurita (Mammalia: Didelphidae) in the Atlantic Rainforest of Rio de Janeiro, Brazil: integrative taxonomy and phylogeography within the Trypanosoma cruzi clade by Lopes, Camila Madeira Tavares, Menna-Barreto, Rubem Figueiredo Sadok, Pavan, Márcio Galvão, Pereira, Mirian Cláudia de Souza, Roque, André Luiz R

“…BACKGROUND Didelphis spp. are a South American marsupial species that are among the most ancient hosts for the Trypanosoma spp. OBJECTIVES We characterise a…”
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TGF-β receptor type II costameric localization in cardiomyocytes and host cell TGF-β response is disrupted by Trypanosoma cruzi infection by Calvet, Claudia Magalhães, Silva, Tatiana Araújo, DE Melo, Tatiana Galvão, DE Araújo-Jorge, Tânia Cremonini, Pereira, Mirian Claudia DE Souza

“…Transforming growth factor beta (TGF-β) cytokine is involved in Chagas disease establishment and progression. Since Trypanosoma cruzi can modulate host cell…”
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