Search Results - "Pennington, Edward Ross"

The role of cardiolipin concentration and acyl chain composition on mitochondrial inner membrane molecular organization and function by Pennington, Edward Ross, Funai, Katsuhiko, Brown, David A., Shaikh, Saame Raza

“…Cardiolipin (CL) is a key phospholipid of the mitochondria. A loss of CL content and remodeling of CL's acyl chains is observed in several pathologies. Strong…”
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17β-Estradiol Directly Lowers Mitochondrial Membrane Microviscosity and Improves Bioenergetic Function in Skeletal Muscle by Torres, Maria J., Kew, Kim A., Ryan, Terence E., Pennington, Edward Ross, Lin, Chien-Te, Buddo, Katherine A., Fix, Amy M., Smith, Cheryl A., Gilliam, Laura A., Karvinen, Sira, Lowe, Dawn A., Spangenburg, Espen E., Zeczycki, Tonya N., Shaikh, Saame Raza, Neufer, P. Darrell

“…Menopause results in a progressive decline in 17β-estradiol (E2) levels, increased adiposity, decreased insulin sensitivity, and a higher risk for type 2…”
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Mechanisms by Which Dietary Fatty Acids Regulate Mitochondrial Structure-Function in Health and Disease by Sullivan, E Madison, Pennington, Edward Ross, Green, William D, Beck, Melinda A, Brown, David A, Shaikh, Saame Raza

“…Mitochondria are the energy-producing organelles within a cell. Furthermore, mitochondria have a role in maintaining cellular homeostasis and proper calcium…”
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Docosahexaenoic acid lowers cardiac mitochondrial enzyme activity by replacing linoleic acid in the phospholipidome by Sullivan, E. Madison, Pennington, Edward Ross, Sparagna, Genevieve C., Torres, Maria J., Neufer, P. Darrell, Harris, Mitchel, Washington, James, Anderson, Ethan J., Zeczycki, Tonya N., Brown, David A., Shaikh, Saame Raza

“…Cardiac mitochondrial phospholipid acyl chains regulate respiratory enzymatic activity. In several diseases, the rodent cardiac phospholipidome is extensively…”
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Distinct membrane properties are differentially influenced by cardiolipin content and acyl chain composition in biomimetic membranes by Pennington, Edward Ross, Fix, Amy, Sullivan, E. Madison, Brown, David A., Kennedy, Anthony, Shaikh, Saame Raza

“…Cardiolipin (CL) has a critical role in maintaining mitochondrial inner membrane structure. In several conditions such as heart failure and aging, there is…”
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Conservation of chemically degraded waterlogged wood with sugars by Kennedy, Anthony, Pennington, Edward Ross

“…The effectiveness of two non-reducing sugars, both analogues of sucrose, to conserve degraded waterlogged wood was examined. The two sugars examined are…”
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OxPAPC stabilizes liquid-ordered domains in biomimetic membranes by Cavazos, Andres T., Pennington, Edward Ross, Dadoo, Sahil, Gowdy, Kymberly M., Wassall, Stephen R., Shaikh, Saame Raza

“…Long-chain polyunsaturated fatty acids (PUFAs) are prone to nonenzymatic oxidation in response to differing environmental stressors and endogenous cellular…”
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Docosahexaenoic acid regulates the formation of lipid rafts: A unified view from experiment and simulation by Wassall, Stephen R., Leng, Xiaoling, Canner, Samuel W., Pennington, Edward Ross, Kinnun, Jacob J., Cavazos, Andres T., Dadoo, Sahil, Johnson, Dylan, Heberle, Frederick A., Katsaras, John, Shaikh, Saame Raza

“…Docosahexaenoic acid (DHA, 22:6) is an n−3 polyunsaturated fatty acid (n−3 PUFA) that influences immunological, metabolic, and neurological responses through…”
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Mechanical strength studies on degraded waterlogged wood treated with sugars by Tahira, Adeem, Howard, William, Pennington, Edward Ross, Kennedy, Anthony

“…This study aims to measure the mechanical strength of chemically degraded wood samples and compare the values obtained with fresh wood and degraded wood…”
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The prohibitin complex regulates macrophage fatty acid composition, plasma membrane packing, and lipid raft-mediated inflammatory signaling by Matthews, Christine E. Psaltis, Fussner, Lynn A., Yaeger, Michael, Aloor, Jim J., Reece, Sky W., Kilburg-Basnyat, Brita J., Varikuti, Sanjay, Luo, Bin, Inks, Morgan, Sergin, Selin, Schmidt, Cameron A., Neufer, P. Darrell, Pennington, Edward Ross, Fisher-Wellman, Kelsey H., Chowdhury, Saiful M., Fessler, Michael B., Fenton, Jenifer I., Anderson, Ethan J., Shaikh, Saame Raza, Gowdy, Kymberly M.

“…•Role of prohibitins (PHBs) in macrophage signaling was studied using PHB knockdown.•PHB knockdown decreases expression and signaling of lipid raft-dependent…”
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Proteolipid domains form in biomimetic and cardiac mitochondrial vesicles and are regulated by cardiolipin concentration but not monolyso-cardiolipin by Pennington, Edward Ross, Sullivan, E. Madison, Fix, Amy, Dadoo, Sahil, Zeczycki, Tonya N., DeSantis, Anita, Schlattner, Uwe, Coleman, Rosalind A., Chicco, Adam J., Brown, David A., Shaikh, Saame Raza

“…Cardiolipin (CL) is an anionic phospholipid mainly located in the inner mitochondrial membrane, where it helps regulate bioenergetics, membrane structure, and…”
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The cardiolipin-binding peptide elamipretide mitigates fragmentation of cristae networks following cardiac ischemia reperfusion in rats by Allen, Mitchell E., Pennington, Edward Ross, Perry, Justin B., Dadoo, Sahil, Makrecka-Kuka, Marina, Dambrova, Maija, Moukdar, Fatiha, Patel, Hetal D., Han, Xianlin, Kidd, Grahame K., Benson, Emily K., Raisch, Tristan B., Poelzing, Steven, Brown, David A., Shaikh, Saame Raza

“…Mitochondrial dysfunction contributes to cardiac pathologies. Barriers to new therapies include an incomplete understanding of underlying molecular culprits…”
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Discriminating between Cardiolipin Content and Cardiolipin Acyl Chain Composition on Mitochondrial Inner Membrane Biophysical Organization by Pennington, Edward Ross

“…The pathogenesis of cardiovascular diseases (CVDs) is driven, in part, from impairment in myocardial energy metabolism. There is convincing evidence that…”
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A Calorimetric and Spectroscopic Study of the Interactions Between Model Lipid Membrane Bilayers and Simple Sugars by Pennington, Edward Ross

“…It is well known that various organisms, such as the tardigrade, naturally use carbohydrates, particularly disaccharides, to help preserve their cell…”
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