Incidence of chronic myeloid leukemia in 6 regions of Russia according to the data of the 2009-2012 population-based study

To assess the main epidemiological characteristics of chronic myeloid leukemia (CML) in the Russian Federation. A planned epidemiological prospective study was conducted in 2009-2012 in 6 Russian regions with the total number of 10.1 million inhabitants, which notified all new CML cases. The unstand...

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Bibliographic Details
Published in:	Terapevtic̆eskii arhiv Vol. 86; no. 7; pp. 24 - 30
Main Authors:	Kulikov, S M, Vinogradova, O Iu, Chelysheva, E Iu, Tishchenko, I A, Galaĭko, M A, Lazareva, O V, Senderova, O M, Pepeliaeva, V M, Meresiĭ, S V, Luchinin, A S, Ovsepian, V A, Miliutina, G I, Gavrilova, L V, Avdeeva, L B, Neverova, A L, Turkina, A G
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) "Consilium Medicum" Publishing house 01-01-2014
Subjects:	Adult Age Factors Aged chronic myeloid leukemia Humans Incidence Leukemia, Myelogenous, Chronic, BCR-ABL Positive - diagnosis Leukemia, Myelogenous, Chronic, BCR-ABL Positive - epidemiology Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy Middle Aged morbidity population-based study Registries Russia - epidemiology Russia
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Summary:	To assess the main epidemiological characteristics of chronic myeloid leukemia (CML) in the Russian Federation. A planned epidemiological prospective study was conducted in 2009-2012 in 6 Russian regions with the total number of 10.1 million inhabitants, which notified all new CML cases. The unstandardized (unnormalized, baseline) recorded incidence of CML in the examined regions was 0.58 per 100,000 annually. Its standardized (normalized) incidence was 0.70 for the WHO standard population and 0.72 for the European standard population. The regional variations in the incidence were 0.44 to 0.69. The structural analysis of the incidence in the age strata indicated that the overall morbidity was less due to the decreased rate of registration in old age groups. The morbidity rates in patients aged less than 60 years were nearly similar to the European rates; those in patients aged over 70 years were almost 10 times lower. The lower rate of detection and screening diagnosis of CML in pensioners in primary health care is discussed. The data obtained in this study may serve as the starting point for monitoring the CML epidemiological situation.
ISSN:	0040-3660 2309-5342