Search Results - "Pereira, Michelle R"

Correlation between circulating tumour DNA and metabolic tumour burden in metastatic melanoma patients by McEvoy, Ashleigh C, Warburton, Lydia, Al-Ogaili, Zeyad, Celliers, Liesl, Calapre, Leslie, Pereira, Michelle R, Khattak, Muhammad A, Meniawy, Tarek M, Millward, Michael, Ziman, Melanie, Gray, Elin S

“…Circulating tumour DNA (ctDNA) may serve as a measure of tumour burden and a useful tool for non-invasive monitoring of cancer. However, ctDNA is not always…”
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Locus‐specific concordance of genomic alterations between tissue and plasma circulating tumor DNA in metastatic melanoma by Calapre, Leslie, Giardina, Tindaro, Robinson, Cleo, Reid, Anna L., Al‐Ogaili, Zeyad, Pereira, Michelle R., McEvoy, Ashleigh C., Warburton, Lydia, Hayward, Nicholas K., Khattak, Muhammad A., Meniawy, Tarek M., Millward, Michael, Amanuel, Benhur, Ziman, Melanie, Gray, Elin S.

“…Circulating tumor DNA (ctDNA) may serve as a surrogate to tissue biopsy for noninvasive identification of mutations across multiple genetic loci and for…”
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Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma by Gray, Elin S, Rizos, Helen, Reid, Anna L, Boyd, Suzanah C, Pereira, Michelle R, Lo, Johnny, Tembe, Varsha, Freeman, James, Lee, Jenny H J, Scolyer, Richard A, Siew, Kelvin, Lomma, Chris, Cooper, Adam, Khattak, Muhammad A, Meniawy, Tarek M, Long, Georgina V, Carlino, Matteo S, Millward, Michael, Ziman, Melanie

“…Repeat tumor biopsies to study genomic changes during therapy are difficult, invasive and data are confounded by tumoral heterogeneity. The analysis of…”
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Detection of clinical progression through plasma ctDNA in metastatic melanoma patients: a comparison to radiological progression by Marsavela, Gabriela, McEvoy, Ashleigh C., Pereira, Michelle R., Reid, Anna L., Al-Ogaili, Zeyad, Warburton, Lydia, Khattak, Muhammad A., Abed, Afaf, Meniawy, Tarek M., Millward, Michael, Ziman, Melanie R., Calapre, Leslie, Gray, Elin S.

“…Background The validity of circulating tumour DNA (ctDNA) as an indicator of disease progression compared to medical imaging in patients with metastatic…”
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Circulating Tumor DNA Predicts Outcome from First-, but not Second-line Treatment and Identifies Melanoma Patients Who May Benefit from Combination Immunotherapy by Marsavela, Gabriela, Lee, Jenny, Calapre, Leslie, Wong, Stephen Q, Pereira, Michelle R, McEvoy, Ashleigh C, Reid, Anna L, Robinson, Cleo, Warburton, Lydia, Abed, Afaf, Khattak, Muhammad A, Meniawy, Tarek M, Dawson, Sarah-Jane, Sandhu, Shahneen, Carlino, Matteo S, Menzies, Alexander M, Scolyer, Richard A, Long, Georgina V, Amanuel, Benhur, Millward, Michael, Ziman, Melanie R, Rizos, Helen, Gray, Elin S

“…We evaluated the predictive value of pretreatment ctDNA to inform therapeutic outcomes in patients with metastatic melanoma relative to type and line of…”
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A comparative study of extracellular vesicle-associated and cell-free DNA and RNA for HPV detection in oropharyngeal squamous cell carcinoma by Nguyen, Bella, Meehan, Katie, Pereira, Michelle R., Mirzai, Bob, Lim, Si Hong, Leslie, Connull, Clark, Michael, Sader, Chady, Friedland, Peter, Lindsay, Andrew, Tang, Colin, Millward, Michael, Gray, Elin S., Lim, Annette M.

“…Purpose: This study compares the detection sensitivity of two separate liquid biopsy sources, cell-free (cf) DNA/RNA and extracellular vesicle (EV)-associated…”
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Circulating Tumour DNA in Advanced Melanoma Patients Ceasing PD1 Inhibition in the Absence of Disease Progression by Warburton, Lydia, Calapre, Leslie, Pereira, Michelle R., Reid, Anna, Robinson, Cleo, Amanuel, Benhur, Ziman, Mel, Millward, Michael, Gray, Elin

“…Immunotherapy is an important and established treatment option for patients with advanced melanoma. Initial anti-PD1 trials arbitrarily defined a two-year…”
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Droplet Digital PCR for Mutation Detection in Formalin-Fixed, Paraffin-Embedded Melanoma Tissues: A Comparison with Sanger Sequencing and Pyrosequencing by McEvoy, Ashleigh C, Wood, Benjamin A, Ardakani, Nima M, Pereira, Michelle R, Pearce, Robert, Cowell, Lester, Robinson, Cleo, Grieu-Iacopetta, Fabienne, Spicer, Alexander J, Amanuel, Benhur, Ziman, Melanie, Gray, Elin S

“…The identification of somatic mutations is crucial for guiding therapeutic decisions about personalized melanoma treatment. However, genetic analysis of tumors…”
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Sensitive droplet digital PCR method for detection of TERT promoter mutations in cell free DNA from patients with metastatic melanoma by McEvoy, Ashleigh C, Calapre, Leslie, Pereira, Michelle R, Giardina, Tindaro, Robinson, Cleo, Khattak, Muhammad A, Meniawy, Tarek M, Pritchard, Antonia L, Hayward, Nicholas K, Amanuel, Benhur, Millward, Michael, Ziman, Melanie, Gray, Elin S

“…Currently mainly mutant circulating tumor DNA (ctDNA) is utilized to monitor patients with melanoma. promoter mutations are common in various cancers and found…”
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Detection of metastases using circulating tumour DNA in uveal melanoma by Beasley, Aaron B., de Bruyn, Daniël P., Calapre, Leslie, Al-Ogaili, Zeyad, Isaacs, Timothy W., Bentel, Jacqueline, Reid, Anna L., Dwarkasing, Roy S., Pereira, Michelle R., Khattak, Muhammad A., Meniawy, Tarek M., Millward, Michael, Brosens, Erwin, de Klein, Annelies, Chen, Fred K., Kiliҫ, Emine, Gray, Elin S.

“…Background Approximately 50% of uveal melanoma (UM) patients will develop metastatic disease depending on the genetic features of the primary tumour. Patients…”
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Monitoring melanoma recurrence with circulating tumor DNA: a proof of concept from three case studies by McEvoy, Ashleigh C, Pereira, Michelle R, Reid, Anna, Pearce, Robert, Cowell, Lester, Al-Ogaili, Zeyad, Khattak, Muhammad A, Millward, Michael, Meniawy, Tarek M, Gray, Elin S, Ziman, Melanie

“…A significant number of melanoma patients experience recurrence to distant sites, despite having had surgical treatment of the primary lesion, with curative…”
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The Prognostic Impact of Circulating Tumour DNA in Melanoma Patients Treated with Systemic Therapies-Beyond BRAF Mutant Detection by Marsavela, Gabriela, Johansson, Peter A, Pereira, Michelle R, McEvoy, Ashleigh C, Reid, Anna L, Robinson, Cleo, Warburton, Lydia, Khattak, Muhammad A, Meniawy, Tarek M, Amanuel, Benhur, Millward, Michael, Hayward, Nicholas K, Ziman, Melanie R, Gray, Elin S, Calapre, Leslie

“…In this study, we evaluated the predictive value of circulating tumour DNA (ctDNA) to inform therapeutic outcomes in metastatic melanoma patients receiving…”
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Detection of BRAF splicing variants in plasma-derived cell-free nucleic acids and extracellular vesicles of melanoma patients failing targeted therapy therapies by Clark, Michael E, Rizos, Helen, Pereira, Michelle R, McEvoy, Ashleigh C, Marsavela, Gabriela, Calapre, Leslie, Meehan, Katie, Ruhen, Olivia, Khattak, Muhammad A, Meniawy, Tarek M, Long, Georgina V, Carlino, Matteo S, Menzies, Alexander M, Millward, Michael, Ziman, Melanie, Gray, Elin S

“…The analysis of plasma circulating tumour nucleic acids provides a non-invasive approach to assess disease burden and the genetic evolution of tumours in…”
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Analysis of Circulating Tumour Cells in Early-Stage Uveal Melanoma: Evaluation of Tumour Marker Expression to Increase Capture by Beasley, Aaron B, Isaacs, Timothy W, Vermeulen, Tersia, Freeman, James, DeSousa, Jean-Louis, Bhikoo, Riyaz, Hennessy, Doireann, Reid, Anna, Chen, Fred K, Bentel, Jacqueline, McKay, Daniel, Conway, R Max, Pereira, Michelle R, Mirzai, Bob, Calapre, Leslie, Erber, Wendy N, Ziman, Melanie R, Gray, Elin S

“…(1) Background: The stratification of uveal melanoma (UM) patients into prognostic groups is critical for patient management and for directing patients towards…”
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Droplet Digital PCR for Mutation Detection in Formalin-Fixed, Paraffin-Embedded Melanoma Tissues by McEvoy, Ashleigh C., Wood, Benjamin A., Ardakani, Nima M., Pereira, Michelle R., Pearce, Robert, Cowell, Lester, Robinson, Cleo, Grieu-Iacopetta, Fabienne, Spicer, Alexander J., Amanuel, Benhur, Ziman, Melanie, Gray, Elin S.

“…The identification of somatic mutations is crucial for guiding therapeutic decisions about personalized melanoma treatment. However, genetic analysis of tumors…”
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