Search Results - "Pereira, Leila Beltrao"
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TNF-α and IL-10 polymorphisms increase the risk to hepatocellular carcinoma in HCV infected individuals
Published in Journal of medical virology (01-09-2016)“…Hepatitis C virus (HCV) is the major cause of hepatocellular carcinoma (HCC). The risk to develop HCC increases with the severity of liver inflammation and…”
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IL‐22 and IL‐22 binding protein (IL‐22BP) regulate fibrosis and cirrhosis in hepatitis C virus and schistosome infections
Published in Hepatology (Baltimore, Md.) (01-04-2015)“…Interleukin (IL)‐22 acts on epithelia, hepatocytes, and pancreatic cells and stimulates innate immunity, tissue protection, and repair. IL‐22 may also cause…”
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Hepatocellular carcinoma recurrence after liver transplantation in a Brazilian multicenter study: clinical profile and prognostic factors of survival
Published in European journal of gastroenterology & hepatology (01-09-2019)“…BACKGROUNDLiver transplantation (LT) is the treatment of choice for patients with unresectable early hepatocellular carcinoma (HCC). Post-LT HCC recurrence…”
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Cost-effectiveness analysis of universal childhood hepatitis A vaccination in Brazil: Regional analyses according to the endemic context
Published in Vaccine (14-12-2012)“…Abstract Objective To conduct a cost-effectiveness analysis of a universal childhood hepatitis A vaccination program in Brazil. Methods An age and…”
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Liver expression of IL-22, IL-22R1 and IL-22BP in patients with chronic hepatitis C with different fibrosis stages
Published in Cytokine (Philadelphia, Pa.) (01-02-2022)“…•Liver biopsies at stage F1 to F3 expressed more IL-22 than F0 or F4.•The number of cells expressing IL-22R1 decreased as fibrosis increased.•There was an…”
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Association of hepatitis C virus infection and liver fibrosis severity with the variants alleles of MBL2 gene in a Brazilian population
Published in Human immunology (01-09-2010)“…Abstract Mannose binding lectin (MBL) is a molecule of the innate immunity, which activates the complement system and modulates inflammation. We investigated…”
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Factors Associated with 30-Day Mortality in Patients after Percutaneous Endoscopic Gastrostomy
Published in Journal of the Society of Laparoendoscopic Surgeons (01-07-2021)“…Percutaneous endoscopic gastrostomy (PEG) is the main accepted method for long-term tube feeding. The aim of this study is to investigate the risk factors…”
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Two sides of a coin: GG genotype of C7 provides protection against fibrosis severity while showing a higher risk for hepatocellular carcinoma in patients with hepatitis C
Published in Human immunology (01-09-2018)“…The complement system (CS) is a key element of immunity against pathogens but also seems to influence other events, such as tumorigenesis and tissue repair…”
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Multilevel analysis of hepatitis A infection in children and adolescents: a household survey in the Northeast and Central-west regions of Brazil
Published in International journal of epidemiology (01-08-2008)“…Background The objectives were to estimate the prevalence of hepatitis A among children and adolescents from the Northeast and Midwest regions and the Federal…”
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Clinical and laboratory parameters associated with li-rads as diagnostic of liver nodule in patients with cirrhosis
Published in Translational gastroenterology and hepatology (01-10-2021)“…Hepatocellular carcinoma (HCC) is the most common primary liver cancer in the world. Clinical and laboratory evaluation of a cirrhotic patient with a liver…”
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Methodology of a nationwide cross-sectional survey of prevalence and epidemiological patterns of hepatitis A, B and C infection in Brazil
Published in Cadernos de saúde pública (01-09-2010)“…A population-based survey to provide information on the prevalence of hepatitis viral infection and the pattern of risk factors was carried out in the urban…”
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Low IL10 serum levels as key factor for predicting the sustained virological response to IFNα/ribavirin in Brazilian patients with HCV carrying IL28B CT/TT genotype
Published in Human immunology (01-08-2014)“…Abstract Propose IL28B polymorphisms rs12979860 CC genotype was associated to protection of HCV infection and sustained virological response (SVR) in HCV…”
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Myeloperoxidase gene polymorphism predicts fibrosis severity in women with hepatitis C
Published in Human immunology (01-08-2014)“…Abstract Oxidative stress plays an important role on liver fibrosis progression in the course of hepatitis C virus (HCV) infection. Myeloperoxidase (MPO) is an…”
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Modelling the force of infection for hepatitis A in an urban population-based survey: a comparison of transmission patterns in Brazilian macro-regions
Published in PloS one (20-05-2014)“…This study aimed to identify the transmission pattern of hepatitis A (HA) infection based on a primary dataset from the Brazilian National Hepatitis Survey in…”
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Plasmatic higher levels of homocysteine in non-alcoholic fatty liver disease (NAFLD)
Published in Nutrition journal (02-04-2013)“…Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease, which includes a spectrum of hepatic pathology such as simple steatosis, steatohepatitis,…”
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Plasma myeloperoxidase levels correlate with hepatocellular carcinoma in chronic hepatitis C
Published in Human immunology (01-11-2012)“…Abstract Myeloperoxidase (MPO) is an enzyme responsible for generating hypochlorous acid and reactive oxidants that may lead to liver injury and cancer in…”
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Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes
Published in International journal of infectious diseases (01-08-2011)“…Summary Background Mannose-binding lectin (MBL) activates the complement system promoting opsonophagocytosis, which could represent an advantage for…”
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Lack of Association of Polymorphisms in IL22 and IL22RA1 Genes with Fibrosis Severity in Patients with Chronic Hepatitis C
Published in Viral immunology (01-09-2022)“…The IL-22 pathway has been shown to play an important role in the pathogenesis of liver fibrosis. However, little is known about the role of single-nucleotide…”
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