Search Results - "Penn, S. J."

A novel angiopoietin‐derived peptide displays anti‐angiogenic activity and inhibits tumour‐induced and retinal neovascularization by Palmer, GM, Tiran, Z, Zhou, Z, Capozzi, ME, Park, W, Coletta, C, Pyriochou, A, Kliger, Y, Levy, O, Borukhov, I, Dewhirst, MW, Rotman, G, Penn, JS, Papapetropoulos, A

“…BACKGROUND AND PURPOSE Pathological angiogenesis is associated with various human diseases, such as cancer, autoimmune diseases and retinopathy. The…”
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Vascular endothelial growth factor in eye disease by Penn, J.S., Madan, A., Caldwell, R.B., Bartoli, M., Caldwell, R.W., Hartnett, M.E.

“…Collectively, angiogenic ocular conditions represent the leading cause of irreversible vision loss in developed countries. In the US, for example, retinopathy…”
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Dielectric loss of oxide single crystals and polycrystalline analogues from 10 to 320 K by Alford, N.McN, Breeze, J., Wang, X., Penn, S.J., Dalla, S., Webb, S.J., Ljepojevic, N., Aupi, X.

“…The key factors influencing microwave dielectric loss are examined. A comparison is made between single crystals and polycrystalline analogues. Measurements of…”
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The Effect of an Angiostatic Steroid on Neovascularization in a Rat Model of Retinopathy of Prematurity by Penn, John S, Rajaratnam, Veeraramani S, Collier, Robert J, Clark, Abbot F

“…The inhibition of angiogenesis by angiostatic steroids has been demonstrated in a variety of systems, including rabbit and rat cornea. There is considerable…”
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Variable oxygen exposure causes preretinal neovascularization in the newborn rat by Penn, JS, Tolman, BL, Lowery, LA

“…To test the hypothesis that variable hyperoxia potentiates preretinal neovascularization in newborn rats, and to establish a more reliable animal model of ROP…”
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The range of PaO2 variation determines the severity of oxygen-induced retinopathy in newborn rats by Penn, JS, Henry, MM, Wall, PT, Tolman, BL

“…This study was conducted to determine the potential influence of PaO2 fluctuation on the retinal neovascular response known to occur in newborn rats exposed to…”
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Ambient Hypoxia Reverses Retinal Vascular Attenuation in a Transgenic Mouse Model of Autosomal Dominant Retinitis Pigmentosa by Penn, John S, Li, Shihong, Naash, Muna I

“…Loss of retinal capillaries is an inherent component of late stage autosomal dominant retinitis pigmentosa (ADRP). This study examined the hypothetical role of…”
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Exposure to alternating hypoxia and hyperoxia causes severe proliferative retinopathy in the newborn rat by PENN, J. S, HENRY, M. M, TOLMAN, B. L

“…Exposure to variable hyperoxia has recently been shown to be much more effective at producing proliferative retinopathy in the newborn rat than exposure to…”
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Inhibition of Retinal Angiogenesis by Peptides Derived from Thrombospondin-1 by Shafiee, Afshin, Penn, John S, Krutzsch, Henry C, Inman, John K, Roberts, David D, Blake, Diane A

“…Thrombospondin (TSP)1 is a tumor suppressor with activity that is associated with its ability to inhibit neovascularization. Previous studies have mapped this…”
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Oxygen-induced retinopathy in the rat: relationship of retinal nonperfusion to subsequent neovascularization by Penn, JS, Tolman, BL, Henry, MM

“…To confirm a relationship between oxygen-induced retinal vasoattenuation and subsequent abnormal neovascularization in the newborn rat. Beginning at birth,…”
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Impaired hyaloidal circulation function and uncoordinated ocular growth patterns in experimental retinopathy of prematurity by Berkowitz, BA, Lukaszew, RA, Mullins, CM, Penn, JS

“…To test the hypotheses that, in the newborn rat model of retinopathy of prematurity (ROP), the hyaloidal circulation is functionally impaired and its…”
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Abnormal panretinal response pattern to carbogen inhalation in experimental retinopathy of prematurity by BERKOWITZ, B. A, PENN, J. S

“…Present technologies are not able to determine which retinas are at risk for the development of neovascularization in retinopathy of prematurity (ROP). In this…”
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Therapeutic effect of liposomal superoxide dismutase in an animal model of retinopathy of prematurity by NIESMAN, M. R, JOHNSON, K. A, PENN, J. S

“…A newborn rat model of retinopathy of prematurity was used to test the hypothesis that a lack of superoxide dismutase contributes to the retinal…”
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Oxygen-induced retinopathy in the rat. Vitamins C and E as potential therapies by Penn, JS, Thum, LA, Naash, MI

“…Oxygen-induced retinopathy (OIR) was produced by subjecting newborn albino rats to a 60% oxygen atmosphere for 14 days before they were killed and retinal…”
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Effect of Porosity and Grain Size on the Microwave Dielectric Properties of Sintered Alumina by Penn, Stuart J., Alford, Neil McN, Templeton, Alan, Wang, Xiaoru, Xu, Meishing, Reece, Michael, Schrapel, Kevin

“…The real part of the permittivity (ε) and the tan δ of sintered alumina (Al2O3) at about 9 GHz have been measured. The dielectric properties have been examined…”
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Microwave Dielectric Loss of Titanium Oxide by Templeton, Alan, Wang, Xiaoru, Penn, Stuart J., Webb, Stephen J., Cohen, Lesley F., Alford, Neil McN

“…The dielectric loss (tan δ) of titanium dioxide (TiO2) disks has been measured at a frequency of 3 GHz. High‐purity TiO2 sintered to almost‐full density…”
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Anisotropic and cyclic mechanical properties of piezoelectrics—compression testing by Calderon Moreno, J.M, Guiu, F, Meredith, M, Reece, M.J, Alford, N.McN, Penn, S.J

“…The mechanical stressing of PZT produces irreversible deformation by the irreversible switching of 90° domains. This leads to highly anisotropic deformation…”
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Expression of Protein Kinase CK2 in Astroglial Cells of Normal and Neovascularized Retina by Kramerov, Andrei A., Saghizadeh, Mehrnoosh, Pan, Hao, Kabosova, Andrea, Montenarh, Mathias, Ahmed, Khalil, Penn, John S., Chan, Candy K., Hinton, David R., Grant, Maria B., Ljubimov, Alexander V.

“…We previously documented protein kinase CK2 involvement in retinal neovascularization. Here we describe retinal CK2 expression and combined effects of CK2…”
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Effects of oxygen rearing on the electroretinogram and GFA-protein in the rat by Penn, JS, Thum, LA, Rhem, MN, Dell, SJ

“…Albino rats were maintained in 60% oxygen from birth through 14 days of age. Control rats were simultaneously maintained in room air. At the end of the…”
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Photostasis: regulation of daily photon-catch by rat retinas in response to various cyclic illuminances by Penn, J S, Williams, T P

“…Albino rats were born and raised in 12 hr light: 12 hr dark regimes of illuminances varying from 3- to 800 lx. At 15 weeks of age, the animals were killed and…”
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