Search Results - "Penno, Megan A."

Dietary patterns during pregnancy and maternal and birth outcomes in women with type 1 diabetes: the Environmental Determinants of Islet Autoimmunity (ENDIA) study by Thomson, Rebecca L., Brown, James D., Oakey, Helena, Palmer, Kirsten, Ashwood, Pat, Penno, Megan A. S., McGorm, Kelly J., Battersby, Rachel, Colman, Peter G., Craig, Maria E., Davis, Elizabeth A., Huynh, Tony, Harrison, Leonard C., Haynes, Aveni, Sinnott, Richard O., Vuillermin, Peter J., Wentworth, John M., Soldatos, Georgia, Couper, Jennifer J.

“…Aims/hypothesis Dietary patterns characterised by high intakes of vegetables may lower the risk of pre-eclampsia and premature birth in the general population…”
Get full text

Identification and validation of novel candidate protein biomarkers for the detection of human gastric cancer by Humphries, Julia M., Penno, Megan A.S., Weiland, Florian, Klingler-Hoffmann, Manuela, Zuber, Agnieszka, Boussioutas, Alex, Ernst, Matthias, Hoffmann, Peter

“…The timely detection of gastric cancer will contribute significantly towards effective treatment and is aided by the availability and reliability of…”
Get full text

Evaluation of protocol amendments to the Environmental Determinants of Islet Autoimmunity (ENDIA) study during the COVID‐19 pandemic by Penno, Megan A. S., Anderson, Amanda J., Thomson, Rebecca L., McGorm, Kelly, Barry, Simon C., Colman, Peter G., Craig, Maria E., Davis, Elizabeth A., Harris, Mark, Haynes, Aveni, Morahan, Grant, Oakey, Helena, Rawlinson, William D., Sinnott, Richard O., Soldatos, Georgia, Vuillermin, Peter J., Wentworth, John M., Harrison, Leonard C., Couper, Jennifer J.

Get full text

Potential mechanisms of the acute coronary syndrome presentation in patients with the coronary slow flow phenomenon — Insight from a plasma proteomic approach by Kopetz, Victoria A, Penno, Megan A.S, Hoffmann, Peter, Wilson, David P, Beltrame, John F

“…Abstract Aims The coronary slow flow phenomenon [CSFP] is a coronary microvascular disorder, characterized by delayed distal vessel opacification despite the…”
Get full text

Optimization of Blood Handling and Peripheral Blood Mononuclear Cell Cryopreservation of Low Cell Number Samples by Hope, Christopher M., Huynh, Dao, Wong, Ying Ying, Oakey, Helena, Perkins, Griffith Boord, Nguyen, Trung, Binkowski, Sabrina, Bui, Minh, Choo, Ace Y. L., Gibson, Emily, Huang, Dexing, Kim, Ki Wook, Ngui, Katrina, Rawlinson, William D., Sadlon, Timothy, Couper, Jennifer J., Penno, Megan A. S., Barry, Simon C.

“…Background: Rural/remote blood collection can cause delays in processing, reducing PBMC number, viability, cell composition and function. To mitigate these…”
Get full text

2D-DIGE analysis of sera from transgenic mouse models reveals novel candidate protein biomarkers for human gastric cancer by Penno, Megan A.S., Klingler-Hoffmann, Manuela, Brazzatti, Julie A., Boussioutas, Alex, Putoczki, Tracy, Ernst, Matthias, Hoffmann, Peter

“…The gp130F/F genetically engineered mouse (GEM) model reproducibly and predictably develops a gastric adenoma phenotype resembling the primary lesions of human…”
Get full text

Experiences of Caregivers and At-Risk Children Enrolled in a Prospective Pregnancy-Birth Cohort Study into the Causes of Type 1 Diabetes: The ENDIA Study by McGorm, Kelly J, Brown, James D, Roberts, Alison G, Greenbank, Susan, Brasacchio, Daniella, Sawyer, Alyssa C P, Oakey, Helena, Colman, Peter G, Craig, Maria E, Davis, Elizabeth A, Soldatos, Georgia, Thomson, Rebecca L, Wentworth, John M, Couper, Jennifer J, Penno, Megan A S, On Behalf Of The Endia Study Group

“…We sought research experiences of caregivers and their children were enrolled in the Environmental Determinants of Islet Autoimmunity (ENDIA) study. ENDIA is a…”
Get full text

Environmental determinants of islet autoimmunity (ENDIA): a pregnancy to early life cohort study in children at-risk of type 1 diabetes by Penno, Megan A S, Couper, Jennifer J, Craig, Maria E, Colman, Peter G, Rawlinson, William D, Cotterill, Andrew M, Jones, Timothy W, Harrison, Leonard C

“…The incidence of type 1 diabetes has increased worldwide, particularly in younger children and those with lower genetic susceptibility. These observations…”
Get full text

Early-life factors contributing to type 1 diabetes by Craig, Maria E., Kim, Ki Wook, Isaacs, Sonia R., Penno, Megan A., Hamilton-Williams, Emma E., Couper, Jennifer J., Rawlinson, William D.

“…The incidence of type 1 diabetes has increased since the mid-twentieth century at a rate that is too rapid to be attributed to genetic predisposition alone…”
Get full text

Environmental Determinants of Islet Autoimmunity (ENDIA) longitudinal prospective pregnancy to childhood cohort study of Australian children at risk of type 1 diabetes: parental demographics and birth information by Thomson, Rebecca L, Oakey, Helena, Haynes, Aveni, Craig, Maria E, Harrison, Leonard C, Wentworth, John M, Anderson, Amanda, Ashwood, Pat, Barry, Simon, Brittain, Bek, Brown, James D, Colman, Peter G, Davis, Elizabeth A, Hamilton-Williams, Emma, Huynh, Dao, Huynh, Tony, Kim, Ki-Wook, McGorm, Kelly J, Morahan, Grant, Rawlinson, William, Sinnott, Richard O, Soldatos, Georgia, Tye-Din, Jason A, Vuillermin, Peter J, Penno, Megan A S, Couper, Jennifer J

“…IntroductionThe Environmental Determinants of Islet Autoimmunity (ENDIA) Study is an ongoing Australian prospective cohort study investigating how modifiable…”
Get full text

Gut microbiome dysbiosis and increased intestinal permeability in children with islet autoimmunity and type 1 diabetes: A prospective cohort study by Harbison, Jessica E., Roth‐Schulze, Alexandra J., Giles, Lynne C., Tran, Cuong D., Ngui, Katrina M., Penno, Megan A., Thomson, Rebecca L., Wentworth, John M., Colman, Peter G., Craig, Maria E., Morahan, Grant, Papenfuss, Anthony T., Barry, Simon C., Harrison, Leonard C., Couper, Jennifer J.

“…Aims/hypothesis To investigate the longitudinal relationship between the gut microbiome, circulating short chain fatty acids (SCFAs) and intestinal…”
Get full text

Identifying Candidate Serum Biomarkers of Exposure to Tunicamycins in Rats Using Two-Dimensional Electrophoresis by Penno, Megan A. S, Bacic, Antony, Colegate, Steven M, Hoffmann, Peter, Michalski, Wojtek P

“…A model for chronic corynetoxins poisoning has been established in rats exposed to the toxicologically bioequivalent inhibitor of N-linked glycosylation the…”
Get full text

Influence of fecal collection conditions and 16S rRNA gene sequencing at two centers on human gut microbiota analysis by Penington, Jocelyn Sietsma, Penno, Megan A. S., Ngui, Katrina M., Ajami, Nadim J., Roth-Schulze, Alexandra J., Wilcox, Stephen A., Bandala-Sanchez, Esther, Wentworth, John M., Barry, Simon C., Brown, Cheryl Y., Couper, Jennifer J., Petrosino, Joseph F., Papenfuss, Anthony T., Harrison, Leonard C.

“…To optimise fecal sampling for reproducible analysis of the gut microbiome, we compared different methods of sample collection and sequencing of 16S rRNA genes…”
Get full text

A Long-Term Evaluation of Facebook for Recruitment and Retention in the ENDIA Type 1 Diabetes Pregnancy-Birth Cohort Study by McGorm, Kelly J., Brown, James D., Thomson, Rebecca L., Oakey, Helena, Moore, Belinda, Hendry, Alexandra, Colman, Peter G., Craig, Maria E., Davis, Elizabeth A., Harris, Mark, Harrison, Leonard C., Haynes, Aveni, Soldatos, Georgia, Vuillermin, Peter, Wentworth, John M., Couper, Jennifer J., Penno, Megan A. S.

“…Background: The Environmental Determinants of Islet Autoimmunity (ENDIA) study is an Australia-wide pregnancy-birth cohort study following children who have a…”
Get full text

Women with type 1 diabetes exhibit a progressive increase in gut Saccharomyces cerevisiae in pregnancy associated with evidence of gut inflammation by Bandala-Sanchez, Esther, Roth-Schulze, Alexandra J., Oakey, Helena, Penno, Megan A.S., Bediaga, Naiara G., Naselli, Gaetano, Ngui, Katrina M., Smith, Alannah D., Huang, Dexing, Zozaya-Valdes, Enrique, Thomson, Rebecca L., Brown, James D., Vuillermin, Peter J., Barry, Simon C., Craig, Maria E., Rawlinson, William D., Davis, Elizabeth A., Harris, Mark, Soldatos, Georgia, Colman, Peter G., Wentworth, John M., Haynes, Aveni, Morahan, Grant, Sinnott, Richard O., Papenfuss, Anthony T., Couper, Jennifer J., Harrison, Leonard C.

“…Studies of the gut microbiome have focused on its bacterial composition. We aimed to characterize the gut fungal microbiome (mycobiome) across pregnancy in…”
Get full text

Changes in pancreatic exocrine function in young at‐risk children followed to islet autoimmunity and type 1 diabetes in the ENDIA study by Penno, Megan A.S., Oakey, Helena, Augustine, Priya, Taranto, Mario, Barry, Simon C., Colman, Peter G., Craig, Maria E., Davis, Elizabeth A., Giles, Lynne C., Harris, Mark, Haynes, Aveni, McGorm, Kelly, Morahan, Grant, Morbey, Claire, Rawlinson, William D., Sinnott, Richard O., Soldatos, Georgia, Thomson, Rebecca L., Vuillermin, Peter J., Wentworth, John M., Harrison, Leonard C., Couper, Jennifer J.

“…Backgrounds We aimed to monitor pancreatic exocrine function longitudinally in relation to the development of islet autoimmunity (IA) and type 1 diabetes (T1D)…”
Get full text

Associations between diet, the gut microbiome and short chain fatty acids in youth with islet autoimmunity and type 1 diabetes by Harbison, Jessica E., Thomson, Rebecca L., Wentworth, John M., Louise, Jennie, Roth‐Schulze, Alexandra, Battersby, Rachel J., Ngui, Katrina M., Penno, Megan A. S., Colman, Peter G., Craig, Maria E., Barry, Simon C., Tran, Cuong D., Makrides, Maria, Harrison, Leonard C., Couper, Jennifer J.

“…Aim We aimed to characterize associations between diet and the gut microbiome and short chain fatty acid (SCFA) products in youth with islet autoimmunity or…”
Get full text

Higher frequency of vertebrate‐infecting viruses in the gut of infants born to mothers with type 1 diabetes by Kim, Ki Wook, Allen, Digby W., Briese, Thomas, Couper, Jennifer J., Barry, Simon C., Colman, Peter G., Cotterill, Andrew M., Davis, Elizabeth A., Giles, Lynne C., Harrison, Leonard C., Harris, Mark, Haynes, Aveni, Horton, Jessica L., Isaacs, Sonia R., Jain, Komal, Lipkin, Walter I., McGorm, Kelly, Morahan, Grant, Morbey, Claire, Pang, Ignatius C. N., Papenfuss, Anthony T., Penno, Megan A. S., Sinnott, Richard O., Soldatos, Georgia, Thomson, Rebecca L., Vuillermin, Peter, Wentworth, John M., Wilkins, Marc R., Rawlinson, William D., Craig, Maria E.

“…Background Microbial exposures in utero and early life shape the infant microbiome, which can profoundly impact on health. Compared to the bacterial…”
Get full text

Distinct Gut Virome Profile of Pregnant Women With Type 1 Diabetes in the ENDIA Study by Wook Kim, Ki, Allen, Digby W, Briese, Thomas, Couper, Jennifer J, Barry, Simon C, Colman, Peter G, Cotterill, Andrew M, Davis, Elizabeth A, Giles, Lynne C, Harrison, Leonard C, Harris, Mark, Haynes, Aveni, Horton, Jessica L, Isaacs, Sonia R, Jain, Komal, Lipkin, Walter Ian, Morahan, Grant, Morbey, Claire, Pang, Ignatius C N, Papenfuss, Anthony T, Penno, Megan A S, Sinnott, Richard O, Soldatos, Georgia, Thomson, Rebecca L, Vuillermin, Peter J, Wentworth, John M, Wilkins, Marc R, Rawlinson, William D, Craig, Maria E

“…Abstract Background The importance of gut bacteria in human physiology, immune regulation, and disease pathogenesis is well established. In contrast, the…”
Get full text

Optimal preparation methods for automated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry profiling of low molecular weight proteins and peptides by Penno, Megan A. S., Ernst, Matthias, Hoffmann, Peter

“…Mass spectrometry (MS) profiling of the proteome and peptidome for disease‐associated patterns is a new concept in clinical diagnostics. The technique,…”
Get full text