Search Results - "Pereira, Cynthia Nathalia"
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Structural Optimization and Biological Activity of Pyrazole Derivatives: Virtual Computational Analysis, Recovery Assay and 3D Culture Model as Potential Predictive Tools of Effectiveness against Trypanosoma cruzi
Published in Molecules (Basel, Switzerland) (08-11-2021)“…Chagas disease, a chronic and silent disease caused by , is currently a global public health problem. The treatment of this neglected disease relies on…”
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Synthesis by Microwave Irradiation, Molecular Structural Analysis and Trypanocidal Activity of Novel Pyrazole-tetrahydropyrimidine Derivatives
Published in Current organic synthesis (01-01-2023)“…A series of new eight 2-(1-aryl-3-methyl-1H-pyrazol-4-yl)-1,4,5,6-tetrahydropyrimidines 1(a-h) were synthesized by microwave irradiation technique. In vitro…”
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Synthesis by microwave irradiation of new pyrazole-imidazoline-pyrimidine analogs: Physicochemical and photophysical properties and their biological activity against Trypanosoma cruzi
Published in Journal of molecular structure (15-10-2023)“…•Microwave irradiation is an important methodology to synthetize chemical compounds.•Chagas disease is a neglected tropical disease which is endemic in latin…”
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