Search Results - "Pereira, Alberto M"
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Adrenal Insufficiency in Corticosteroids Use: Systematic Review and Meta-Analysis
Published in The journal of clinical endocrinology and metabolism (01-06-2015)“…Objective: We aimed to estimate pooled percentages of patients with adrenal insufficiency after treatment with corticosteroids for various conditions in a…”
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Clinical factors involved in the recurrence of pituitary adenomas after surgical remission: a structured review and meta-analysis
Published in Pituitary (01-03-2012)“…To study the currently available data of recurrence rates of functioning and nonfunctioning pituitary adenomas following surgical cure and to analyze…”
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3
The epidemiology of aggressive pituitary tumors (and its challenges)
Published in Reviews in endocrine & metabolic disorders (01-06-2020)“…Pituitary tumors are not rare if prevalence rates from autopsy or radiological series are considered; approximately 0.5% of all pituitary adenomas will come to…”
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Surgery as a Viable Alternative First-Line Treatment for Prolactinoma Patients. A Systematic Review and Meta-Analysis
Published in The journal of clinical endocrinology and metabolism (01-03-2020)“…Abstract Context The improved remission and complication rates of current transsphenoidal surgery warrant reappraisal of the position of surgery as a viable…”
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Mortality in patients with Cushing's disease more than 10 years after remission: a multicentre, multinational, retrospective cohort study
Published in The lancet. Diabetes & endocrinology (01-07-2016)“…Summary Background No agreement has been reached on the long-term survival prospects for patients with Cushing's disease. We studied life expectancy in…”
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6
Effectiveness of medical treatment for Cushing’s syndrome: a systematic review and meta-analysis
Published in Pituitary (01-12-2018)“…Purpose To systematically review the effectiveness of medical treatment for Cushing’s syndrome in clinical practice, regarding cortisol secretion, clinical…”
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Improvement in Symptoms and Health-Related Quality of Life in Acromegaly Patients: A Systematic Review and Meta-Analysis
Published in The journal of clinical endocrinology and metabolism (01-02-2021)“…Abstract Background Whereas biochemical response is often used as a primary study outcome, improvement in symptoms and health-related quality of life (HRQoL)…”
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MANAGEMENT OF ENDOCRINE DISEASE: Mortality remains increased in Cushing's disease despite biochemical remission: a systematic review and meta-analysis
Published in European journal of endocrinology (01-04-2015)“…The aim of this systematic review and meta-analysis was to investigate whether mortality is increased in patients biochemically cured after initial treatment…”
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Recurrence of Hyperprolactinemia after Withdrawal of Dopamine Agonists: Systematic Review and Meta-Analysis
Published in The journal of clinical endocrinology and metabolism (01-01-2010)“…Context: Dopamine agonists are the treatment of choice for prolactinomas and symptomatic idiopathic hyperprolactinemia. However, the optimal treatment strategy…”
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Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma
Published in European journal of endocrinology (01-12-2009)“…ObjectiveTreatment options for patients with radioactive iodine (RaI) refractory metastases of differentiated thyroid carcinoma (DTC) are limited. We studied…”
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IGSF1 Deficiency Results in Human and Murine Somatotrope Neurosecretory Hyperfunction
Published in The journal of clinical endocrinology and metabolism (01-03-2020)“…Abstract Context The X-linked immunoglobulin superfamily, member 1 (IGSF1), gene is highly expressed in the hypothalamus and in pituitary cells of the POU1F1…”
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12
Effects of Long-Term Endogenous Corticosteroid Exposure on Brain Volume and Glial Cells in the AdKO Mouse
Published in Frontiers in neuroscience (10-02-2021)“…Chronic exposure to high circulating levels of glucocorticoids has detrimental effects on health, including metabolic abnormalities, as exemplified in…”
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13
Gene expression changes in the brain of a Cushing's syndrome mouse model
Published in Journal of neuroendocrinology (01-04-2022)“…Excess glucocorticoid exposure affects emotional and cognitive brain functions. The extreme form, Cushing's syndrome, is adequately modelled in the AdKO2.0…”
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14
Central serous chorioretinopathy in active endogenous Cushing’s syndrome
Published in Scientific reports (02-02-2021)“…Multiple case series have provided evidence for a relatively high incidence of central serous chorioretinopathy (CSC) in patients with active Cushing’s…”
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15
An Activating Mutation in the Kinase Homology Domain of the Natriuretic Peptide Receptor-2 Causes Extremely Tall Stature Without Skeletal Deformities
Published in The journal of clinical endocrinology and metabolism (01-12-2013)“…Background: C-type natriuretic peptide (CNP)/natriuretic peptide receptor 2 (NPR2) signaling is essential for long bone growth. Enhanced CNP production caused…”
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Pituitary Dysfunction in Adult Patients after Cranial Radiotherapy: Systematic Review and Meta-Analysis
Published in The journal of clinical endocrinology and metabolism (01-08-2011)“…Context: Cranial radiotherapy is an important cause of hypopituitarism. The prevalence of hypopituitarism varies considerably between studies. Objective: We…”
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Smaller grey matter volumes in the anterior cingulate cortex and greater cerebellar volumes in patients with long-term remission of Cushing's disease: a case–control study
Published in European journal of endocrinology (01-12-2013)“…ObjectivePatients with long-term remission of Cushing's disease (CD) have persistent psychological and cognitive impairments. It is unknown whether, and to…”
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Microscopic versus endoscopic transsphenoidal surgery in the Leiden cohort treated for Cushing's disease: surgical outcome, mortality, and complications
Published in Orphanet journal of rare diseases (11-03-2019)“…First-choice treatment for Cushing's disease is transsphenoidal adenomectomy. Since its introduction in the 1970s, many centers have now switched from…”
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Peripheral glucocorticoid receptor antagonism by relacorilant with modest HPA axis disinhibition
Published in Journal of endocrinology (01-02-2023)“…Glucocorticoid stress hormones are produced in response to hypothalamic–pituitary–adrenal (HPA) axis activation. Glucocorticoids are essential for physiology…”
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Negative illness perceptions are associated with impaired quality of life in patients after long-term remission of Cushing's syndrome
Published in European journal of endocrinology (01-10-2011)“…ObjectiveIllness perceptions pertain to the pattern of beliefs patients develop about their illness. Illness perceptions are determinants of quality of life…”
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