Search Results - "Perantoni, A O"

miR-23b targets proline oxidase, a novel tumor suppressor protein in renal cancer by Liu, W, Zabirnyk, O, Wang, H, Shiao, Y-H, Nickerson, M L, Khalil, S, Anderson, L M, Perantoni, A O, Phang, J M

“…Proline oxidase (POX) is a novel mitochondrial tumor suppressor that can suppress proliferation and induce apoptosis through the generation of reactive oxygen…”
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Serine-phosphorylated STAT1 is a prosurvival factor in Wilms' tumor pathogenesis by TIMOFEEVA, O. A, PLISOV, S, EVSEEV, A. A, PENG, S, JOSE-KAMPFNER, M, LOVVORN, H. N, DOME, J. S, PERANTONI, A. O

“…Wilms' tumor (WT), one of the most common pediatric solid cancers, arises in the developing kidney as a result of genetic and epigenetic changes that lead to…”
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Nitric oxide prodrug JS-K inhibits ubiquitin E1 and kills tumor cells retaining wild-type p53 by Kitagaki, J, Yang, Y, Saavedra, J E, Colburn, N H, Keefer, L K, Perantoni, A O

“…Nitric oxide (NO) is a major effector molecule in cancer prevention. A number of studies have shown that NO prodrug JS-K ( O 2 -(2,4-dinitrophenyl)…”
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Basic Fibroblast Growth Factor can Mediate the Early Inductive Events in Renal Development by Perantoni, Alan O., Dove, Lee F., Karavanova, Irina

“…The earliest characterized events during induction of tubulogenesis in renal anlage include the condensation or compaction of metanephrogenic mesenchyme with…”
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K-ras activation in premalignant and malignant epithelial lesions of the human uterus by ENOMOTO, T, INOUE, M, PERANTONI, A. O, BUZARD, G. S, MIKI, H, TANIZAWA, O, RICE, J. M

“…We previously reported (Cancer Res., 50:6139-6145, 1990) a significant frequency of activating point mutations in codon 12 of the K-ras oncogene in endometrial…”
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Activated neu Oncogene Sequences in Primary Tumors of the Peripheral Nervous System Induced in Rats by Transplacental Exposure to Ethylnitrosourea by Perantoni, Alan O., Rice, Jerry M., Reed, Carl D., Watatani, Masahiro, Wenk, Martin L.

“…Neurogenic tumors were selectively induced in high incidence in F344 rats by a single transplacental exposure to the direct-acting alkylating agent…”
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Epidermal growth factor and transforming growth factor-α-associated overexpression of cyclin D1, Cdk4, and c-Myc during hepatocarcinogenesis in Helicobacter hepaticus-infected A/JCr mice by RAMLJAK, D, JONES, A. B, DIWAN, B. A, PERANTONI, A. O, HOCHADEL, J. F, ANDERSON, L. M

“…Helicobacter hepaticus is a new bacterial species that is homologous to Helicobacter pylori, a human gastric carcinogen. H. hepaticus causes chronic active…”
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K-ras activation in gastric epithelial tumors in Japanese by Miki, H, Ohmori, M, Perantoni, A O, Enomoto, T

“…Point mutation in codons 12, 13 and 61 of the K-ras oncogene in gastric epithelial tumors were investigated by polymerase chain reaction from sections of…”
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TGF beta 2, LIF and FGF2 cooperate to induce nephrogenesis by Plisov, S Y, Yoshino, K, Dove, L F, Higinbotham, K G, Rubin, J S, Perantoni, A O

“…The metanephric kidney develops from interactions between the epithelial ureteric bud and adjacent metanephric mesenchyme, which is induced by the bud to form…”
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Renal development: perspectives on a Wnt-dependent process by Perantoni, Alan O

“…Specification of embryonic progenitors to generate the branched collecting duct system and tubular epithelia of the nephron in the metanephros is mediated by…”
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Mutation patterns in non-ras oncogenes and tumour suppressor genes in experimentally induced tumours by Perantoni, A O, Rice, J M

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Activation of neu by missense point mutation in the transmembrane domain in schwannomas induced in C3H/HeNCr mice by transplacental exposure to N-nitrosoethylurea by BUZARD, G. S, ENOMOTO, T, ANDERSON, L. M, PERANTONI, A. O, DEVOR, D. E, RICE, J. M

“…Transplacentally initiated schwannomas in mice and rats arise preferentially in the Gasserian ganglion of the trigeminal nerve and spinal root ganglia, while…”
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neu mutation in schwannomas induced transplacentally in Syrian golden hamsters by N-nitrosoethylurea : high incidence but low allelic representation by BUZARD, G. S, ENOMOTO, T, HONGYO, T, PERANTONI, A. O, DIWAN, B. A, DEVOR, D. E, REED, C. D, DOVE, L. F, RICE, J. M

“…Peripheral nerve tumors (PNT) and melanomas induced transplacentally on day 14 of gestation in Syrian golden hamsters by N-nitrosoethylurea were analyzed for…”
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Variant mutational activation of the K-ras oncogene in renal mesenchymal tumors induced in newborn F344 rats by methyl(methoxymethyl)nitrosamine by Higinbotham, Kathleen G., Rice, Jerry M., Reed, Carl D., Watatani, Masahiro, Enomoto, Takayuki, Anderson, Lucy M., Perantoni, Alan O.

“…Renal mesenchymal tumors were induced at high incidence in F344 rats by a single intraperitoneal injection of methyl(methoxymethyl)nitrosamine (DMN-OMe) within…”
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Infrequent activation of K-ras, H-ras, and other oncogenes in hepatocellular neoplasms initiated by methyl(acetoxymethyl)nitrosamine, a methylating agent, and promoted by phenobarbital in F344 rats by WATATANI, M, PERANTONI, A. O, REED, C. D, ENOMOTO, T, WENK, M. L, RICE, J. M

“…Fischer 344/Ncr rats of both sexes were subjected to partial hepatectomy and then initiated 21-24 h later by a single injection of…”
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Comparative immunohistochemical reactivity of monoclonal and polyclonal antibodies to H-ras p21 in normal and neoplastic tissues of rodents and humans by Ward, J M, Perantoni, A O, Santos, E

“…Five mouse monoclonal antibodies (mES 2, 4, 8, 13 and 20) produced against bacterially expressed BALB ras p21 and five other monoclonal or polyclonal…”
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Induction of tubules in rat metanephrogenic mesenchyme in the absence of an inductive tissue by Perantoni, A O, Dove, L F, Williams, C L

“…Differentiation of metanephrogenic mesenchyme to renal tubular epithelium requires induction by the ureteric bud in vivo or any of several embryonic tissues in…”
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H-ras activation and ras p21 expression in bladder tumors induced in F344/NCr rats by N-butyl-N-(4-hydroxybutyl)nitrosamine by Enomoto, T, Ward, J M, Perantoni, A O

“…Bladder tumors were induced in male F344/NCr rats by administration of N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) at 500 p.p.m. in their drinking water for 12…”
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Conditioned medium from a rat ureteric bud cell line in combination with bFGF induces complete differentiation of isolated metanephric mesenchyme by Karavanova, I D, Dove, L F, Resau, J H, Perantoni, A O

“…Differentiation of metanephric mesenchyme is triggered by an inductive signal(s) from the epithelial ureteric bud. As a result of this induction, most of the…”
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Infrequent transforming mutations in the transmembrane domain of the neu oncogene in spontaneous rat schwannomas by Perantoni, A O, Turusov, V S, Buzard, G S, Rice, J M

“…Ethylnitrosourea (ENU) given transplacentally to rats induces schwannomas of the cranial, spinal, and peripheral nerves, with a high frequency of mutations in…”
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