Search Results - "Pennella, Mario A."
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Adenovirus E1B 55-Kilodalton Protein Is a p53-SUMO1 E3 Ligase That Represses p53 and Stimulates Its Nuclear Export through Interactions with Promyelocytic Leukemia Nuclear Bodies
Published in Journal of Virology (01-12-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Structural determinants of metal selectivity in prokaryotic metal-responsive transcriptional regulators
Published in Biometals (01-08-2005)“…Metal ion homeostasis in prokaryotes is maintained by metal-responsive transcriptional regulatory proteins that regulate the transcription of genes encoding…”
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Tandem SAM Domain Structure of Human Caskin1: A Presynaptic, Self-Assembling Scaffold for CASK
Published in Structure (London) (07-12-2011)“…The synaptic scaffolding proteins CASK and Caskin1 are part of the fibrous mesh of proteins that organize the active zones of neural synapses. CASK binds to a…”
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Complexity in transcription control at the activation domain-mediator interface
Published in Science signaling (05-05-2009)“…Transcript elongation by polymerase II paused at the Egr1 promoter is activated by mitogen-activated protein kinase phosphorylation of the ternary complex…”
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Structural Elements of Metal Selectivity in Metal Sensor Proteins
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-2003)“…Staphylococcus aureus CzrA and Mycobacterium tuberculosis NmtR are homologous zinc/cobalt-responsive and nickel/cobalt-responsive transcriptional repressors in…”
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Adenovirus E1A Activation Domain Regulates H3 Acetylation Affecting Varied Steps in Transcription at Different Viral Promoters
Published in Journal of virology (15-09-2018)“…How histone acetylation promotes transcription is not clearly understood. Here, we confirm an interaction between p300 and the adenovirus 2 large E1A…”
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The SmtB/ArsR family of metalloregulatory transcriptional repressors: structural insights into prokaryotic metal resistance
Published in FEMS microbiology reviews (01-06-2003)“…The SmtB/ArsR family of prokaryotic metalloregulatory transcriptional repressors represses the expression of operons linked to stress-inducing concentrations…”
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Individual Metal Ligands Play Distinct Functional Roles in the Zinc Sensor Staphylococcus aureus CzrA
Published in Journal of molecular biology (10-03-2006)“…Recent studies on metalloregulatory proteins suggest that coordination number/geometry and metal ion availability in a host cytosol are key determinants for…”
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A Metal–Ligand-mediated Intersubunit Allosteric Switch in Related SmtB/ArsR Zinc Sensor Proteins
Published in Journal of molecular biology (31-10-2003)“…The origin of metal ion selectivity by members of the SmtB/ArsR family of bacterial metal-sensing transcriptional repressors and the mechanism of negative…”
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A nickel-cobalt-sensing ArsR-SmtB family repressor. Contributions of cytosol and effector binding sites to metal selectivity
Published in The Journal of biological chemistry (11-10-2002)“…NmtR from Mycobacterium tuberculosis is a new member of the ArsR-SmtB family of metal sensor transcriptional repressors. NmtR binds to the operator-promoter of…”
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Resonance assignments of the metal sensor CzrA in the apo-, Zn2- and DNA-bound (42 kDa) states
Published in Biomolecular NMR assignments (01-07-2007)“…Zn/Co binding to homodimeric CzrA de-represses transcription of the czr (cobalt zinc resistance) operon in Staphylococcus aureus. Essentially complete backbone…”
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Conformational Heterogeneity in the C-terminal Zinc Fingers of Human MTF-1
Published in The Journal of biological chemistry (09-11-2001)“…The human metalloregulatory transcription factor, metal-response element (MRE)-binding transcription factor-1 (MTF-1), contains six TFIIIA-type Cys2-His2…”
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A Nickel-Cobalt-sensing ArsR-SmtB Family Repressor
Published in The Journal of biological chemistry (11-10-2002)“…NmtR from Mycobacterium tuberculosisis a new member of the ArsR-SmtB family of metal sensor transcriptional repressors. NmtR binds to the operator-promoter of…”
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Dominant-negative mechanism of leukemogenic PAX5 fusions
Published in Oncogene (23-02-2012)“…PAX5 encodes a master regulator of B-cell development. It fuses to other genes associated with acute lymphoblastoid leukemia (ALL). These fusion products are…”
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Conformational heterogeneity in the C-terminal zinc fingers of human MTF-1: an NMR and zinc-binding study
Published in The Journal of biological chemistry (09-11-2001)“…The human metalloregulatory transcription factor, metal-response element (MRE)-binding transcription factor-1 (MTF-1), contains six TFIIIA-type Cys(2)-His(2)…”
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Resonance assignments of the metal sensor CzrA in the apo-, Zn sub(2)- and DNA-bound (42kDa) states
Published in Biomolecular NMR assignments (01-07-2007)“…Zn/Co binding to homodimeric CzrA de-represses transcription of the czr (cobalt zinc resistance) operon in Staphylococcus aureus. Essentially complete backbone…”
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