Search Results - "Penke, B"

Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic mice by Oksman, M., Iivonen, H., Hogyes, E., Amtul, Z., Penke, B., Leenders, I., Broersen, L., Lütjohann, D., Hartmann, T., Tanila, H.

“…The present study assessed the influence of dietary lipids on accumulation of amyloid beta-peptide (Aβ) in the brain. Seven experimental diets with varying…”
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S1R agonist modulates rat platelet eicosanoid synthesis and aggregation by Váczi, Sándor, Barna, L., Harazin, A., Mészáros, M., Porkoláb, G., Zvara, Á., Ónody, R., Földesi, I., Veszelka, S., Penke, B., Fülöp, L., Deli, M. A., Mezei, Z.

“…Sigma-1 receptor (S1R) is detected in different cell types and can regulate intracellular signaling pathways. S1R plays a role in the pathomechanism of…”
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Functionalization of gold nanoparticles with amino acid, β-amyloid peptides and fragment by Majzik, A., Fülöp, L., Csapó, E., Bogár, F., Martinek, T., Penke, B., Bíró, G., Dékány, I.

“…Gold nanoparticles (Au NPs) were functionalized by cysteine ( Cys), β-amyloid peptides ( Cys 0 Aβ 1-28 , Cys 0 Aβ 1-40 , Aβ 1-42 ) and a pentapeptide fragment…”
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The LPS receptor (CD14) links innate immunity with Alzheimer's disease by Fassbender, K., Walter, S., Kühl, S., Landmann, R., Ishii, K., Bertsch, T., Stalder, A.K., Muehlhauser, F., Liu, Y., Ulmer, A.J., Rivest, S., Lentschat, A., Gulbins, E., Jucker, M., Staufenbiel, M., Brechtel, K., Walter, J., Multhaup, G., Penke, B., Adachi, Y., Hartmann, T., Beyreuther, K.

“…ABSTRACT To rapidly respond to invading microorganisms, humans call on their innate immune system. This occurs by microbe‐detecting receptors, such as CD14,…”
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Kynurenine metabolism in multiple sclerosis by Hartai, Z., Klivenyi, P., Janaky, T., Penke, B., Dux, L., Vecsei, L.

“…Objective –  Excitatory amino acid receptors are involved in the normal physiology of the brain, and may play a role in the pathogenesis of neurological…”
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β-Amyloid pathology in the entorhinal cortex of rats induces memory deficits: Implications for Alzheimer’s disease by Sipos, E, Kurunczi, A, Kasza, Á, Horváth, J, Felszeghy, K, Laroche, S, Toldi, J, Párducz, Á, Penke, B, Penke, Z

“…Abstract Alzheimer’s disease is characterized by the presence of senile plaques in the brain, composed mainly of aggregated amyloid-β peptide (Aβ), which plays…”
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β-Amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis by Harkany, T., Ábrahám, I., Timmerman, W., Laskay, G., Tóth, B., Sasvári, M., Kónya, C., Sebens, J. B., Korf, J., Nyakas, C., Zarándi, M., Soós, K., Penke, B., Luiten, P. G. M.

“…Whereas a cardinal role for β‐amyloid protein (Aβ) has been postulated as a major trigger of neuronal injury in Alzheimer's disease, the pathogenic mechanism…”
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Membrane translocation of penetratin and its derivatives in different cell lines by Letoha, T., Gaál, S., Somlai, C., Czajlik, A., Perczel, A., Penke, B.

“…The third helix of the homeodomain of the Antennapedia homeoprotein can translocate through the cell membrane into the nucleus and can be used as an…”
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Neuroprotective effect of developmental docosahexaenoic acid supplement against excitotoxic brain damage in infant rats by Hgyes, E, Nyakas, C, Kiliaan, A, Farkas, T, Penke, B, Luiten, P.G.M

“…Long-chain polyunsaturated fatty acid (LC-PUFA) composition of neural membranes is a key factor for brain development, in chemical communication of neurons and…”
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A Modified, Optimized Kinetic Photometric Assay for the Determination of Blood Coagulation Factor XIII Activity in Plasma by Karpati, Levente, Penke, Botond, Katona, Eva, Balogh, Istvan, Vamosi, Gyorgy, Muszbek, Laszlo

“…Blood coagulation factor XIII (FXIII) is a zymogen that is transformed into an active transglutaminase by thrombin and Ca(2+). FXIII plays an essential role in…”
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Effect of Lysine-28 Side-Chain Acetylation on the Nanomechanical Behavior of Alzheimer Amyloid β25−35 Fibrils by Karsai, Á, Nagy, A, Kengyel, A, Mártonfalvi, Z, Grama, L, Penke, B, Kellermayer, M. S. Z

“…Amyloid fibrils are self-associating filamentous structures formed from the 39- to 42-residue-long amyloid β peptide (Aβ peptide). The deposition of Aβ fibrils…”
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N-Methyl-D-aspartate receptor antagonist MK-801 and radical scavengers protect cholinergic nucleus basalis neurons against beta-amyloid neurotoxicity by Harkany, T, Mulder, J, Sasvári, M, Abrahám, I, Kónya, C, Zarándi, M, Penke, B, Luiten, P G, Nyakas, C

“…Previous experimental data indicate the involvement of Ca(2+)-related excitotoxic processes, possibly mediated by N-Methyl-D-Aspartate (NMDA) receptors, in…”
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Mechanisms of beta-amyloid neurotoxicity: perspectives of pharmacotherapy by Harkany, T, Abrahám, I, Kónya, C, Nyakas, C, Zarándi, M, Penke, B, Luiten, P G

“…One of the characteristic neuropathological hallmarks of Alzheimer's disease (AD) is the extracellular accumulation of beta-amyloid peptides (Abeta) in…”
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Characterization of the Conformational Probability of N-Acetyl-Phenylalanyl-NH2 by RHF, DFT, and MP2 Computation and AIM Analyses, Confirmed by Jet-Cooled Infrared Data by Chass, Gregory A, Mirasol, Reinard S, Setiadi, David H, Tang, Ting-Hua, Chin, Wutharath, Mons, Michel, Dimicoli, Iliana, Dognon, Jean-Pierre, Viskolcz, Bela, Lovas, Sándor, Penke, Botond, Csizmadia, Imre G

“…Computational and experimental determinations were carried out in parallel on the conformational probability of N-Acetyl-Phenylalanine-NH2 (NAPA). Ab initio…”
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Investigation of penetratin peptides. Part 2. In vitro uptake of penetratin and two of its derivatives by Letoha, Tamás, Gaál, Szilvia, Somlai, Csaba, Venkei, Zsolt, Glavinas, Hristos, Kusz, Erzsébet, Duda, Ernö, Czajlik, András, Peták, Ferenc, Penke, Botond

“…As endocytic uptake of the Antennapedia homeodomain‐derived penetratin peptide (RQIKIWFQNRRMKWKK) is finally being revealed, some of the early views about…”
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Chronic Corticosterone Administration Dose-Dependently Modulates Aβ(1-42)− and NMDA-Induced Neurodegeneration in Rat Magnocellular Nucleus Basalis by Abrahám, I., Harkany, T., Horvath, K. M., Veenema, A. H., Penke, B., Nyakas, C., Luiten, P. G. M.

“…The impact of glucocorticoids on β‐amyloid(1–42) (Aβ(1–42)) and NMDA‐induced neurodegeneration was investigated in vivo. Aβ(1–42) or NMDA was injected into the…”
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Pentapeptides derived from Aβ1–42 protect neurons from the modulatory effect of Aβ fibrils—an in vitro and in vivo electrophysiological study by Szegedi, V., Fülöp, L., Farkas, T., Rózsa, E., Robotka, H., Kis, Z., Penke, Z., Horváth, S., Molnár, Z., Datki, Z., Soós, K., Toldi, J., Budai, D., Zarándi, M., Penke, B.

“…Short fragments and fragment analogues of beta-amyloid 1–42 peptide (Aβ1–42) display a protective effect against Aβ-mediated neurotoxicity. After consideration…”
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Density functional study of infinite polyserine chains by Bogár, F, Szekeres, Zs, Bartha, F, Penke, B, Ladik, J

“…Two different helical conformations (alpha and 3-10 helices) of polyserine are studied using density functional theory. The infinite system characterized by…”
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Comparative study of sub-micrometer polymeric structures: Dot-arrays, linear and crossed gratings generated by UV laser based two-beam interference, as surfaces for SPR and AFM based bio-sensing by Csete, M., Sipos, Á., Kőházi-Kis, A., Szalai, A., Szekeres, G., Mathesz, A., Csákó, T., Osvay, K., Bor, Zs, Penke, B., Deli, M.A., Veszelka, Sz, Schmatulla, A., Marti, O.

“…Two-dimensional gratings are generated on poly-carbonate films spin-coated onto thin gold–silver bimetallic layers by two-beam interference method…”
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Comparison of HF, HF + MP2, LDA, BLYP, and B3LYP band structures of the homopolypeptides by Ladik, J., Bogar, F., Penke, B.

“…Ab initio HF, HF + MP2, LDA DFT, BLYP DFT, and B3LYP DFT calculations are compared in the case of 19 homopolypeptides in their β pleated sheet conformation…”
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