Search Results - "Peradze, Natia"

Leptin alters energy intake and fat mass but not energy expenditure in lean subjects by Chrysafi, Pavlina, Perakakis, Nikolaos, Farr, Olivia M., Stefanakis, Konstantinos, Peradze, Natia, Sala-Vila, Aleix, Mantzoros, Christos S.

“…Based on studies in mice, leptin was expected to decrease body weight in obese individuals. However, the majority of the obese are hyperleptinemic and do not…”
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Short-term treatment with high dose liraglutide improves lipid and lipoprotein profile and changes hormonal mediators of lipid metabolism in obese patients with no overt type 2 diabetes mellitus: a randomized, placebo-controlled, cross-over, double-blind clinical trial by Peradze, Natia, Farr, Olivia M, Perakakis, Nikolaos, Lázaro, Iolanda, Sala-Vila, Aleix, Mantzoros, Christos S

“…Long-term treatment with up to 1.8 mg liraglutide improves cardiovascular and all-cause mortality in patients with type 2 diabetes at high risk for…”
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Viral load and disease severity in COVID-19 by Pawar, Rahul Dnyaneshwar, Balaji, Lakshman, Mehta, Shivani, Cole, Andrew, Liu, Xiaowen, Peradze, Natia, Grossestreuer, Anne Victoria, Issa, Mahmoud Salah, Patel, Parth, Kirby, James Edward, Rowley, Christopher Francis, Berg, Katherine Margaret, Moskowitz, Ari, Donnino, Michael William

“…The relationship between COVID-19 severity and viral load is unknown. Our objective was to assess the association between viral load and disease severity in…”
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Cellular oxygen consumption in patients with diabetic ketoacidosis by Vine, Jacob, Lee, John H., Balaji, Lakshman, Grossestreuer, Anne V., Morton, Andrea, Peradze, Natia, Antony, Nivedha, Berlin, Noa, Kravitz, Max S., Leland, Shannon B., Berg, Katherine, Moskowitz, Ari, Donnino, Michael W., Liu, Xiaowen

“…Background Diabetic ketoacidosis (DKA) is a potentially life-threatening disorder associated with severe alterations in metabolism and acid–base status…”
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The Selective Peroxisome Proliferator‐Activated Receptor Gamma Modulator CHS‐131 Improves Liver Histopathology and Metabolism in a Mouse Model of Obesity and Nonalcoholic Steatohepatitis by Perakakis, Nikolaos, Joshi, Aditya, Peradze, Natia, Stefanakis, Konstantinos, Li, Georgia, Feigh, Michael, Veidal, Sanne Skovgard, Rosen, Glenn, Fleming, Michael, Mantzoros, Christos S.

“…CHS‐131 is a selective peroxisome proliferator‐activated receptor gamma modulator with antidiabetic effects and less fluid retention and weight gain compared…”
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Circulating levels of gastrointestinal hormones in response to the most common types of bariatric surgery and predictive value for weight loss over one year: Evidence from two independent trials by Perakakis, Nikolaos, Kokkinos, Alexander, Peradze, Natia, Tentolouris, Nikolaos, Ghaly, Wael, Pilitsi, Eleni, Upadhyay, Jagriti, Alexandrou, Andreas, Mantzoros, Christos S.

“…Bariatric surgery leads to profound and sustainable weight loss. Gastrointestinal hormones are involved in energy and glucose homeostasis, thus postoperative…”
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Physiology of Activins/Follistatins: Associations With Metabolic and Anthropometric Variables and Response to Exercise by Perakakis, Nikolaos, Mougios, Vassilis, Fatouros, Ioannis, Siopi, Aikaterina, Draganidis, Dimitrios, Peradze, Natia, Ghaly, Wael, Mantzoros, Christos S

“…Clinical trials are evaluating the efficacy of inhibitors of the myostatin pathway in neuromuscular and metabolic diseases. Activins and follistatins are major…”
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983: CELLULAR OXYGEN CONSUMPTION IN PATIENTS WITH DIABETIC KETOACIDOSIS by Vine, Jacob, Lee, john, Balaji, Lakshman, Grossestreuer, Anne, Morton, Andrea, Peradze, Natia, Berg, Katherine, Moskowitz, Ari, Donnino, Michael, Liu, Xiaowen

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Follistatins in glucose regulation in healthy and obese individuals by Perakakis, Nikolaos, Kokkinos, Alexander, Peradze, Natia, Tentolouris, Nicholas, Ghaly, Wael, Tsilingiris, Dimitrios, Alexandrou, Andreas, Mantzoros, Christos S.

“…Aims It has been suggested recently that follistatin (FST) and its homologous protein, follistatin‐like 3 (FSTL3), may be a therapeutic target in the treatment…”
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The role of plant-based dietary patterns in reducing COVID-19 risk and/or severity in adults: A systematic review and meta-analysis of observational studies by Papadaki, Angeliki, Coy, Eimear Mc, Anastasilakis, Dimitrios A., Peradze, Natia, Mantzoros, Christos S.

“…Plant-based dietary patterns (PBDs) might protect against COVID-19 risk and reduce severity of infection. This systematic review with meta-analysis aimed to…”
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Circulating levels of the components of the GH/IGF-1/IGFBPs axis total and intact IGF-binding proteins (IGFBP) 3 and IGFBP 4 and total IGFBP 5, as well as PAPPA, PAPPA2 and Stanniocalcin-2 levels are not altered in response to energy deprivation and/or metreleptin administration in humans by Pilitsi, Eleni, Peradze, Natia, Perakakis, Nikolaos, Mantzoros, Christos S.

“…It remains unclear whether food deprivation induces changes in components of the GH/IGF-1/IGFBPs axis and if yes, which ones are mediated by leptin, an…”
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Metabolic regulation of activins in healthy individuals and in obese patients undergoing bariatric surgery by Perakakis, Nikolaos, Kokkinos, Alexander, Peradze, Natia, Tentolouris, Nikolaos, Ghaly, Wael, Tsilingiris, Dimitrios, Alexandrou, Andreas, Mantzoros, Christos S.

“…Objective Follistatin binds and inactivates activins, which are potent inhibitors of muscle growth and metabolism and are currently being developed for the…”
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Research developments in metabolism 2018 by Peradze, Natia, Farr, Olivia M., Mantzoros, Christos S.

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Thiamine as a metabolic resuscitator after in-hospital cardiac arrest by Berg, Katherine M., Grossestreuer, Anne V., Balaji, Lakshman, Moskowitz, Ari, Berlin, Noa, Cocchi, Michael N., Morton, Andrea C., Li, Franklin, Mehta, Shivani, Peradze, Natia, Silverman, Jeremy, Liu, Xiaowen, Donnino, Michael W.

“…Elevated lactate is associated with mortality after cardiac arrest. Thiamine, a cofactor of pyruvate dehydrogenase, is necessary for aerobic metabolism. In a…”
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Mesenchymal stem cell (MSC)-mediated survival of insulin producing pancreatic β-cells during cellular stress involves signalling via Akt and ERK1/2 by Liu, Chune, Zhang, Weiwei, Peradze, Natia, Lang, Leonie, Straetener, Jan, Feilen, Peter J., Alt, Marcus, Jäger, Christina, Laubner, Katharina, Perakakis, Nikolaos, Seufert, Jochen, Päth, Günter

“…Mesenchymal stem cells (MSC) are of interest for cell therapy since their secreted factors mediate immunomodulation and support tissue regeneration. This study…”
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Follistatins in glucose regulation of healthy and obese subjects by Perakakis, Nikolaos, Kokkinos, Alexander, Peradze, Natia, Tentolouris, Nicholas, Ghaly, Wael, Tsilingiris, Dimitrios, Alexandrou, Andreas, Mantzoros, Christos S.

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Research advances in metabolism 2017 by Perakakis, Nikolaos, Ghaly, Wael, Peradze, Natia, Boutari, Chrysoula, Batirel, Saime, Douglas, Vivian Paraskevi, Mantzoros, Christos S.

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Diabetic Ketoacidosis and Dysregulation of Proglucagon Family of Molecules by Peradze, Natia, Heydrick, Stanley, Cole, Andrew, Moskowitz, Ari, Donnino, Michael, Liu, Xiaowen

“…An increasing body of evidence supports a significant contributory role for pancreatic α-cell dysfunction in the pathophysiology of diabetic ketoacidosis…”
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OR01-5 Leptin Acts through Altering Energy Intake and Lipolysis to Reduce Body Weight but Has No Effect on Energy Expenditure, Physical Activity, and Sympathetic Nervous System in Humans by Chrysafi, Pavlina, Peradze, Natia, Stefanakis, Konstantinos, Pilitsi, Eleni, Farr, Olivia, Mantzoros, Christos

“…It remains unknown whether leptin regulates body weight in humans and whether this occurs through actions centrally and/or peripherally i.e. by altering…”
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