Search Results - "Penumathsa, Suresh Varma"

Akt/FOXO3a/SIRT1-Mediated Cardioprotection by n-Tyrosol against Ischemic Stress in Rat in Vivo Model of Myocardial Infarction: Switching Gears toward Survival and Longevity by Samuel, Samson Mathews, Thirunavukkarasu, Mahesh, Penumathsa, Suresh Varma, Paul, Debayon, Maulik, Nilanjana

“…Moderate consumption of wine has been associated with decreased risk of cardiovascular events. Recently we have shown that white wine is equally as…”
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Thioredoxin-1 Gene Therapy Enhances Angiogenic Signaling and Reduces Ventricular Remodeling in Infarcted Myocardium of Diabetic Rats by SAMUEL, Samson Mathews, THIRUNAVUKKARASU, Mahesh, VARMA PENUMATHSA, Suresh, KONERU, Srikanth, LIJUN ZHAN, MAULIK, Gautam, SUDHAKARAN, Perumana R, MAULIK, Nilanjana

“…The present study evaluated the reversal of diabetes-mediated impairment of angiogenesis in a myocardial infarction model of type 1 diabetic rats by…”
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Sildenafil‐mediated neovascularization and protection against myocardial ischaemia reperfusion injury in rats: role of VEGF/angiopoietin‐1 by Koneru, Srikanth, Varma Penumathsa, Suresh, Thirunavukkarasu, Mahesh, Vidavalur, Ramesh, Zhan, Lijun, Singal, Pawan K., Engelman, Richard M, Das, Dipak K, Maulik, Nilanjana

“…Sildenafil citrate (SC), a drug for erectile dysfunction, is now emerging as a cardiopulmonary drug. Our study aimed to determine a novel role of sildenafil on…”
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Resveratrol: a promising agent in promoting cardioprotection against coronary heart disease by Penumathsa, Suresh Varma, Maulik, Nilanjana

“…The inverse association between alcohol intake and coronary heart disease has been consistently reported in cross-culture, case-control, and cohort studies…”
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Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase by Thirunavukkarasu, Mahesh, Penumathsa, Suresh Varma, Koneru, Srikanth, Juhasz, Bela, Zhan, Lijun, Otani, Hajime, Bagchi, Debasis, Das, Dipak K., Maulik, Nilanjana

“…Excessive oxidative stress has been implicated in the pathology and complications of diabetes, which leads to myocardial ischemia reperfusion injury. The…”
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Hepatoprotective role of ferulic acid: a dose-dependent study by Rukkumani, Rajagopalan, Aruna, Kode, Suresh Varma, Penumathsa, Padmanabhan Menon, Venugopal

“…Alcohol use is contributing to an unprecedented decline in life expectancy. Damage to the liver after ethanol administration is a well-known phenomenon. Free…”
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Effective proactive routing protocol using smart nodes system by Venkatanaresh, M., Yadav, Ranjeet, Thiyagarajan, D., Yasotha, S., Ramkumar, Gowtham, Varma, Penumathsa Suresh

“…Small Power Restricted Unit (PRU) platform known as the Wireless Sensor Network (WSN) to monitor a Large Region of Interest (ROI) and send data to the Base…”
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Statin and resveratrol in combination induces cardioprotection against myocardial infarction in hypercholesterolemic rat by Penumathsa, Suresh Varma, Thirunavukkarasu, Mahesh, Koneru, Srikanth, Juhasz, Bela, Zhan, Lijun, Pant, Rima, Menon, Venugopal P, Otani, Hajime, Maulik, Nilanjana

“…Abstract Hypercholesterolemia (HC) is a common health problem that significantly increases risk of cardiovascular disease. Both statin ( S ) and resveratrol (…”
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Strategic targets to induce neovascularization by resveratrol in hypercholesterolemic rat myocardium: Role of caveolin-1, endothelial nitric oxide synthase, hemeoxygenase-1, and vascular endothelial growth factor by Penumathsa, Suresh Varma, Koneru, Srikanth, Samuel, Samson Mathews, Maulik, Gautam, Bagchi, Debasis, Yet, Shaw-Fang, Menon, Venogopal P., Maulik, Nilanjana

“…Endothelial dysfunction and impaired angiogenesis constitute a hallmark of hypercholesterolemia. This study was designed to examine the effects of resveratrol,…”
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Secoisolariciresinol diglucoside: relevance to angiogenesis and cardioprotection against ischemia-reperfusion injury by Penumathsa, Suresh Varma, Koneru, Srikanth, Thirunavukkarasu, Mahesh, Zhan, Lijun, Prasad, Kailash, Maulik, Nilanjana

“…Therapeutic angiogenesis represents a novel approach for the prevention and treatment of ischemic heart disease. This study examined a novel method of…”
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Bromelain induces cardioprotection against ischemia-reperfusion injury through Akt/FOXO pathway in rat myocardium by Juhasz, Bela, Thirunavukkarasu, Mahesh, Pant, Rima, Zhan, Lijun, Penumathsa, Suresh Varma, Secor, Jr, Eric R, Srivastava, Sapna, Raychaudhuri, Utpal, Menon, Venugopal P, Otani, Hajime, Thrall, Roger S, Maulik, Nilanjana

“…Bromelain (Br), a proteolytic enzyme extracted from the stem of the pineapple, is known to possess anti-inflammatory activity and has been shown to reduce…”
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Redox regulation of ischemic preconditioning is mediated by the differential activation of caveolins and their association with eNOS and GLUT-4 by Koneru, Srikanth, Penumathsa, Suresh Varma, Thirunavukkarasu, Mahesh, Samuel, Samson Mathews, Zhan, Lijun, Han, Zhihua, Maulik, Gautam, Das, Dipak K, Maulik, Nilanjana

“…Reactive oxygen species (ROS) generated during ischemia-reperfusion (I/R) enhance myocardial injury, but brief periods of myocardial ischemia followed by…”
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Sildenafil induces angiogenic response in human coronary arteriolar endothelial cells through the expression of thioredoxin, hemeoxygenase and vascular endothelial growth factor by Vidavalur, Ramesh, Penumathsa, Suresh Varma, Zhan, Lijun, Thirunavukkarasu, Mahesh, Maulik, Nilanjana

“…This study was undertaken to investigate the effect of phosphodiesterase-5 (PDE5) inhibitor, sildenafil, on angiogenic response in human coronary arteriolar…”
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White Wine Induced Cardioprotection against Ischemia-Reperfusion Injury Is Mediated by Life Extending Akt/FOXO3a/NFκB Survival Pathway by Thirunavukkarasu, Mahesh, Penumathsa, Suresh Varma, Samuel, Samson Mathews, Akita, Yuzo, Zhan, Lijun, Bertelli, Alberto A. E., Maulik, Gautam, Maulik, Nilanjana

“…Recent studies on the protection afforded by moderate wine consumption against cardiovascular diseases have focused mainly on the activity of red wine in view…”
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Comparative Effects of Curcumin and an Analogue of Curcumin in Carbon Tetrachloride‐Induced Hepatotoxicity in Rats by Kamalakkannan, Narasimhanaidu, Rukkumani, Rajagopalan, Varma, Penumathsa Suresh, Viswanathan, Periyasamy, Rajasekharan, Kallikat Narayanan, Menon, Venugopal Padmanabhan

“…: We have evaluated the comparative effect of curcumin (diferuloyl methane) and its analogue [bis‐1,7‐(2‐hydroxyphenyl)‐hepta‐1,6‐diene‐3,5‐dione] (BDMC‐A) on…”
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Influence of a thiazole derivative on ethanol and thermally oxidized sunflower oil-induced oxidative stress by Kode, Aruna, Rajagopalan, Rukkumani, Penumathsa, Suresh Varma, Menon, Venugopal P.

“…The present work describes the protective influence of the dendrodoine analogue (DA) [4‐amino‐5‐benzoyl‐2‐(4‐methoxy phenylamino) thiazole] on thermally…”
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Effect of ethanol and thermally oxidized sunflower oil ingestion on phospholipid fatty acid composition of rat liver: protective role of Cuminum cyminum L by Kode, Aruna, Rajagopalan, Rukkumani, Penumathsa, Suresh Varma, Menon, Venugopal P

“…The current study was undertaken to assess the effect of ethanol and thermally oxidized sunflower oil ingestion on liver phospholipid fatty acids and the…”
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Niacin bound chromium treatment induces myocardial Glut-4 translocation and caveolar interaction via Akt, AMPK and eNOS phosphorylation in streptozotocin induced diabetic rats after ischemia-reperfusion injury by Penumathsa, Suresh Varma, Thirunavukkarasu, Mahesh, Samuel, Samson Mathews, Zhan, Lijun, Maulik, Gautam, Bagchi, Manashi, Bagchi, Debasis, Maulik, Nilanjana

“…Diabetes, one of the major risk factors of metabolic syndrome culminates in the development of Ischemic Heart Disease (IHD). Refined diets that lack…”
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Secoisolariciresinol diglucoside induces neovascularization-mediated cardioprotection against ischemia–reperfusion injury in hypercholesterolemic myocardium by Penumathsa, Suresh Varma, Koneru, Srikanth, Zhan, Lijun, John, Saji, Menon, Venogopal P, Prasad, Kailash, Maulik, Nilanjana

“…Abstract Hypercholesterolemia (HC) induced endothelial cell dysfunction and decreased endothelial nitric oxide formation results in impaired angiogenesis and…”
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Adeno-sh-beta-catenin abolishes ischemic preconditioning-mediated cardioprotection by downregulation of its target genes VEGF, Bcl-2, and survivin in ischemic rat myocardium by Thirunavukkarasu, Mahesh, Han, Zhihua, Zhan, Lijun, Penumathsa, Suresh Varma, Menon, Venugopal P, Maulik, Nilanjana

“…beta-Catenin, the downstream target of glycogen synthase kinase-3beta (GSK-3beta), plays a vital role in ischemic preconditioning (IP)-mediated…”
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