Search Results - "Peralta Álvarez, Marco Polo"

Precision medicine and its implementation in patients with NTRK fusion genes: perspective from developing countries by Cardona, Andrés F., Arrieta, Oscar, Ruiz-Patiño, Alejandro, Sotelo, Carolina, Zamudio-Molano, Nataly, Zatarain-Barrón, Zyanya Lucia, Ricaurte, Luisa, Raez, Luis, Álvarez, Marco Polo Peralta, Barrón, Feliciano, Rojas, Leonardo, Rolfo, Christian, Karachaliou, Niki, Molina-Vila, Miguel Angel, Rosell, Rafael

“…Precision oncology is the field that places emphasis on the diagnosis and treatment of tumors that harbor specific genomic alterations susceptible to…”
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Induction of Functional Specific Antibodies, IgG-Secreting Plasmablasts and Memory B Cells Following BCG Vaccination by Bitencourt, Julia, Peralta-Álvarez, Marco Polo, Wilkie, Morven, Jacobs, Ashley, Wright, Daniel, Salman Almujri, Salem, Li, Shuailin, Harris, Stephanie A, Smith, Steven G, Elias, Sean C, White, Andrew D, Satti, Iman, Sharpe, Sally S, O'Shea, Matthew K, McShane, Helen, Tanner, Rachel

“…Tuberculosis (TB) is a major global health problem and the only currently-licensed vaccine, BCG, is inadequate. Many TB vaccine candidates are designed to be…”
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Safety of a controlled human infection model of tuberculosis with aerosolised, live-attenuated Mycobacterium bovis BCG versus intradermal BCG in BCG-naive adults in the UK: a dose-escalation, randomised, controlled, phase 1 trial by Satti, Iman, Marshall, Julia L, Harris, Stephanie A, Wittenberg, Rachel, Tanner, Rachel, Lopez Ramon, Raquel, Wilkie, Morven, Ramos Lopez, Fernando, Riste, Michael, Wright, Daniel, Peralta Alvarez, Marco Polo, Williams, Nicola, Morrison, Hazel, Stylianou, Elena, Folegatti, Pedro, Jenkin, Daniel, Vermaak, Samantha, Rask, Linnea, Cabrera Puig, Ingrid, Powell Doherty, Rebecca, Lawrie, Alison, Moss, Paul, Hinks, Timothy, Bettinson, Henry, McShane, Helen

“…Mycobacterium tuberculosis is the main causative agent of tuberculosis. BCG, the only licensed vaccine, provides inadequate protection against pulmonary…”
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Low-dose M.tb infection but not BCG or MTBVAC vaccination enhances heterologous antibody titres in non-human primates by Peralta Alvarez, Marco Polo, Jones, Holly, Redondo Azema, Hugo, Davis, Chloe, White, Andrew D, Sarfas, Charlotte, Dennis, Mike, Li, Shuailin, Wright, Daniel, Puentes, Eugenia, Kimuda, Simon, Belij-Rammerstorfer, Sandra, Aguilo, Nacho, Martin, Carlos, Sharpe, Sally, McShane, Helen, Tanner, Rachel

“…Mycobacteria are known to exert a range of heterologous effects on the immune system. The mycobacteria-based Freund's Complete Adjuvant is a potent…”
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Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002) by Aboagye, Jeremy, Aley, Parvinder K, Angus, Brian, Belij-Rammerstorfer, Sandra, Bittaye, Mustapha, Davies, Sophie, Dejnirattisai, Wanwisa, Ewer, Katie J, Folegatti, Pedro M, Fowler, Jamie, Hill, Adrian V S, Kerridge, Simon, Mujadidi, Yama F, Plested, Emma, Robinson, Hannah, Sheehan, Emma, Smith, Holly, Woods, Danielle, Screaton, Gavin, Gilbert, Sarah C, Lambe, Teresa, Adlou, Syed, Aley, Robert, Ali, Aabidah, Baker, Phillip, Barrett, Jordan R., Beadon, Kirsten, Beckley, Rebecca, Bellamy, Duncan, Beveridge, Amy, Blackwell, Luke, Bridges-Webb, Alice, Brown, Charlie, Collins, Andrea M., Crocker, Wendy E.M., Davies, Hannah, Davies, Judith, Demissie, Tesfaye, Di Maso, Claudio, Dinesh, Tanya, Donnellan, Francesca R., Drake-Brockman, Rachael, Duncan, Christopher J.A., Emary, Katherine R.W., Ferreira, Daniela, Finn, Adam, Francis, Emma, Fuskova, Michelle, Galiza, Eva, Green, Christopher A., Harrison, Daisy, Hawkins, Sophia, Heath, Paul T., Horsington, Bryn, Jones, Elizabeth, Kasanyinga, Mwila, Kerr, David, Kinch, Jasmin, Koleva, Stanislava, Kwok, Jonathan, Lawrie, Alison M., Li, Grace, Libri, Vincenzo, Lopez Ramon, Raquel, Makinson, Rebecca, Mazur, Olga, McGregor, Alastair C., Muller, Jilly, Mweu, Philomena, Noristani, Rabiullah, Polo Peralta Alvarez, Marco, Platt, Abigail, Pollock, Katrina M., Poulton, Ian, Provstgaard-Morys, Samuel, Pulido-Gomez, David, Rajan, Matthew, Ramos Lopez, Fernando, Roberts, Hannah, Rudiansyah, Indra, Sanders, Katherine, Saunders, Jack E., Seddiqi, Samiullah, Shaw, Robert, Silva-Reyes, Laura, Smith, Andrew, Spencer, Alexandra J., Stuart, Arabella S.V., Sutherland, Rebecca, Tang, Karly, Thomas, Tonia M., Thomson, Emma C., Török, Estée M., Toshner, Mark, Turnbull, Iain, Vichos, Iason, Whelan, Conor, Williams, Christopher J.A., Wright, Daniel, Yao, Andy

“…COVID-19 vaccine supply shortages are causing concerns about compromised immunity in some countries as the interval between the first and second dose becomes…”
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Efficacy and Safety of Pembrolizumab Plus Docetaxel vs Docetaxel Alone in Patients With Previously Treated Advanced Non-Small Cell Lung Cancer: The PROLUNG Phase 2 Randomized Clinical Trial by Arrieta, Oscar, Barrón, Feliciano, Ramírez-Tirado, Laura Alejandra, Zatarain-Barrón, Zyanya Lucia, Cardona, Andrés F, Díaz-García, Diego, Yamamoto Ramos, Masao, Mota-Vega, Beatriz, Carmona, Amir, Peralta Álvarez, Marco Polo, Bautista, Yolanda, Aldaco, Fernando, Gerson, Raquel, Rolfo, Christian, Rosell, Rafael

“…Because of socioeconomic factors, many patients with advanced non-small cell lung cancer (NSCLC) do not receive immunotherapy in the first-line setting. It is…”
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Simian adenovirus vector production for early-phase clinical trials: A simple method applicable to multiple serotypes and using entirely disposable product-contact components by Fedosyuk, Sofiya, Merritt, Thomas, Peralta-Alvarez, Marco Polo, Morris, Susan J, Lam, Ada, Laroudie, Nicolas, Kangokar, Anilkumar, Wright, Daniel, Warimwe, George M, Angell-Manning, Phillip, Ritchie, Adam J, Gilbert, Sarah C, Xenopoulos, Alex, Boumlic, Anissa, Douglas, Alexander D

“…A variety of Good Manufacturing Practice (GMP) compliant processes have been reported for production of non-replicating adenovirus vectors, but important…”
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The use of immunotherapy for the treatment of tuberculosis by Ramos-Espinosa, Octavio, Islas-Weinstein, León, Peralta-Álvarez, Marco Polo, López-Torres, Manuel Othoniel, Hernández-Pando, Rogelio

“…Tuberculosis (TB) is the first cause of mortality by a single infectious agent in the world, causing more than one million deaths worldwide as reported by the…”
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Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK by Voysey, Merryn, Weckx, Lily Y, Collins, Andrea M, Hill, Helen, Lazarus, Rajeka, Lawrie, Alison M, McGregor, Alastair, Villafana, Tonya L, Gilbert, Sarah C, Aban, Marites, Aboagye, Jeremy, Adam, Matthew, Adams, Kirsty, Alves, Mariana P.S., Barnes, Eleanor, Berrie, Eleanor, Bewley, Kevin R., Bletchly, Heather, Borthwick, Nicola, Brown, Phillip, Buttigieg, Karen R., Cashen, Paul, Castro, Lucia Carratala, Chadwick, Jim, Chapman, David, Charlton, Sue, Clark, Matthew, Clutterbuck, Elizabeth A., Cooper, Cushla, Cooper, Rachel, Darroch, Paula, Dearlove, David, Drake-Brockman, Rachael, van Eck, Samual, Farrar, Madi, Fraiman, Pedro H.A., Gracie, Lara, Grossi, Leonardo, Hanrath, Aidan T., Harris, Tara, Hassan, Shadin, Hay, Jodie, Head, Ian, Hodges, Gina, Horne, Elizea, Hou, Mimi M., Humphries, Holly E., Hyder-Wright, Angela, Jeffers, Helen, Karampatsas, Konstantinos, Keen, Jade, Khan, Liaquat, King, Thomas B., Klenerman, Paul, Lees, Emily A., Li, Yuanyuan, Loew, Lisa, Marques, Gabriela N., Masilela, Mduduzi, Mathew, Moncy, Meijs, Wilma, Morris, Susan, Mpelembue, Mushiya, Noal, Helena, Nugent, Fay L., O'Connor, Daniel, Olchawski, Victoria, O'Reilly, Paula, Phillips, Daniel J., Pickup, Lorinda, Du Plessis, Joan, Pollard, Samuel, Poulton, Ian, Pulido, David, Reiné, Jesús, Resuello-Dauti, Mila, Richter, Alex, Roche, Sophie, Rollier, Christine, Ruiz, Sarah, Sala, Claudia, Sanchez-Gonzalez, Amada, Sharpe, Hannah E., Smith, Daniel C., Smith, Holly E., Soares, Tiago, Souza, Cinthia M.C.D.L., Spina, Fernanda, Steven, Jill, Stockdale, Lisa, Stockwell, Lisa V., Sturdy, Ann, Tarr, Alexander W., Taylor, Ursula, Themistocleous, Andreas, Tsheko, Betty Lebogang, Turabi, Aadil, Waddington, Claire S., Wallis, Erica, Webb, Stewart

“…A safe and efficacious vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the…”
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Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial by Aley, Parvinder K, Clutterbuck, Elizabeth A, Dold, Christina, Heath, Paul, Makinson, Rebecca, Pollock, Katrina M, Ramasamy, Maheshi, Robinson, Hannah, Douglas, Alexander D, Lambe, Teresa, Aboagye, Jeremy, Allen, Elizabeth, Anslow, Rachel, Baker, Philip, Bates, Louise, Batten, Alexander, Berry, Lisa, Beveridge, Amy, Bingham, Tracey, Brunt, Emily, Burbage, Jamie, Carroll, Miles W., Coombes, Naomi S., Cooper, Rachel, Crocker, Wendy E.M., Di Maso, Claudio, Dong, Tao, Douglas, Naomi, Downing, Charlotte, Elias, Sean C., Emary, Katherine R.W., Fletcher, Clare, Ford, Karen J., Fox, Polly, Frater, John, Galiza, Eva, Godwin, Kerry, Gorini, Giacomo, Goulston, Lyndsey, Gracie, Lara, Halwe, Sandro, Hamilton, Elizabeth, Hamlyn, Joseph, Harding, Irasha, Head, Ian, Hodgson, Susanne H.C., Howell, Nicola, Isitt, Catherine, Kailath, Reshma, Karampatsas, Konstantinos, Kerridge, Simon, Khan, Uzma, Kingham-Page, Lucy, Knott, Daniel, Koleva, Stanislava, Kupke, Alexandra, Lawrie, Alison M., Lee, Arlene, Lees, Emily A, Lias, Amelia M., Linder, Aline, Lopez Ramon, Raquel, Marlow, Emma, Marshall, Julia L., Meddaugh, Gretchen, Moore, Maria, Moran, Edward, Morris, Susan Jane, Morshead, Gertraud, Muller, Jilly, Munro, Alasdair, Noé, Andrés, O'Brien, Katie, O'Connor, Daniel, Oguti, Blanché, Oliver, Jennifer L., Osborn, Mairead, Pacurar, Mihaela, Pearce, Jennifer, Pfafferott, Katja, Poulton, Ian, Riddell, Amy, Sajjad, Sara, Sanders, Helen, Sanders, Katherine, Selby, Beatrice, Shelton, Holly, Song, Rinn, Stefanova, Elena, Tait, Moira, Talbot, Helen, Themistocleous, Yrene, Thomas, Merin, Towner, James, Turkentine, Kate, Turner, Sally, Veighey, Kristin, Vichos, Iason, Worth, Andrew T., Yau, Yasmine

“…The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might be curtailed by vaccination. We assessed the safety, reactogenicity, and…”
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Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials by Voysey, Merryn, Weckx, Lily Y, Collins, Andrea M, Feng, Shuo, Marshall, Richard P, Milan, Eveline P, Pollock, Katrina M, Ramasamy, Maheshi N, Robinson, Hannah, Andrade, Claudia Sala, Barker, Debbie, Bates, Louise, Batten, Alexander, Berzenyi, Daniella, Bird, Adam, Blundell, Susannah R., Budd, William, Cabrera Puig, Ingrid, Calvert, Anna, Carvalho, Yasmin de M., Castro, Thais R.Y., Chiplin, Emily, Cifuentes, Liliana, Danos, Zsofia, Dantas, Maria T.D.C., Davies, Sophie, Desai, Amisha, Drake-Brockman, Rachael, Edwards, Mandy, Edwards, Nick J., El Muhanna, Omar M., Ellison-Handley, Branwen, Fedosyuk, Sofiya, Fisher, Richard, Fofie, Hazel, Franco, Marilia M., Fuskova, Michelle, Godwin, Kerry, Gokani, Karishma, Gonçalves, Maria Luisa Freire, Goodall, Jack, Harris-Wright, Tara A., Howell, Nicola, Humphreys, Jonathan, Iyer, Vidyashankara, Jackson, Susan, Jaumdally, Shameem, Jorge, Marianna Rocha, Kellett Wright, Johanna, Kelly, Elizabeth J., Kelly, Dearbhla M., Kidd, Sarah, Larwood, Jessica P.J., Lees, Emily A., Lelliott, Alice, Leung, Stephanie, Manning, Nicola, Mazur, Olga, McGlashan, Joanna, Megson, Clare, Mesquita, Ana Carolina F., Mitton, Celia, Morrison, Hazel, Morselli, Franca, Oliveira, Catarina, Oosthuizen, Angela, Owen, David R.J., Parracho, Helena M. R.T., Perez, Ana Luiza, Perinpanathan, Tanaraj, Perumal, Rubeshan, Plank, Mary, Proud, Pamela C., Rajeswaran, Thurkka, Rees, Byron, Rhead, Sarah, Richards, Alexander, Roberts, Hannah, Robinson, Ryan E., Rudiansyah, Indra, Saunders, Jack E., Screaton, Gavin R., Sorley, Kim, Spencer, Alexandra J., Spoors, Louise, Stein, Ricardo, Strickland, Louise H., Sturdy, Ann, Sutton, Natalina, Taoushanis, Carol, Thomas, Merin, Tinoco, Lygia Accioly, Tomic, Adriana, Truby, Adam, Underwood, Benjamin R., Vichos, Iason, Watkins, Bridget, Wellbelove, Zoe, White, Caroline, Willingham, Silvia

“…The ChAdOx1 nCoV-19 (AZD1222) vaccine has been approved for emergency use by the UK regulatory authority, Medicines and Healthcare products Regulatory Agency,…”
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Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses by Barrett, Jordan R., Belij-Rammerstorfer, Sandra, Dold, Christina, Ewer, Katie J., Folegatti, Pedro M., Gilbride, Ciaran, Halkerston, Rachel, Hill, Jennifer, Jenkin, Daniel, Stockdale, Lisa, Verheul, Marije K., Aley, Parvinder K., Angus, Brian, Bellamy, Duncan, Berrie, Eleanor, Bibi, Sagida, Bittaye, Mustapha, Carroll, Miles W., Cavell, Breeze, Clutterbuck, Elizabeth A., Edwards, Nick, Flaxman, Amy, Fuskova, Michelle, Gorringe, Andrew, Hallis, Bassam, Kerridge, Simon, Lawrie, Alison M., Linder, Aline, Liu, Xinxue, Madhavan, Meera, Makinson, Rebecca, Mellors, Jack, Minassian, Angela, Moore, Maria, Mujadidi, Yama, Plested, Emma, Poulton, Ian, Ramasamy, Maheshi N., Robinson, Hannah, Rollier, Christine S., Song, Rinn, Snape, Matthew D., Tarrant, Richard, Taylor, Stephen, Thomas, Kelly M., Voysey, Merryn, Watson, Marion E. E., Wright, Daniel, Douglas, Alexander D., Green, Catherine M., Hill, Adrian V. S., Lambe, Teresa, Gilbert, Sarah, Pollard, Andrew J.

“…More than 190 vaccines are currently in development to prevent infection by the novel severe acute respiratory syndrome coronavirus 2. Animal studies suggest…”
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Intravenous BCG vaccination in non-human primates induces superior serum antibody titers with enhanced avidity and opsonizing capacity compared to the intradermal route by Peralta Alvarez, Marco Polo, Downward, Keya, White, Andrew, Harris, Stephanie A., Satti, Iman, Li, Shuailin, Morrison, Alexandra, Sibley, Laura, Sarfas, Charlotte, Dennis, Mike, Azema, Hugo Redondo, Sharpe, Sally, McShane, Helen, Tanner, Rachel

“…A new and more effective tuberculosis (TB) vaccine is urgently needed, but development is hampered by the lack of validated immune correlates of protection…”
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