Search Results - "Pereira, Luíza Dantas"
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Extracellular Vesicles: Potential Role in Remote Signaling and Inflammation in Trypanosoma cruzi -Triggered Disease
Published in Frontiers in cell and developmental biology (20-12-2021)“…Extracellular vesicles (EVs) act as cell communicators and immune response modulators and may be employed as disease biomarkers and drug delivery systems. In…”
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Benznidazole and amiodarone combined treatment attenuates cytoskeletal damage in Trypanosoma cruzi-infected cardiac cells
Published in Frontiers in cellular and infection microbiology (25-08-2022)“…Chagas disease (CD), a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi , is an important public health problem mainly in Latin…”
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Antiviral activity of terpenes isolated from marine brown seaweeds against herpes simplex virus type 2
Published in Natural product research (06-12-2023)“…Herpes simplex virus type 2 (HSV-2) is the most common agent of sexually transmitted infections around the world. Currently, no vaccine is available, and…”
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Physical Exercise Promotes a Reduction in Cardiac Fibrosis in the Chronic Indeterminate Form of Experimental Chagas Disease
Published in Frontiers in immunology (04-11-2021)“…Chagas disease (CD), caused by the protozoan , is a neglected tropical disease and a health problem in Latin America. Etiological treatment has limited…”
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Extracellular vesicles from primary human macrophages stimulated with VIP or PACAP mediate anti-SARS-CoV-2 activities in monocytes through NF-κB signaling pathway
Published in Microbes and infection (26-07-2024)“…Infection by SARS-CoV-2 is associated with uncontrolled inflammatory response during COVID-19 severe disease, in which monocytes are one of the main sources of…”
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Ruthenium(II)- and Palladium(II)-catalyzed position-divergent CH oxygenations of arylated quinones: Identification of hydroxylated quinonoid compounds with potent trypanocidal activity
Published in Bioorganic & medicinal chemistry (15-06-2021)“…This article provides a diversity-oriented synthesis of hydroxylated aryl-quinones via CH oxygenation reactions and their evaluation against Trypanosoma cruzi…”
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1-Aryl-1H- and 2-aryl-2H-1,2,3-triazole derivatives blockade P2X7 receptor in vitro and inflammatory response in vivo
Published in European journal of medicinal chemistry (20-10-2017)“…Fifty-one 1,2,3-triazole derivatives were synthesized and evaluated with respect to P2X7 receptor (P2X7R) activity and its associated pore. These triazoles…”
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Strategies towards potent trypanocidal drugs: Application of Rh-catalyzed [2 + 2 + 2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi
Published in Bioorganic & medicinal chemistry (01-08-2020)“…This article provides a comprehensive outline of reactions involving over 120 compounds aimed at the discovery of new quinone-based frameworks with activity…”
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1-Aryl-1 H - and 2-aryl-2 H -1,2,3-triazole derivatives blockade P2X7 receptor in vitro and inflammatory response in vivo
Published in European journal of medicinal chemistry (01-10-2017)Get full text
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