Search Results - "Pereira, Felipe V"

A natural bacterial-derived product, the metalloprotease arazyme, inhibits metastatic murine melanoma by inducing MMP-8 cross-reactive antibodies by Pereira, Felipe V, Ferreira-Guimarães, Carla A, Paschoalin, Thaysa, Scutti, Jorge A B, Melo, Filipe M, Silva, Luis S, Melo, Amanda C L, Silva, Priscila, Tiago, Manoela, Matsuo, Alisson L, Juliano, Luiz, Juliano, Maria A, Carmona, Adriana K, Travassos, Luiz R, Rodrigues, Elaine G

“…The increased incidence, high rates of mortality and few effective means of treatment of malignant melanoma, stimulate the search for new anti-tumor agents and…”
Get full text

FTY720 induces apoptosis in B16F10-NEX2 murine melanoma cells, limits metastatic development in vivo, and modulates the immune system by Pereira, Felipe V., Arruda, Denise C., Figueiredo, Carlos R., Massaoka, Mariana H., Matsuo, Alisson L., Bueno, Valquiria, Rodrigues, Elaine G.

“…Available chemotherapy presents poor control over the development of metastatic melanoma. FTY720 is a compound already approved by the Food and Drug…”
Get full text

α-Pinene isolated from Schinus terebinthifolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model by Matsuo, Alisson L., Figueiredo, Carlos R., Arruda, Denise C., Pereira, Felipe V., Borin Scutti, Jorge A., Massaoka, Mariana H., Travassos, Luiz R., Sartorelli, Patricia, Lago, João H.G.

“…► α-Pinene disrupts mitochondrial potential and induces apoptosis. ► Biochemical apoptotic hallmarks were evaluated in melanoma treated cells. ► The…”
Get full text

NLRP3 Inflammasome Mediates Aldosterone-Induced Vascular Damage by Bruder-Nascimento, Thiago, Ferreira, Nathanne S, Zanotto, Camila Z, Ramalho, Fernanda, Pequeno, Isabela O, Olivon, Vania C, Neves, Karla B, Alves-Lopes, Rheure, Campos, Eduardo, Silva, Carlos Alberto A, Fazan, Rubens, Carlos, Daniela, Mestriner, Fabiola L, Prado, Douglas, Pereira, Felipe V, Braga, Tarcio, Luiz, Joao Paulo M, Cau, Stefany B, Elias, Paula C, Moreira, Ayrton C, Câmara, Niels O, Zamboni, Dario S, Alves-Filho, Jose Carlos, Tostes, Rita C

“…BACKGROUND:Inflammation is a key feature of aldosterone-induced vascular damage and dysfunction, but molecular mechanisms by which aldosterone triggers…”
Get full text

Metformin exerts antitumor activity via induction of multiple death pathways in tumor cells and activation of a protective immune response by Pereira, Felipe V, Melo, Amanda Campelo L, Low, Jun Siong, de Castro, Íris Arantes, Braga, Tárcio T, Almeida, Danilo C, Batista de Lima, Ana Gabriela U, Hiyane, Meire I, Correa-Costa, Matheus, Andrade-Oliveira, Vinicius, Origassa, Clarice S T, Pereira, Rosana M, Kaech, Susan M, Rodrigues, Elaine G, Câmara, Niels Olsen S

“…The antitumor effect of metformin has been demonstrated in several types of cancer; however, the mechanisms involved are incompletely understood. In this…”
Get full text

Yield Curve as a Predictor of Recessions: Evidence from Panel Data by Ozturk, Huseyin, Pereira, Luis Felipe V. N.

“…In this study, we test empirically whether the slope of the yield curve-yield spread-is a good predictor of recessions. Although the convention in the…”
Get full text

Co-administration of α-GalCer analog and TLR4 agonist induces robust CD8+ T-cell responses to PyCS protein and WT-1 antigen and activates memory-like effector NKT cells by Coelho-dos-Reis, Jordana G, Huang, Jing, Tsao, Tiffany, Pereira, Felipe V, Funakoshi, Ryota, Nakajima, Hiroko, Sugiyama, Haruo, Tsuji, Moriya

“…Abstract In the present study, the combined adjuvant effect of 7DW8-5, a potent α-GalCer-analog, and MPLA, a TLR4 agonist, on the induction of vaccine-induced…”
Get full text

Accuracy of policy function approximations for strongly concave recursive problems by Maldonado, Wilfredo L., Candido, Osvaldo, Pereira, Luis Felipe V. N.

“…Under the hypotheses of strong concavity of the aggregator function and concavity of the stochastic operator which define the objective function of the…”
Get full text

Antitumor effect of chiral organotelluranes elicited in a murine melanoma model by Paschoalin, Thaysa, Martens, Adam A., Omori, Álvaro T., Pereira, Felipe V., Juliano, Luiz, Travassos, Luiz R., Machado-Santelli, Glaucia M., Cunha, Rodrigo L.O.R.

“…[Display omitted] Protease roles in cancer progression have been demonstrated and their inhibitors display antitumor effects. Cathepsins are lysosomal cysteine…”
Get full text

Interleukin-6 and the Gut Microbiota Influence Melanoma Progression in Obese Mice by Pereira, Felipe V., Melo, Amanda C. L., Silva, Marina B., de Melo, Filipe M., Terra, Fernanda F., Castro, Iris A., Perandini, Luiz A., Miyagi, Marcelli T., Sato, Fabio T., Origassa, Clarice S. T., Hiyane, Meire I., Donato, Jose, Wasinski, Frederick, Araujo, Ronaldo C., Festuccia, William T. L., da Silva, Joao Santana, Camara, Niels Olsen S.

“…There is a strong correlation between obesity and cancer. Here, we investigated the influence of IL-6 and gut microbiota of obese mice in melanoma development…”
Get full text

β-Actin-binding Complementarity-determining Region 2 of Variable Heavy Chain from Monoclonal Antibody C7 Induces Apoptosis in Several Human Tumor Cells and Is Protective against Metastatic Melanoma by Arruda, Denise C., Santos, Luana C.P., Melo, Filipe M., Pereira, Felipe V., Figueiredo, Carlos R., Matsuo, Alisson L., Mortara, Renato A., Juliano, Maria A., Rodrigues, Elaine G., Dobroff, Andrey S., Polonelli, Luciano, Travassos, Luiz R.

“…Complementarity-determining regions (CDRs) from monoclonal antibodies tested as synthetic peptides display anti-infective and antitumor activities, independent…”
Get full text

A cyclopalladated complex interacts with mitochondrial membrane thiol-groups and induces the apoptotic intrinsic pathway in murine and cisplatin-resistant human tumor cells by Serrano, Fabiana A, Matsuo, Alisson L, Monteforte, Priscila T, Bechara, Alexandre, Smaili, Soraya S, Santana, Débora P, Rodrigues, Tiago, Pereira, Felipe V, Silva, Luis S, Machado, Jr, Joel, Santos, Edson L, Pesquero, João B, Martins, Rafael M, Travassos, Luiz R, Caires, Antonio C F, Rodrigues, Elaine G

“…Systemic therapy for cancer metastatic lesions is difficult and generally renders a poor clinical response. Structural analogs of cisplatin, the most widely…”
Get full text

Anti‐metastatic immunotherapy based on mucosal administration of flagellin and immunomodulatory P10 by Melo, Filipe M, Braga, Catarina JM, Pereira, Felipe V, Maricato, Juliana T, Origassa, Clarice ST, Souza, Mariana F, Melo, Amanda C, Silva, Priscila, Tomaz, Samanta L, Gimenes, Karina P, Scutti, Jorge AB, Juliano, Maria A, Zamboni, Dario S, Câmara, Niels O, Travassos, Luiz R, Ferreira, Luis CS, Rodrigues, Elaine G

“…Current therapies against malignant melanoma generally fail to increase survival in most patients, and immunotherapy is a promising approach as it could reduce…”
Get full text

TLR4-mediated immunomodulatory properties of the bacterial metalloprotease arazyme in preclinical tumor models by Pereira, Felipe V., Melo, Amanda C. L., de Melo, Filipe M., Mourão-Sá, Diego, Silva, Priscila, Berzaghi, Rodrigo, Herbozo, Carolina C. A., Coelho-dos-Reis, Jordana, Scutti, Jorge A., Origassa, Clarice S. T., Pereira, Rosana M., Juliano, Luis, Juliano, Maria Aparecida, Carmona, Adriana K., Câmara, Niels O. S., Tsuji, Moriya, Travassos, Luiz R., Rodrigues, Elaine G.

“…Despite the recent approval of new agents for metastatic melanoma, its treatment remains challenging. Moreover, few available immunotherapies induce a strong…”
Get full text

Abstract 5296: The role of SOCS-1 in stimulating melanoma development through growth factor receptors and MAPK pathways by Berzaghi, Rodrigo, Pereira, Felipe V., Maia, Vera S.C., Scutti, Jorge B., Travassos, Luiz R.

“…Abstract Knowledge on the regulatory pathways involved in melanoma development and progression has advanced significantly in recent years. It is now recognized…”
Get full text

Pyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo by Figueiredo, Carlos R, Matsuo, Alisson L, Pereira, Felipe V, Rabaça, Aline N, Farias, Camyla F, Girola, Nátalia, Massaoka, Mariana H, Azevedo, Ricardo A, Scutti, Jorge A B, Arruda, Denise C, Silva, Luciana P, Rodrigues, Elaine G, Lago, João Henrique G, Travassos, Luiz R, Silva, Regildo M G

“…Pyrostegia venusta (Ker. Gawl.) Miers (Bignoniacea) is a medicinal plant from the Brazilian Cerrado used to treat leucoderma and common diseases of the…”
Get full text

A Natural Bacterial-Derived Product, the Metalloprotease Arazyme, Inhibits Metastatic Murine Melanoma by Inducing MMP-8 Cross-Reactive Antibodies: e96141 by Pereira, Felipe V, Ferreira-Guimaraes, Carla A, Paschoalin, Thaysa, Scutti, Jorge AB, Melo, Filipe M, Silva, Luis S, Melo, Amanda CL, Silva, Priscila, Tiago, Manoela, Matsuo, Alisson L

“…The increased incidence, high rates of mortality and few effective means of treatment of malignant melanoma, stimulate the search for new anti-tumor agents and…”
Get full text