Search Results - "Pereira, Marta P."
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Generation of mitochondrial reactive oxygen species is controlled by ATPase inhibitory factor 1 and regulates cognition
Published in PLoS biology (13-05-2021)“…The mitochondrial ATP synthase emerges as key hub of cellular functions controlling the production of ATP, cellular signaling, and fate. It is regulated by the…”
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The therapeutic use of clonal neural stem cells in experimental Parkinson´s disease
Published in Stem cell research & therapy (09-10-2024)“…Parkinson´s disease (PD), the second most common neurodegenerative disease in the world, is characterized by the death or impairment of dopaminergic neurons…”
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Transplanted Stem Cell‐Secreted Vascular Endothelial Growth Factor Effects Poststroke Recovery, Inflammation, and Vascular Repair
Published in Stem cells (Dayton, Ohio) (01-02-2011)“…Cell transplantation offers a novel therapeutic strategy for stroke; however, how transplanted cells function in vivo is poorly understood. We show for the…”
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Genomic Characterization of the Historical Smallpox Vaccine Strain Wyeth Isolated from a 1971 Seed Vial
Published in Viruses (28-12-2022)“…The Wyeth strain of vaccinia virus (VACV) produced by Wyeth Pharmaceuticals was supposedly used to manufacture the old freeze-dried American smallpox vaccine,…”
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Systemic augmentation of αB-crystallin provides therapeutic benefit twelve hours post-stroke onset via immune modulation
Published in Proceedings of the National Academy of Sciences - PNAS (09-08-2011)“…Tissue plasminogen activator is the only treatment option for stroke victims; however, it has to be administered within 4.5 h after symptom onset, making its…”
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R-Ras1 and R-Ras2 Expression in Anatomical Regions and Cell Types of the Central Nervous System
Published in International journal of molecular sciences (17-01-2022)“…Since the optic nerve is one of the most myelinated tracts in the central nervous system (CNS), many myelin diseases affect the visual system. In this sense,…”
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Multifactoriality of Parkinson's Disease as Explored Through Human Neural Stem Cells and Their Transplantation in Middle-Aged Parkinsonian Mice
Published in Frontiers in pharmacology (19-01-2022)“…Parkinson's disease (PD) is an age-associated neurodegenerative disorder for which there is currently no cure. Cell replacement therapy is a potential…”
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Chronic inhibition of the mitochondrial ATP synthase in skeletal muscle triggers sarcoplasmic reticulum distress and tubular aggregates
Published in Cell death & disease (22-06-2022)“…Tubular aggregates (TA) are honeycomb-like arrays of sarcoplasmic-reticulum (SR) tubules affecting aged glycolytic fibers of male individuals and inducing…”
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Analysis of protein glycation using phenylboronate acrylamide gel electrophoresis
Published in Proteomics (Weinheim) (01-01-2010)“…The incorporation of the specialized carbohydrate affinity ligand methacrylamido phenylboronic acid in polyacrylamide gels for SDS-PAGE analysis has been…”
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The Development of Boronic Acids as Sensors and Separation Tools
Published in Chemical record (01-10-2012)“…Synthetic receptors for diols that incorporate boronic acid motifs have been developed as new sensors and separation tools. Utilizing the reversible…”
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Human neural stem cells enhance structural plasticity and axonal transport in the ischaemic brain
Published in Brain (London, England : 1878) (01-06-2011)Get full text
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Analysis of protein glycation using fluorescent phenylboronate gel electrophoresis
Published in Scientific reports (27-03-2013)“…Glycated proteins are important biomarkers for age-related disorders, however their analysis is challenging because of the complexity of the…”
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Short-Term Grafting of Human Neural Stem Cells: Electrophysiological Properties and Motor Behavioral Amelioration in Experimental Parkinsons Disease
Published in Cell transplantation (01-12-2016)“…Cell replacement therapy in Parkinsons disease (PD) still lacks a study addressing the acquisition of electrophysiological properties of human grafted neural…”
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Colonic bacterial translocation as a possible factor in stress-worsening experimental stroke outcome
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-04-2009)“…Stress is known to be one of the risk factors of stroke, but only a few experimental studies have examined the possible mechanisms by which prior stress may…”
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Dye displacement assay for saccharide detection with boronate hydrogels
Published in Chemical communications (Cambridge, England) (01-01-2009)“…Hydrogel spheres, fashioned from an operationally simple mould, that incorporate boronate units were shown to function as saccharide sensors…”
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Human neural stem cells enhance structural plasticity and axonal transport in the ischaemic brain
Published in Brain (London, England : 1878) (01-06-2011)“…Stem cell transplantation promises new hope for the treatment of stroke although significant questions remain about how the grafted cells elicit their effects…”
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Dysfunctional oxidative phosphorylation shunts branched‐chain amino acid catabolism onto lipogenesis in skeletal muscle
Published in The EMBO journal (15-07-2020)“…It is controversial whether mitochondrial dysfunction in skeletal muscle is the cause or consequence of metabolic disorders. Herein, we demonstrate that…”
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R‐Ras1 and R‐Ras2 regulate mature oligodendrocyte subpopulations
Published in Glia (19-11-2024)“…Abstract In the mammalian central nervous system, axonal myelination, executed by mature oligodendrocytes (MOLs), enables rapid neural transmission…”
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