Search Results - "Penner, J D"

A novel Mycoplasma sp. associated with proliferative tracheitis and pneumonia in a burmese python ( Python molurus bivittatus) by Penner, J.D., Jacobson, E.R., Brown, D.R., Adams, H.P., Besch-Williford, C.L.

“…Proliferative lymphocytic tracheitis and pneumonia were observed histologically in the respiratory tract of a captive Burmese python ( Python molurus…”
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Firm and environmental influences on the mode and sequence of foreign research and development activities by Penner-Hahn, Joan D.

“…This paper develops an explanation for the mode and sequence of entry that firms select for their international research and development activities. The…”
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Derivation of retinoic acid and metabolites from a teratogenic dose of retinol (vitamin A) in mice by Kochhar, D M, Penner, J D, Satre, M A

“…Megadose supplements of vitamin A are under suspicion as hazards to the developing embryo after the discovery that two vitamin A-related drugs, Accutane and…”
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Diminished teratogenicity of retinoid X receptor-selective synthetic retinoids by Jiang, Heng, Penner, John D., Beard, Richard L., Chandraratna, Roshantha A.S., Kochhar, Devendra M.

“…One feature that contraindicates the wide therapeutic use of retinoids is their teratogenicity. Synthetic retinoids are distinguishable from each other on the…”
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Modulation of limb bud chondrogenesis by retinoic acid and retinoic acid receptors by Jiang, H, Soprano, D R, Li, S W, Soprano, K J, Penner, J D, Gyda, 3rd, M, Kochhar, D M

“…An excess of retinoic acid (RA) in the mouse embryo in utero produces hypochondrogenesis and severe limb bone deformities. Since one of the RA…”
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Biotransformation of etretinate and developmental toxicity of etretin and other aromatic retinoids in teratogenesis bioassays by Kochhar, D M, Penner, J D, Minutella, L M

“…Developmental toxicity of the anti-psoriatic drug etretinate (Tegison) and some features of its metabolic conversion to etretin and isoetretin were…”
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A comparison of methods to predict minimal weight in high school wrestlers by Clark, R R, Kuta, J M, Sullivan, J C, Bedford, W M, Penner, J D, Studesville, E A

“…The purpose of this study was to compare the accuracy of body fat determinations and subsequent calculation of minimal weight (MW) by dual energy x-ray…”
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Angiotensin II receptors in the lumbar spinal cord of the rat by White, S R, Penner, J D, Speth, R C, Chan, J Y

“…Locations of cells responsive to microiontophoretically applied angiotensin II (AII) were compared to distributions of AII receptor binding sites identified by…”
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Fibroblasts of fawn-hooded rats by Penner, J D, Prieur, D J

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The use of a retinoid receptor antagonist in a new model to study vitamin A-dependent developmental events by Kochhar, D M, Jiang, H, Penner, J D, Johnson, A T, Chandraratna, R A

“…Multiple fetal anomalies occur in vitamin A deficient animals as well as in retinoic acid receptor gene 'knockout' mice, indicating that retinoic acid (an…”
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Developmental effects of isotretinoin and 4-oxo-isotretinoin: the role of metabolism in teratogenicity by Kochhar, D M, Penner, J D

“…Previous observations have indicated that isotretinoin (IT), a drug in common use for therapy of cystic acne, is teratogenic in humans but possesses low…”
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Developmental toxicity of purified fumonisin B1 in pregnant Syrian hamsters by Penner, Jocelyn D., Casteel, Stan W., Pittman Jr, Louis, Rottinghaus, George E., Wyatt, Roger D.

“…The purpose of this study was to characterize the developmental toxicity of fumonisin B1 (FB1), a mycotoxin produced by Fusarium moniliforme, on fetal Syrian…”
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Differential teratogenic response of mouse embryos to receptor selective analogs of retinoic acid by Kochhar, Devendra M., Jiang, Heng, Penner, John D., Beard, Richard L., Chandraratna, Roshantha A.S.

“…Early events that initiate teratogenesis by Accutane ® or other retinoids in mammalian embryos remain unknown. It would be helpful for mechanistic…”
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A comparative study of the lesions in cultured fibroblasts of humans and four species of animals with Chediak-Higashi syndrome by Penner, J D, Prieur, D J

“…The Chediak-Higashi syndrome (CHS) is an autosomal recessive genetic disease of humans, and clinically similar diseases occur in cats, mink, cattle, mice,…”
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Placental transfer and developmental effects of 9-cis retinoic acid in mice by Kochhar, D M, Jiang, H, Penner, J D, Heyman, R A

“…9-cis retinoic acid (RA) is a naturally occurring isomer of all-trans RA. While both isomers can bind with high affinity and activate RA receptors, only 9-cis…”
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Analysis of high dysmorphogenic activity of Ro 13-6307, a tetramethylated tetralin analog of retinoic acid by Kochhar, D M, Penner, J D

“…Certain synthetic retinoids differ widely from retinoic acid (RA) in teratogenic potency, being much more or much less effective than RA. It is assumed that…”
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Pharmacokinetic assessment of teratologically effective concentrations of an endogenous retinoic acid metabolite by Satre, M A, Penner, J D, Kochhar, D M

“…Retinoic acid is a natural vitamin A derivative that undergoes oxidative metabolism in the body to yield several metabolites, which apparently represent the…”
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Comparative teratogenic activities of two retinoids: effects on palate and limb development by Kochhar, D M, Penner, J D, Tellone, C I

“…Two closely related retinoids, all-trans and 13-cis retinoic acids, were assessed for their relative activities as teratogens in ICR mice by monitoring the…”
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Retinamides: hydrolytic conversion of retinoylglycine to retinoic acid in pregnant mice contributes to teratogenicity by Kochhar, D M, Shealy, Y F, Penner, J D, Jiang, H

“…Retinamides are prominent among synthetic vitamin A derivatives (retinoids) which can prevent or reduce the incidence of certain carcinogen-induced neoplasms…”
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Retinoic acid enhances the displacement of newly synthesized hyaluronate from cell layer to culture medium during early phases of chondrogenesis by Kochhar, D M, Penner, J D, Hickey, T

“…Chondrogenic differentiation in mouse limb bud mesenchymal cells cultured at high density was suppressed by supplementation of the medium with retinoic acid (1…”
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