Search Results - "Pentz, Ellen S"
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The MicroRNA-Processing Enzyme Dicer Maintains Juxtaglomerular Cells
Published in Journal of the American Society of Nephrology (01-03-2010)“…Juxtaglomerular cells are highly specialized myoepithelioid granulated cells located in the glomerular afferent arterioles. These cells synthesize and release…”
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Aldo-keto reductase 1b7, a novel marker for renin cells, is regulated by cyclic AMP signaling
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-09-2015)“…We previously identified aldo-keto reductase 1b7 (AKR1B7) as a marker for juxtaglomerular renin cells in the adult mouse kidney. However, the distribution of…”
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3
Fate and plasticity of renin precursors in development and disease
Published in Pediatric nephrology (Berlin, West) (01-04-2014)“…Renin-expressing cells appear early in the embryo and are distributed broadly throughout the body as organogenesis ensues. Their appearance in the metanephric…”
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Transcriptional regulator RBP-J regulates the number and plasticity of renin cells
Published in Physiological genomics (01-09-2011)“…Renin-expressing cells are crucial in the control of blood pressure and fluid-electrolyte homeostasis. Notch receptors convey cell-cell signals that may…”
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Embryonic origin and lineage of juxtaglomerular cells
Published in American journal of physiology. Renal physiology (01-08-2001)“…To define the embryonic origin and lineage of the juxtaglomerular (JG) cell, transplantation of embryonic kidneys between genetically marked and wild-type…”
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Genes that Confer the Identity of the Renin Cell
Published in Journal of the American Society of Nephrology (01-12-2011)“…Renin-expressing cells modulate BP, fluid-electrolyte homeostasis, and kidney development, but remarkably little is known regarding the genetic regulatory…”
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Recombination signal binding protein for Ig-κJ region regulates juxtaglomerular cell phenotype by activating the myo-endocrine program and suppressing ectopic gene expression
Published in Journal of the American Society of Nephrology (01-01-2015)“…Recombination signal binding protein for Ig-κJ region (RBP-J), the major downstream effector of Notch signaling, is necessary to maintain the number of…”
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Renin Cells Are Precursors for Multiple Cell Types that Switch to the Renin Phenotype When Homeostasis Is Threatened
Published in Developmental cell (01-05-2004)“…Renin-synthesizing cells are crucial in the regulation of blood pressure and fluid-electrolyte homeostasis. Adult mammals subjected to manipulations that…”
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Identification of renin progenitors in the mouse bone marrow that give rise to B-cell leukaemia
Published in Nature communications (18-02-2014)“…The cell of origin and triggering events for leukaemia are mostly unknown. Here we show that the bone marrow contains a progenitor that expresses renin…”
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Two microRNAs, miR-330 and miR-125b-5p, mark the juxtaglomerular cell and balance its smooth muscle phenotype
Published in American journal of physiology. Renal physiology (01-01-2012)“…We have shown that microRNAs (miRNAs) are necessary for renin cell specification and kidney vascular development. Here, we used a screening strategy involving…”
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Abstract 300: The Notch Signaling Pathway Regulates the Fate of Renal FOXD1+ Stromal Cells and Their Descendants
Published in Hypertension (Dallas, Tex. 1979) (01-09-2014)“…Abstract only The mechanisms underlying the establishment, assembly and maintenance of the renal blood vessels are poorly understood. We have previously shown…”
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Abstract 066: Enhancer Repertoires That Define Renin Cell Identity
Published in Hypertension (Dallas, Tex. 1979) (01-09-2016)“…Abstract only Control of the renin cell phenotype is crucial for the regulation of blood pressure and fluid- electrolyte homeostasis. Enhancers are cis -acting…”
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Abstract 38: Rbp-j Regulates the Genetic Program of the Myo-epithelioid JG Cell
Published in Hypertension (Dallas, Tex. 1979) (01-09-2012)“…Abstract only RBP-J , the major downstream effector of Notch signaling, is necessary to maintain the number of juxtaglomerular (JG) cells. In addition, RBP-J…”
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Renin-expressing cells are associated with branching of the developing kidney vasculature
Published in Journal of the American Society of Nephrology (1998)“…To define the relationship between renal vascular development and renin distribution during kidney ontogeny, the complete renal arterial tree of Sprague Dawley…”
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Biomechanical coupling in renin-releasing cells
Published in The Journal of clinical investigation (15-09-1997)“…The renin-angiotensin system is a major regulatory system controlling extracellular fluid volume and blood pressure. The rate-limiting enzyme in this hormonal…”
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Ren1d and Ren2 cooperate to preserve homeostasis: evidence from mice expressing GFP in place of Ren1d
Published in Physiological genomics (06-06-2001)“…1 Department of Pediatrics, University of Virginia, Charlottesville, Virginia 22908 2 Department of Pathology and Laboratory Medicine, University of North…”
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Ren1 d and Ren2 cooperate to preserve homeostasis: evidence from mice expressing GFP in place of Ren1 d
Published in Physiological genomics (06-06-2001)“…To distinguish the contributions of Ren1 d and Ren2 to kidney development and blood pressure homeostasis, we placed green fluorescent protein (GFP) under…”
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genetic and molecular organization of the Dopa decarboxylase gene cluster of Drosophila melanogaster
Published in Genetics (Austin) (01-10-1995)“…We report the complete molecular organization of the Dopa decarboxylase gene cluster. Mutagenesis screens recovered 77 new Df(2L)TW130 recessive lethal…”
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Molecular cloning of KS, a novel rat gene expressed exclusively in the kidney
Published in Kidney international (01-11-1998)“…Molecular cloning of xKSx, a novel rat gene expressed exclusively in the kidney. We aimed to identify genes with kidney specific, developmentally regulated…”
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Angiotensin-dependent gene expression in the developing rat kidney
Published in Kidney international (01-09-1998)“…Angiotensin-dependent gene expression in the developing rat kidney. We aimed to identify genes involved in the growth effects of angiotensin II (Ang II) during…”
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