Search Results - "Peoples, Jessica N."

Mitochondrial dysfunction and oxidative stress in heart disease by Peoples, Jessica N., Saraf, Anita, Ghazal, Nasab, Pham, Tyler T., Kwong, Jennifer Q.

“…Beyond their role as a cellular powerhouse, mitochondria are emerging as integral players in molecular signaling and cell fate determination through reactive…”
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The mitochondrial citrate carrier SLC25A1 regulates metabolic reprogramming and morphogenesis in the developing heart by Ohanele, Chiemela, Peoples, Jessica N., Karlstaedt, Anja, Geiger, Joshua T., Gayle, Ashley D., Ghazal, Nasab, Sohani, Fateemaa, Brown, Milton E., Davis, Michael E., Porter, George A., Faundez, Victor, Kwong, Jennifer Q.

“…The developing mammalian heart undergoes an important metabolic shift from glycolysis towards mitochondrial oxidation that is critical to support the…”
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Impaired cardiac energy metabolism in embryos lacking adrenergic stimulation by Baker, Candice N, Gidus, Sarah A, Price, George F, Peoples, Jessica N R, Ebert, Steven N

“…As development proceeds from the embryonic to fetal stages, cardiac energy demands increase substantially, and oxidative phosphorylation of ADP to ATP in…”
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Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome by Peoples, Jessica N, Ghazal, Nasab, Duong, Duc M, Hardin, Katherine R, Manning, Janet R, Seyfried, Nicholas T, Faundez, Victor, Kwong, Jennifer Q

“…Mitochondria are recognized as signaling organelles, because under stress, mitochondria can trigger various signaling pathways to coordinate the cell's…”
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Intact calcium signaling in adrenergic-deficient embryonic mouse hearts by Peoples, Jessica N., Taylor, David G., Katchman, Alexander N., Ebert, Steven N.

“…Mouse embryos that lack the ability to produce the adrenergic hormones, norepinephrine (NE) and epinephrine (EPI), due to disruption of the dopamine…”
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Metabolomics reveals critical adrenergic regulatory checkpoints in glycolysis and pentose–phosphate pathways in embryonic heart by Peoples, Jessica N.R., Maxmillian, Timmi, Le, Quynh, Nadtochiy, Sergiy M., Brookes, Paul S., Porter, George A., Davidson, Victor L., Ebert, Steven N.

“…Cardiac energy demands during early embryonic periods are sufficiently met through glycolysis, but as development proceeds, the oxidative phosphorylation in…”
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Abstract P3048: Establishing The Mitochondrial Citrate Transporter As A Regulator Of Cardiac Development by Ghazal, Nasab, Peoples, Jessica N, Rodgers, Allie A, Park, Austin S, Kwong, Jennifer Q

“…IntroductionMitochondria are essential to provide oxidative energy to fuel excitation-contraction coupling of the postnatal heart. The role of mitochondrial…”
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Abstract 345: Dramatic ATP Depletion Without Concomitant Declines in ATP Synthesis Rates Suggests Impaired Energy Metabolism Mechanisms in Adrenergic-Deficient Mouse Embryos by Peoples, Jessica N, Baker, Candice, Ebert, Steven

“…Abstract only High cardiac energy demands increase during embryonic development, requiring oxidative phosphorylation converting ADP to ATP in mitochondria to…”
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