Search Results - "Pereira, C. Filipe"
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CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression
Published in PLoS genetics (01-07-2010)“…CHD7 is one of nine members of the chromodomain helicase DNA-binding domain family of ATP-dependent chromatin remodeling enzymes found in mammalian cells. De…”
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Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators
Published in Nature cell biology (01-06-2010)“…Polycomb Repressor Complexes (PRCs) are important regulators of embryogenesis. In embryonic stem (ES) cells many genes that regulate subsequent stages in…”
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REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells
Published in Development (Cambridge) (01-03-2009)“…REST is a transcriptional repressor that targets a group of neuronal genes in non-neuronal cells. In embryonic stem (ES) cells, REST has been implicated in…”
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Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo
Published in Epigenetics & chromatin (12-01-2010)“…During early mouse development, two extra-embryonic lineages form alongside the future embryo: the trophectoderm (TE) and the primitive endoderm (PrE)…”
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Short RNAs Are Transcribed from Repressed Polycomb Target Genes and Interact with Polycomb Repressive Complex-2
Published in Molecular cell (11-06-2010)“…Polycomb proteins maintain cell identity by repressing the expression of developmental regulators specific for other cell types. Polycomb repressive complex-2…”
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CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell-Specific Gene Expression: e1001023
Published in PLoS genetics (01-07-2010)“…CHD7 is one of nine members of the chromodomain helicase DNA-binding domain family of ATP-dependent chromatin remodeling enzymes found in mammalian cells. De…”
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Journal Article