Search Results - "Peradziryi, Hanna"
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PTK7 localization and protein stability is affected by canonical Wnt ligands
Published in Journal of cell science (01-06-2017)“…Protein tyrosine kinase 7 (PTK7) is an evolutionarily conserved transmembrane receptor with important roles in embryonic development and disease. Originally…”
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Cell-state transitions and collective cell movement generate an endoderm-like region in gastruloids
Published in eLife (11-04-2022)“…Shaping the animal body plan is a complex process that involves the spatial organization and patterning of the different germ layers. Recent advances in live…”
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Evolutionary origin of vertebrate OCT4/POU5 functions in supporting pluripotency
Published in Nature communications (21-09-2022)“…The support of pluripotent cells over time is an essential feature of development. In eutherian embryos, pluripotency is maintained from naïve states in…”
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A Conserved Oct4/POUV-Dependent Network Links Adhesion and Migration to Progenitor Maintenance
Published in Current biology (18-11-2013)“…The class V POU domain transcription factor Oct4 (Pou5f1) is a pivotal regulator of embryonic stem cell (ESC) self-renewal and reprogramming of somatic cells…”
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The many roles of PTK7: A versatile regulator of cell–cell communication
Published in Archives of biochemistry and biophysics (01-08-2012)“…► Wnt co-receptors decide Wnt signaling outcome. ► Wnt co-receptor PTK7 regulates planar cell polarity. ► Wnt co-receptor PTK7 turns off canonical Wnt…”
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PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling
Published in The EMBO journal (14-09-2011)“…Wnt signalling is an evolutionarily conserved pathway that directs cell‐fate determination and morphogenesis during metazoan development. Wnt ligands are…”
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PlexinA1 interacts with PTK7 and is required for neural crest migration
Published in Biochemical and biophysical research communications (12-11-2010)“…► PlexinA1 is expressed in migrating neural crest cells in Xenopus laevis. ► Loss of function data shows that PlexinA1 is required for neural crest migration…”
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PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling: PTK7/Otk interacts with Wnts
Published in The EMBO journal (14-09-2011)Get full text
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