Search Results - "Pereira, David M."

Tuning protein folding in lysosomal storage diseases: the chemistry behind pharmacological chaperones by Pereira, David M, Valentão, Patrícia, Andrade, Paula B

“…Misfolding of proteins is the basis of several proteinopathies. Chemical and pharmacological chaperones are small molecules capable of inducing the correct…”
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Pyrrolizidine Alkaloids: Chemistry, Pharmacology, Toxicology and Food Safety by Moreira, Rute, Pereira, David M, Valentão, Patrícia, Andrade, Paula B

“…Pyrrolizidine alkaloids (PA) are widely distributed in plants throughout the world, frequently in species relevant for human consumption. Apart from the…”
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Endoplasmic reticulum stress signaling in cancer and neurodegenerative disorders: Tools and strategies to understand its complexity by da Silva, Daniela Correia, Valentão, Patrícia, Andrade, Paula B., Pereira, David M.

“…[Display omitted] The endoplasmic reticulum (ER) comprises a network of tubules and vesicles that constitutes the largest organelle of the eukaryotic cell…”
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Phenolics: From Chemistry to Biology by Pereira, David M., Valentão, Patrícia, Pereira, José A., Andrade, Paula B.

“…In recent years, few classes of natural products have received as much attention as phenolics and polyphenols. This special issue of Molecules, “Phenolics and…”
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The Chemical Space of Terpenes: Insights from Data Science and AI by Hosseini, Morteza, Pereira, David M

“…Terpenes are a widespread class of natural products with significant chemical and biological diversity, and many of these molecules have already made their way…”
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Marine-Derived Anticancer Agents: Clinical Benefits, Innovative Mechanisms, and New Targets by Pereira, Renato B, Evdokimov, Nikolai M, Lefranc, Florence, Valentão, Patrícia, Kornienko, Alexander, Pereira, David M, Andrade, Paula B, Gomes, Nelson G M

“…The role of the marine environment in the development of anticancer drugs has been widely reviewed, particularly in recent years. However, the innovation in…”
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In silico and in vitro chemometrics, cell toxicity and permeability of naringenin 8-sulphonate and derivatives by Macedo, Tiago, Paiva-Martins, Fátima, Valentão, Patrícia, Pereira, David M

“…Sulphur containing natural compounds are among the most biologically relevant metabolites . Naringenin 8-sulphonate from Sabine was evaluated in a previous…”
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Essential Oils in Livestock: From Health to Food Quality by Nehme, Ralph, Andrés, Sonia, Pereira, Renato B, Ben Jemaa, Meriem, Bouhallab, Said, Ceciliani, Fabrizio, López, Secundino, Rahali, Fatma Zohra, Ksouri, Riadh, Pereira, David M, Abdennebi-Najar, Latifa

“…Using plant essential oils (EOs) contributes to the growing number of natural plants' applications in livestock. Scientific data supporting the efficacy of EOs…”
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New eugenol derivatives with enhanced insecticidal activity by Fernandes, Maria José Gomes, Pereira, Renato B., Pereira, David M., Fortes, A. Gil, Castanheira, Elisabete M. S., Gonçalves, M. Sameiro T.

“…Eugenol, the generic name of 4-allyl-2-methoxyphenol, is the major component of clove essential oil, and has demonstrated relevant biological potential with…”
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A Pipeline for Natural Small Molecule Inhibitors of Endoplasmic Reticulum Stress by Correia da Silva, Daniela, Valentão, Patrícia, Andrade, Paula B., Pereira, David M.

“…The homeostasis of eukaryotic cells is inseverable of that of the endoplasmic reticulum (ER). The main function of this organelle is the synthesis and folding…”
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Phytochemical Analysis and Antiproliferative Activity of Ulex gallii Planch. (Fabaceae), a Medicinal Plant from Galicia (Spain) by Bada, Lucía, Pereira, Renato B, Pereira, David M, Lores, Marta, Celeiro, María, Quezada, Elías, Uriarte, Eugenio, Gil-Longo, José, Viña, Dolores

“…The genus comprises thirteen accepted species of perennial shrubs in the family Fabaceae. In Galicia (Spain) many of these are considered spontaneous…”
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Essential Oil Stabilisation by Response Surface Methodology (RSM): Nanoemulsion Formulation, Physicochemical, Microbiological, and Sensory Investigations by BenJemaa, Mariem, Rahali, Fatma Zohra, Falleh, Hanen, Beji-Serairi, Raja, Megdiche-Ksouri, Wided, Hamrouni, Ibtissem, Hammami, Majdi, Nehme, Ralph, Pereira, Renato B., Andrés, Sonia, Bouhallab, Said, Pereira, David M., Ceciliani, Fabrizio, Abdennebi-Najar, Latifa, Ksouri, Riadh

“…This manuscript aimed to optimise the encapsulation of Thymus capitatus essential oil into nanoemulsion. Response Surface Methodology results were best fitted…”
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Anti-inflammatory effect of unsaturated fatty acids and Ergosta-7,22-dien-3-ol from Marthasterias glacialis: prevention of CHOP-mediated ER-stress and NF-κB activation by Pereira, David M, Correia-da-Silva, Georgina, Valentão, Patrícia, Teixeira, Natércia, Andrade, Paula B

“…There has been increasing awareness to the potential interest of drug discovery from marine natural products to treat several pathological conditions,…”
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Flavonoid Composition of Salacia senegalensis (Lam.) DC. Leaves, Evaluation of Antidermatophytic Effects, and Potential Amelioration of the Associated Inflammatory Response by Gomes, Nelson G M, Oliveira, Andreia P, Cunha, Diana, Pereira, David M, Valentão, Patrícia, Pinto, Eugénia, Araújo, Luísa, Andrade, Paula B

“…Predominantly spread in West Tropical Africa, the shrub (Lam.) DC. is known because of its medicinal properties, the leaves being used in the treatment of skin…”
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Eugenol β-amino/β-alkoxy alcohols with selective anticancer activity by Teixeira, Cláudia, Pereira, Renato B., Pinto, Nuno F. S., Coelho, Catarina M. M., Fernandes, Maria José G., Fortes, A. Gil, Gonçalves, M. Sameiro T., Pereira, David M.

“…Eugenol, 4-allyl-2-methoxyphenol, is the main constituent of clove essential oil and has demonstrated relevant biological activity, namely anticancer activity…”
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An injectable, naproxen-conjugated, supramolecular hydrogel with ultra-low critical gelation concentration-prepared from a known folate receptor ligand by Oliveira, Carlos B P, Veloso, Sérgio R S, Castanheira, Elisabete M S, Figueiredo, Pedro R, Carvalho, Alexandra T P, Hilliou, Loic, Pereira, Renato B, Pereira, David M, Martins, José A, Ferreira, Paula M T, Jervis, Peter J

“…Short peptides capped on the N-terminus with aromatic groups are often able to form supramolecular hydrogels-self-assembled networks of fibrils able to trap…”
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Discovery of the anticancer activity for lung and gastric cancer of a brominated coelenteramine analog by González-Berdullas, Patricia, Pereira, Renato B., Teixeira, Cláudia, Silva, José Pedro, Magalhães, Carla M., Rodríguez-Borges, José E., Pereira, David M., Silva, Joaquim C. G. Esteves da, Silva, Luís Pinto da

“…Supplementary Materials: The following supporting information can be downloaded at: https: //www.mdpi.com/article/10.3390/ijms23158271/s1. Cancer is still a…”
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Absolute configuration by vibrational circular dichroism of anti-inflammatory macrolide briarane diterpenoids from the Gorgonian Briareum asbestinum by Pech-Puch, Dawrin, Joseph-Nathan, Pedro, Burgueño-Tapia, Eleuterio, González-Salas, Carlos, Martínez-Matamoros, Diana, Pereira, David M., Pereira, Renato B., Jiménez, Carlos, Rodríguez, Jaime

“…The four new briarane diterpenoids 2-butyryloxybriarane B-3 ( 2 ), 9-acetylbriarenolide S ( 3 ), briarenolide W ( 4 ), and 12-isobriarenolide P ( 5 ), along…”
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Anti-Inflammatory Effects of 5α,8α-Epidioxycholest-6-en-3β-ol, a Steroidal Endoperoxide Isolated from Aplysia depilans , Based on Bioguided Fractionation and NMR Analysis by Pereira, Renato B, Pereira, David M, Jiménez, Carlos, Rodríguez, Jaime, Nieto, Rosa M, Videira, Romeu A, Silva, Olga, Andrade, Paula B, Valentão, Patrícia

“…Sea hares of genus are recognized as a source of a diverse range of metabolites. 5α,8α-Endoperoxides belong to a group of oxidized sterols commonly found in…”
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Application of natural pigments in ordinary cooked ham by Dias, Sandra, Castanheira, Elisabete M. S., Fortes, A. Gil, Pereira, David M., Rodrigues, Ana Rita Oliveira, Pereira, Regina, Gonçalves, M. Sameiro T.

“…The possibility of obtaining a carmine or pink color on ordinary cooked ham by applying natural dyes from three plant species, namely red radish ( Raphanus…”
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