Search Results - "Pentecost, Brian T."

Three-dimensional architecture of epithelial primary cilia by Sun, Shufeng, Fisher, Rebecca L., Bowser, Samuel S., Pentecost, Brian T., Sui, Haixin

“…We report a complete 3D structural model of typical epithelial primary cilia based on structural maps of full-length primary cilia obtained by serial section…”
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Durable antibody and effector memory T cell responses in breastmilk from women with SARS-CoV-2 by Narayanaswamy, Vignesh, Pentecost, Brian T, Telfer, Janice C, Burnside, Amy S, Schneider, Sallie S, Alfandari, Dominique, Baker, Ryan L, Saiju, Aman, Nodiff, Sam, Arcaro, Kathleen F

“…Given that only 25% of pregnant women elect to receive a COVID-19 vaccine, maternal SARS-CoV-2 infection remains an important route of conferring protective…”
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Mass Spectrometry-Based Proteomics of Human Milk to Identify Differentially Expressed Proteins in Women with Breast Cancer versus Controls by Aslebagh, Roshanak, Whitham, Danielle, Channaveerappa, Devika, Mutsengi, Panashe, Pentecost, Brian T, Arcaro, Kathleen F, Darie, Costel C

“…It is thought that accurate risk assessment and early diagnosis of breast cancer (BC) can help reduce cancer-related mortality. Proteomics analysis of breast…”
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Mammary epithelium permeability during established lactation: associations with cytokine levels in human milk by Kivlighan, Katie T, Schneider, Sallie S, Browne, Eva P, Pentecost, Brian T, Anderton, Douglas L, Arcaro, Kathleen F

“…The cytokine profile of human milk may be a key indicator of mammary gland health and has been linked to infant nutrition, growth, and immune system…”
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High-density array analysis of DNA methylation in Tamoxifen-resistant breast cancer cell lines by Williams, Kristin E, Anderton, Douglas L, Lee, Maxwell P, Pentecost, Brian T, Arcaro, Kathleen F

“…Roughly two-thirds of all breast cancers are ERα-positive and can be treated with the antiestrogen, Tamoxifen, however resistance occurs in 33% of women who…”
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Neutralizing Antibodies and Cytokines in Breast Milk After Coronavirus Disease 2019 (COVID-19) mRNA Vaccination by Narayanaswamy, Vignesh, Pentecost, Brian T, Schoen, Corina N, Alfandari, Dominique, Schneider, Sallie S, Baker, Ryan, Arcaro, Kathleen F

“…To evaluate immune responses to coronavirus disease 2019 (COVID-19) mRNA-based vaccines present in breast milk and transfer of the immune responses to…”
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Use of an Aggressive MCF-7 Cell Line Variant, TMX2-28, to Study Cell Invasion in Breast Cancer by Gozgit, Joseph M, Pentecost, Brian T, Marconi, Sharon A, Otis, Christopher N, Wu, Chuanyue, Arcaro, Kathleen F

“…An estrogen receptor–negative variant of the MCF-7 breast cancer cell line, TMX2-28, was used as a model in which to study breast cancer cell invasion. Using a…”
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Proteomics analysis of human breast milk by two‐dimensional polyacrylamide gel electrophoresis (2D‐PAGE) coupled with mass spectrometry to assess breast cancer risk by Aslebagh, Roshanak, Whitham, Danielle, Channaveerappa, Devika, Lowe, James, Pentecost, Brian T., Arcaro, Kathleen F., Darie, Costel C.

“…Breast cancer (BC) is one of the most common cancers and one of the most common causes for cancer‐related mortality. Discovery of protein biomarkers associated…”
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Differential action of polycyclic aromatic hydrocarbons on endogenous estrogen-responsive genes and on a transfected estrogen-responsive reporter in MCF-7 cells by Gozgit, Joseph M, Nestor, Kathleen M, Fasco, Michael J, Pentecost, Brian T, Arcaro, Kathleen F

“…Polycyclic aromatic hydrocarbons (PAHs) are common environmental pollutants that have been extensively studied for multiple toxicological endpoints in both…”
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The Developmental Process of the Growing Motile Ciliary Tip Region by Reynolds, Matthew J., Phetruen, Tanaporn, Fisher, Rebecca L., Chen, Ke, Pentecost, Brian T., Gomez, George, Ounjai, Puey, Sui, Haixin

“…Eukaryotic motile cilia/flagella play vital roles in various physiological processes in mammals and some protists. Defects in cilia formation underlie multiple…”
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DNA methylation in breast cancers: Differences based on estrogen receptor status and recurrence by Williams, Kristin E., Jawale, Rahul M., Schneider, Sallie S., Otis, Christopher N., Pentecost, Brian T., Arcaro, Kathleen F.

“…DNA methylation plays a role in the etiology of primary breast cancers. We analyzed paired primary and second breast tumors to elucidate the role of…”
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Investigations of the posttranslational mechanism of arsenite-mediated downregulation of human cytochrome P4501A1 levels: The role of heme oxygenase-1 by Bessette, Erin E., Fasco, Michael J., Pentecost, Brian T., Reilly, Andrew, Kaminsky, Laurence S.

“…Arsenite, an environmental cocontaminant of polycyclic aromatic hydrocarbons (PAHs), diminishes the PAH‐mediated upregulation of human CYP1A1, the enzyme that…”
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MECHANISMS OF ARSENITE-MEDIATED DECREASES IN BENZO[K]FLUORANTHENE-INDUCED HUMAN CYTOCHROME P4501A1 LEVELS IN HEPG2 CELLS by BESSETTE, Erin E, FASCO, Michael J, PENTECOST, Brian T, KAMINSKY, Laurence S

“…Polycyclic aromatic hydrocarbons (PAHs) and heavy metals are often environmental cocontaminants that could interact to alter PAH carcinogenicity. The heavy…”
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The RhoA pathway mediates MMP-2 and MMP-9-independent invasive behavior in a triple-negative breast cancer cell line by Fagan-Solis, Katerina D., Schneider, Sallie Smith, Pentecost, Brian T., Bentley, Brook A., Otis, Christopher N., Gierthy, John F., Arcaro, Kathleen F.

“…Breast cancer is a heterogeneous disease that varies in its biology and response to therapy. A foremost threat to patients is tumor invasion and metastasis,…”
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SKP2 Overexpression Is Associated With Increased Serine 10 Phosphorylation of p27 (pSer10p27) in Triple-Negative Breast Cancer by Fagan-Solis, Katerina D., Pentecost, Brian T., Gozgit, Joseph M., Bentley, Brooke A., Marconi, Sharon M., Otis, Christopher N., Anderton, Douglas L., Schneider, Sallie Smith, Arcaro, Kathleen F.

“…S‐phase kinase‐associated protein 2 (SKP2) is an important cell cycle regulator, targeting the cyclin‐dependent kinase (CDK) inhibitor p27 for degradation, and…”
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Induction of CYP1A1 and CYP1B1 by benzo( k)fluoranthene and benzo( a)pyrene in T-47D human breast cancer cells: Roles of PAH interactions and PAH metabolites by Spink, David C., Wu, Susan J., Spink, Barbara C., Hussain, Mirza M., Vakharia, Dilip D., Pentecost, Brian T., Kaminsky, Laurence S.

“…The interactions of polycyclic aromatic hydrocarbons (PAH) and cytochromes P450 (CYP) are complex; PAHs are enzyme inducers, substrates, and inhibitors. In…”
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Role of the insulin-like growth factor system on an estrogen-dependent cancer phenotype in the MCF-7 human breast cancer cell line by Bradley, Laurie M., Gierthy, John F., Pentecost, Brian T.

“…We previously established that exposure of the estrogen receptor (ER) α positive MCF-7 human breast cancer cell line to 17-β-estradiol (E 2) results in the…”
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ELF5 and DOK7 regulation in anti-estrogen treated cells and tumors by Fitzgerald, Lily M, Browne, Eva P, Christie, Kevin D, Punska, Elizabeth C, Simmons, Leo O, Williams, Kristin E, Pentecost, Brian T, M Jawale, Rahul, Otis, Christopher N, Arcaro, Kathleen F

“…Most women with primary breast cancers that express estrogen receptor alpha (ER or ESR1) are treated with endocrine therapies including the anti-estrogen…”
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Long-term estrogen exposure promotes carcinogen bioactivation, induces persistent changes in gene expression, and enhances the tumorigenicity of MCF-7 human breast cancer cells by Spink, Barbara C., Bennett, James A., Pentecost, Brian T., Lostritto, Nicole, Englert, Neal A., Benn, Geoffrey K., Goodenough, Angela K., Turesky, Robert J., Spink, David C.

“…The cumulative exposure to estrogens is an important determinant in the risk of breast cancer, yet the full range of mechanisms involving estrogens in the…”
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Estrogen regulates Ah responsiveness in MCF-7 breast cancer cells by Spink, David C., Katz, Barbara H., Hussain, Mirza M., Pentecost, Brian T., Cao, Zhimin, Spink, Barbara C.

“…Cytochrome P450 (CYP)1A1 and CYP1B1, which are under the regulatory control of the aryl hydrocarbon (Ah) receptor (AhR), catalyze the metabolic activation of…”
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