Search Results - "Penicaud, Luc"
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Autonomic nervous system and pancreatic islet blood flow
Published in Biochimie (01-12-2017)“…Vascularization and innervation of the islet of Langerhans are highly interconnected and are critical for intercellular and intertissular communication. They…”
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Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion
Published in Diabetes (New York, N.Y.) (01-03-2009)“…Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion Corinne Leloup 1 , Cécile Tourrel-Cuzin 2 , Christophe…”
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High‐fat diet‐induced metabolic disorders impairs 5‐HT function and anxiety‐like behavior in mice
Published in British journal of pharmacology (01-07-2016)“…Background and Purpose The link between type 2 diabetes mellitus (T2DM) and depression is bidirectional. However, the possibility that metabolic disorders may…”
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Metformin Promotes Anxiolytic and Antidepressant-Like Responses in Insulin-Resistant Mice by Decreasing Circulating Branched-Chain Amino Acids
Published in The Journal of neuroscience (24-07-2019)“…Epidemiological studies indicate that insulin resistance (IR), a hallmark of type 2 diabetes, is associated with an increased risk of major depression. Here,…”
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Gut Commensal E. coli Proteins Activate Host Satiety Pathways following Nutrient-Induced Bacterial Growth
Published in Cell metabolism (09-02-2016)“…The composition of gut microbiota has been associated with host metabolic phenotypes, but it is not known if gut bacteria may influence host appetite. Here we…”
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COVID 19-Induced Smell and Taste Impairments: Putative Impact on Physiology
Published in Frontiers in physiology (26-01-2021)“…Smell and taste impairments are recognized as common symptoms in COVID 19 patients even in an asymptomatic phase. Indeed, depending on the country, in up to…”
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Brain Glucagon-Like Peptide-1 Regulates Arterial Blood Flow, Heart Rate, and Insulin Sensitivity
Published in Diabetes (New York, N.Y.) (01-10-2008)“…Brain Glucagon-Like Peptide-1 Regulates Arterial Blood Flow, Heart Rate, and Insulin Sensitivity Cendrine Cabou 1 2 3 , Gérard Campistron 1 2 3 , Nicolas…”
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Taste of Fat and Obesity: Different Hypotheses and Our Point of View
Published in Nutrients (27-01-2022)“…Obesity results from a temporary or prolonged positive energy balance due to an alteration in the homeostatic feedback of energy balance. Food, with its…”
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The gliotransmitter ACBP controls feeding and energy homeostasis via the melanocortin system
Published in The Journal of clinical investigation (01-06-2019)“…Glial cells have emerged as key players in the central control of energy balance and etiology of obesity. Astrocytes play a central role in neural…”
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Recent Advances in the Cellular and Molecular Mechanisms of Hypothalamic Neuronal Glucose Detection
Published in Frontiers in physiology (14-11-2017)“…The hypothalamus have been recognized for decades as one of the major brain centers for the control of energy homeostasis. This area contains specialized…”
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Insulin modulates emotional behavior through a serotonin-dependent mechanism
Published in Molecular psychiatry (01-06-2024)“…Type-2 Diabetes (T2D) is characterized by insulin resistance and accompanied by psychiatric comorbidities including major depressive disorders (MDD). Patients…”
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Apelin Treatment Increases Complete Fatty Acid Oxidation, Mitochondrial Oxidative Capacity, and Biogenesis in Muscle of Insulin-Resistant Mice
Published in Diabetes (New York, N.Y.) (01-02-2012)“…Both acute and chronic apelin treatment have been shown to improve insulin sensitivity in mice. However, the effects of apelin on fatty acid oxidation (FAO)…”
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Tissue Regeneration: The Dark Side of Opioids
Published in International journal of molecular sciences (08-07-2021)“…Opioids are regarded as among the most effective analgesic drugs and their use for the management of pain is considered standard of care. Despite their…”
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Postprandial Hyperglycemia Stimulates Neuroglial Plasticity in Hypothalamic POMC Neurons after a Balanced Meal
Published in Cell reports (Cambridge) (03-03-2020)“…Mechanistic studies in rodents evidenced synaptic remodeling in neuronal circuits that control food intake. However, the physiological relevance of this…”
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3D analysis of the whole subcutaneous adipose tissue reveals a complex spatial network of interconnected lobules with heterogeneous browning ability
Published in Scientific reports (30-04-2019)“…Adipose tissue, as the main energy storage organ and through its endocrine activity, is interconnected with all physiological functions. It plays a fundamental…”
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Adult stromal cells derived from human adipose tissue provoke pancreatic cancer cell death both in vitro and in vivo
Published in PloS one (17-07-2009)“…Normal tissue homeostasis is maintained by dynamic interactions between epithelial cells and their microenvironment. Disrupting this homeostasis can induce…”
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Physiology and biochemistry of type 2 diabetes: A tribute to Dr Alain Ktorza
Published in Biochimie (01-12-2017)Get full text
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Plasticity of human adipose lineage cells toward endothelial cells: Physiological and therapeutic perspectives
Published in Circulation (New York, N.Y.) (10-02-2004)“…Adipose tissue development and remodeling are closely associated with the growth of vascular network. We hypothesized that adipose tissue may contain…”
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Link Between Increased Satiety Gut Hormones and Reduced Food Reward After Gastric Bypass Surgery for Obesity
Published in The journal of clinical endocrinology and metabolism (01-02-2016)“…Context: Roux-en-Y gastric bypass (RYGB) surgery is an effective long-term intervention for weight loss maintenance, reducing appetite, and also food reward,…”
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Lactate fluxes mediated by the monocarboxylate transporter-1 are key determinants of the metabolic activity of beige adipocytes
Published in The Journal of biological chemistry (01-01-2021)“…Activation of energy-dissipating brown/beige adipocytes represents an attractive therapeutic strategy against metabolic disorders. While lactate is known to…”
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