Search Results - "Pereira, João D."
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Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex
Published in Proceedings of the National Academy of Sciences - PNAS (07-09-2010)“…Multipotent progenitor cells of the cerebral cortex balance self-renewal and differentiation to produce complex neural lineages in a fixed temporal order in a…”
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Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions
Published in Nature communications (06-08-2021)“…Human induced pluripotent stem cells (iPSC) hold promise for modeling diseases in individual human genetic backgrounds and thus for developing precision…”
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3
The selective cytotoxicity of new triazene compounds to human melanoma cells
Published in Bioorganic & medicinal chemistry (01-08-2017)“…[Display omitted] •Triazene derivatives containing hydroxyphenylalkyl carboxylic acids activated by tyrosinase were reported.•High affinity for tyrosinase was…”
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Synthesis and evaluation of N-acylamino acids derivatives of triazenes. Activation by tyrosinase in human melanoma cell lines
Published in European journal of medicinal chemistry (01-12-2013)“…In this research work we report the synthesis of a new series of triazene prodrugs designed for Melanocyte-Directed Enzyme Prodrug Therapy (MDEPT). These…”
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5
Single-cell analysis of the fate of c-kit-positive bone marrow cells
Published in npj Regenerative medicine (16-10-2017)“…The plasticity of c-kit-positive bone marrow cells (c-kit-BMCs) in tissues different from their organ of origin remains unclear. We tested the hypothesis that…”
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Subcutaneous tissue reaction and cytotoxicity of polyvinylidene fluoride and polyvinylidene fluoride-trifluoroethylene blends associated with natural polymers
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-10-2013)“…Cytotoxicity and subcutaneous tissue reaction of innovative blends composed by polyvinylidene fluoride and polyvinylidene fluoride‐trifluoroethylene associated…”
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Pharmacological Profiling of Purified Human Stem Cell-Derived and Primary Mouse Motor Neurons
Published in Scientific reports (25-07-2019)“…Directed differentiation of human pluripotent stem cells (hPSCs) has enabled the generation of specific neuronal subtypes that approximate the intended primary…”
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Evidence for a retinal progenitor cell in the postnatal and adult mouse
Published in Stem cell research (01-08-2017)“…Progress in cell therapy for retinal disorders has been challenging. Recognized retinal progenitors are a heterogeneous population of cells that lack surface…”
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Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial
Published in JAMA neurology (01-02-2021)“…Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of the motor nervous system. Clinical studies have demonstrated cortical and…”
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Composition of the leaf, flower and fruit volatile oils of Pittosporum tobira (Thunb.) W. T. Aiton grown in three locations in Portugal
Published in Flavour and fragrance journal (01-07-2007)“…The yields of the essential oils isolated from the aerial parts of Pittosporum tobira grown in three different locations in Lisbon, Portugal, were determined…”
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Abstract 14: The Cytoskeletal Architecture of Myocytes Derived from Human Cardiac Progenitor Cells
Published in Circulation research (18-07-2014)“…Abstract only The stem cell antigen c-kit characterizes a heterogeneous pool of human cardiac progenitor cells (hCPCs) that exhibit a remarkable degree of…”
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Abstract 235: Molecular Signature Of Cardiomyogenic c-kit-positive Bone Marrow Cells
Published in Circulation research (18-07-2014)“…Abstract only Conflicting results have been reported concerning the ability of c-kit-positive bone marrow cells (c-kit-BMCs) to transdifferentiate into…”
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Biomaterials from blends of fluoropolymers and corn starch—implant and structural aspects
Published in Materials Science & Engineering C (01-03-2014)“…The development of polymeric blends to be used as matrices for bone regeneration is a hot topic nowadays. In this article we report on the blends composed by…”
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14
Subcutaneous tissue reaction and cytotoxicity of polyvinylidene fluoride and polyvinylidene fluoride-trifluoroethylene blends associated with natural polymers: Tissue Reaction and Cytotoxicity of PVDF and P(VDF-TrFE)
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-10-2013)Get full text
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Experimental leptospirosis in marmoset monkeys (Callithrix jacchus): a new model for studies of severe pulmonary leptospirosis
Published in The American journal of tropical medicine and hygiene (01-01-2005)“…Experimental infection of marmoset monkeys (Callithrix jacchus) with Leptospira interrogans serovar Copenhageni showed microscopic patterns of tissue reactions…”
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A Platform for IEEE 1451 Standard's Education, Development and Validation for Industry 4.0
Published in 2020 IEEE International Instrumentation and Measurement Technology Conference (I2MTC) (01-05-2020)“…The fourth industrial revolution is supported by concepts such as the Internet of Things and Cyber-Physical Systems. Introducing these concepts, a digital…”
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Conference Proceeding -
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Atrial Fibrillation as an Ischemic Stroke Clinical and Economic Burden Modifier: A 15-Year Nationwide Study
Published in Value in health (01-09-2017)“…Abstract Background Atrial fibrillation (AF) is a major risk factor for ischemic stroke (IS). Patients with AF may undergo preventive therapy. Although the AF…”
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Experience on Mechanical Thrombectomy for Acute Stroke Treatment in a Brazilian University Hospital
Published in Journal of stroke and cerebrovascular diseases (01-03-2017)“…Background Brazil is a developing country struggling to reduce its extreme social inequality, which is reflected on shortage of health-care infrastructure,…”
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Role of single-use gastroscopes in advanced endoscopy
Published in VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy (01-04-2024)“…[Display omitted]…”
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Topflight endoscopic submucosal dissection: a novel strategy for the resection of gastric fundus tumors
Published in VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy (01-12-2023)“…[Display omitted]…”
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