Search Results - "Penglong, Tipparat"

BACH1 regulates erythrophagocytosis and iron‐recycling in β‐thalassemia by Penglong, Tipparat, Saensuwanna, Apisara, Pholngam, Nuttanan, Tansila, Natta, Buncherd, Hansuk, Srinoun, Kanitta

“…Macrophages play essential roles in erythrophagocytosis and iron recycling. β‐thalassemia is characterized by a genetic defect in hemoglobin synthesis, which…”
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The effects of Phorbol 12-myristate 13-acetate concentration on the expression of miR-155 and miR-125b and their macrophage function-related genes in the U937 cell line by Kuno, Suhaibee, Srinoun, Kanitta, Penglong, Tipparat

“…The phorbol 12-myristate 13-acetate (PMA)-induced U937 cell line has been widely used as an in vitro model for studying the functions of human macrophages…”
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miR-214 aggravates oxidative stress in thalassemic erythroid cells by targeting ATF4 by Penglong, Tipparat, Saensuwanna, Apisara, Jantapaso, Husanai, Phuwakanjana, Pongpon, Jearawiriyapaisarn, Natee, Paiboonsukwong, Kittiphong, Wanichsuwan, Worrawit, Srinoun, Kanitta

“…Oxidative damage to erythroid cells plays a key role in the pathogenesis of thalassemia. The oxidative stress in thalassemia is potentiated by heme, nonheme…”
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Molecular epidemiology and hematological profiles of hemoglobin variants in southern Thailand by Tepakhan, Wanicha, Kanjanaopas, Sataron, Sreworadechpisal, Korntip, Penglong, Tipparat, Sripornsawan, Pornpun, Wangchauy, Chaowanee, Nokkong, Chadaporn, Kongkan, Chulalak, Buathong, Saristha

“…Data on hemoglobin (Hb) variants in southern Thailand are lacking. This study aimed to reassess the frequency of Hb variants and the clinical aspects of…”
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Expression of microRNA-155 in thalassemic erythropoiesis by Penglong, Tipparat, Pholngam, Nuttanan, Tehyoh, Nasra, Tansila, Natta, Buncherd, Hansuk, Thanapongpichat, Supinya, Srinoun, Kanitta

“…Ineffective erythropoiesis (IE) is the primary cause of anemia and associated pathologies in -thalassemia. The characterization of IE is imbalance of erythroid…”
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The Effect of Polybrene on an aPTT-based Lupus Anticoagulant Test in the Plasma of Patients Receiving Unfractionated Heparin by Kongkan, Chulalak, Srinoun, Kanitta, Kaewmaneerat, Titirat, Penglong, Tipparat

“…Objective: Heparins can interfere with lupus anticoagulant (LA) testing, especially when the detection assays do not contain a heparin neutralizer. In this…”
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Expression of microRNA-451 in normal and thalassemic erythropoiesis by Svasti, Saovaros, Masaki, Shizuka, Penglong, Tipparat, Abe, Yasunobu, Winichagoon, Pranee, Fucharoen, Suthat, Umemura, Tsukuru

“…MicroRNAs (miRNAs) are negative regulators of gene expression that play an important role in hematopoiesis. Thalassemia, a defective globin synthesis leading…”
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The LXCXE Retinoblastoma Protein-Binding Motif of FOG-2 Regulates Adipogenesis by Goupille, Olivier, Penglong, Tipparat, Kadri, Zahra, Granger-Locatelli, Marine, Denis, Raphaël, Luquet, Serge, Badoual, Cécile, Fucharoen, Suthat, Maouche-Chrétien, Leila, Leboulch, Philippe, Chrétien, Stany

“…GATA transcription factors and their FOG cofactors play a key role in tissue-specific development and differentiation, from worms to humans. Mammals have six…”
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Clinical severity of β-thalassaemia/Hb E disease is associated with differential activities of the calpain-calpastatin proteolytic system by Sukati, Suriyan, Svasti, Saovaros, Stifanese, Roberto, Averna, Monica, Panutdaporn, Nantika, Penglong, Tipparat, Melloni, Edon, Fucharoen, Suthat, Katzenmeier, Gerd

“…Earlier observations in the literature suggest that proteolytic degradation of excess unmatched α-globin chains reduces their accumulation and precipitation in…”
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Reduced ADAMTS13 activity and high D-dimer levels are associated with thrombosis in patients with systemic lupus erythematosus by Penglong, Tipparat, Boontanvansom, Anuchit, Viboonjuntra, Pongtep, Siripaitoon, Boonjing

“…Patients with systemic lupus erythematosus (SLE) have an increased risk of vascular thrombosis compared to the general population. Therefore, biomarkers for…”
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Upregulation of miR-214 Mediates Oxidative Stress in Hb H Disease via Targeting of ATF4 by Saensuwanna, Apisara, Penglong, Tipparat, Srinoun, Kanitta

“…Thalassemia is a genetic disorder, occurring because of an imbalance in the globin chain production. Oxidative stress in erythroid cells of thalassemia is…”
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Anemia Severity in β-Thalassemia Correlates with Elevated Levels of microRNA-125b in Activated Phagocytic Monocytes by Kuno, Suhaibee, Penglong, Tipparat, Srinoun, Kanitta

“…β-Thalassemia (β-thal), is an inherited blood disorder caused by reduced or absent synthesis of β-globin chains leading to imbalance of globin chain synthesis…”
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Erythropoietin and IGF-1 signaling synchronize cell proliferation and maturation during erythropoiesis by Kadri, Zahra, Lefevre, Carine, Goupille, Olivier, Penglong, Tipparat, Granger-Locatelli, Marine, Fucharoen, Suthat, Maouche-Chretien, Leila, Leboulch, Philippe, Chretien, Stany

“…Tight coordination of cell proliferation and differentiation is central to red blood cell formation. Erythropoietin controls the proliferation and survival of…”
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MiR-144 Regulates Hemoglobin Expression in Human Erythroid Cell Line by PENGLONG, Tipparat, SAENSUWANNA, Apisara, KOCHAROENWAT, Jitpanu, BOORINTARAGOT, Wittawat, FUPONGSIRIPHAN, Suppanut, SRINOUN, Kanitta

“…The regulation of globin gene expression is significantly important to understand the pathogenesis of globin gene disorders. Recent findings have shown that…”
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Inhibition of the acetyl lysine-binding pocket of bromodomain and extraterminal domain proteins interferes with adipogenesis by Goupille, Olivier, Penglong, Tipparat, Kadri, Zahra, Granger-Locatelli, Marine, Fucharoen, Suthat, Maouche-Chrétien, Leila, Prost, Stéphane, Leboulch, Philippe, Chrétien, Stany

“…The bromodomain and extraterminal (BET) domain family proteins are epigenetic modulators involved in the reading of acetylated lysine residues. The first BET…”
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Clinical Severity of [beta]-thalassaemia/Hb E Disease Is Associated with Differential Activities of the Calpain-Calpastatin Proteolytic System by Sukati, Suriyan, Svasti, Saovaros, Stifanese, Roberto, Averna, Monica, Panutdaporn, Nantika, Penglong, Tipparat, Melloni, Edon, Fucharoen, Suthat, Katzenmeier, Gerd

“…Earlier observations in the literature suggest that proteolytic degradation of excess unmatched [alpha]-globin chains reduces their accumulation and…”
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BET bromodomain inhibition rescues erythropoietin differentiation of human erythroleukemia cell line UT7 by Goupille, Olivier, Penglong, Tipparat, Lefèvre, Carine, Granger, Marine, Kadri, Zahra, Fucharoen, Suthat, Maouche-Chrétien, Leila, Leboulch, Philippe, Chrétien, Stany

“…► UT7 erythroleukemia cells are known to be refractory to differentiate. ► Brief JQ1 treatment initiates the first steps of erythroid differentiation program…”
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