Search Results - "Peng, Yunru"
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Pharmacokinetics and tissue distribution study of caudatin in normal and diethylnitrosamine-induced hepatocellular carcinoma model rats
Published in Molecules (Basel, Switzerland) (05-03-2015)“…Caudatin is a potential antitumor agent isolated from the traditional Chinese medicine "baishouwu", which was the root tuber of Cynanchum auriculatum Royle ex…”
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2
Salidroside, A Natural Antioxidant, Improves β-Cell Survival and Function via Activating AMPK Pathway
Published in Frontiers in pharmacology (18-10-2017)“…The enhanced oxidative stress contributes to progression of type 2 diabetes mellitus (T2DM) and induces β-cell failure. Salidroside is a natural antioxidant…”
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3
Sub-acute toxicity of licorice-sargassum extract in Sprague-Dawley rats: biochemical, histopathological, and pharmacokinetic studies
Published in Chinese medical journal (05-04-2022)“…[2,3] However, the classic recipe “Hai-Zao-Yu-Hu-Tang,” (containing licorice and sargassum) is currently used, though the safety profile of this medication has…”
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4
Total C-21 Steroidal Glycosides From Baishouwu Ameliorate Hepatic and Renal Fibrosis by Regulating IL-1β/MyD88 Inflammation Signaling
Published in Frontiers in pharmacology (26-10-2021)“…Fibrosis is a worldwide public health problem, which typically results from chronic diseases and often leads to organ malfunction. Chronic inflammation has…”
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5
Resonance algorithm: an intuitive algorithm to find all shortest paths between two nodes
Published in Complex & intelligent systems (01-08-2023)“…The shortest path problem (SPP) is a classic problem and appears in a wide range of applications. Although a variety of algorithms already exist, new advances…”
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Characterization of Collagen Peptides in Elaphuri Davidiani Cornu Aqueous Extract with Proliferative Activity on Osteoblasts Using Nano-Liquid Chromatography in Tandem with Orbitrap Mass Spectrometry
Published in Molecules (Basel, Switzerland) (01-01-2017)“…First documented in (about 200 B.C.-200 A.D.), (EDC) has been recorded for its effects in strengthening bones and balancing other aspects of overall health for…”
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Metabolism of tanshinone IIA, cryptotanshinone and tanshinone I from Radix Salvia miltiorrhiza in zebrafish
Published in Molecules (Basel, Switzerland) (18-07-2012)“…The study aimed to investigate the potential of zebrafish in imitating mammal phase I metabolism of natural compounds. Three diterpenoid quinones from Radix…”
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Metabolism study of notoginsenoside R1, ginsenoside Rg1 and ginsenoside Rb1 of radix Panax notoginseng in zebrafish
Published in Molecules (Basel, Switzerland) (05-08-2011)“…Zebrafish, a common model organism for studies of vertebrate development and gene function, has been used in pharmaceutical research as a new and powerful tool…”
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9
Two new cytotoxic pregnane glycosides from Cynanchum auriculatum
Published in Planta medica (01-04-2008)“…Two new pregnane glycosides, kidjoranin 3- O- alpha-diginopyranosyl-(1-->4)- beta-cymaropyranoside (1) and kidjoranin 3-O-beta-digitoxopyranoside (2), together…”
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Mechanism of herb pair containing Astragali Radix and Spatholobi Caulis in the treatment of myelosuppression based on network pharmacology and experimental investigation
Published in Journal of ethnopharmacology (30-01-2024)“…The Astragali Radix and Spatholobi Caulis herb pair (ARSC) is one of the most commonly used herbal combinations for bone marrow suppression. According to…”
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11
Nanoemulsion delivery system of tea polyphenols enhanced the bioavailability of catechins in rats
Published in Food chemistry (01-03-2018)“…•TP nanoemulsion with particle size about 100nm was prepared.•TP nanoemulsion is stable during 20days’ storage.•Nanoemulsion improved the oral bioavailability…”
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12
Determination of caudatin-2,6-dideoxy-3-O-methy-β-d-cymaropyranoside in rat plasma using liquid chromatography-tandem mass spectrometry
Published in Biomedical chromatography (01-06-2008)“…A selective, sensitive and rapid liquid chromatography–tandem mass spectrometry method has been developed for the determination of…”
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13
Puerarin Protects Pancreatic β-Cells in Obese Diabetic Mice via Activation of GLP-1R Signaling
Published in Molecular endocrinology (Baltimore, Md.) (01-03-2016)“…Diabetes is characterized by a loss and dysfunction of the β-cell. Glucagon-like peptide 1 receptor (GLP-1R) signaling plays an important role in β-cell…”
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14
Diosmetin‐7‐O‐β‐D‐glucopyranoside suppresses endothelial–mesenchymal transformation through endoplasmic reticulum stress in cardiac fibrosis
Published in Clinical and experimental pharmacology & physiology (01-10-2023)“…Diosmetin‐7‐O‐β‐D‐glucopyranoside (Diosmetin‐7‐O‐glucoside) is a natural flavonoid glycoside known to have a therapeutic application for cardiovascular…”
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15
Toll-like receptor 4 signaling pathway mediates both liver and kidney injuries in mice with hepatorenal syndrome
Published in American journal of physiology: Gastrointestinal and liver physiology (01-11-2022)“…Hepatorenal syndrome (HRS) is a complication of cirrhosis with high morbidity and mortality. Nevertheless, the underlying mechanism involving how kidney injury…”
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Total C-21 steroidal glycosides, isolated from the root tuber of Cynanchum auriculatum Royle ex Wight, attenuate hydrogen peroxide-induced oxidative injury and inflammation in L02 cells
Published in International journal of molecular medicine (01-12-2018)“…Oxidative stress plays an important role in the pathology of liver disorders. Total C‑21 steroidal glycosides (TCSGs), isolated from the root tuber of…”
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Metabolic profiling of the hepatotoxicity and nephrotoxicity of Ginkgolic acids in rats using ultra-performance liquid chromatography-high-definition mass spectrometry
Published in Chemico-biological interactions (01-08-2017)“…Ginkgolic acids (GAs) are thought to be the potentially hazardous constituents corresponding to the toxic side effects of Ginkgo products. In this study,…”
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18
The “weaken-fill-repair” model for cell budding: Linking cell wall biosynthesis with mechanics
Published in iScience (18-10-2024)“…The interplay between cellular mechanics and biochemical processes in the cell cycle is not well understood. We propose a quantitative model of cell budding in…”
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Liposome encapsulation attenuated venenum bufonis induced vascular irritation in rabbit ear vein via regulating TLR/MAPK/NF-κB pathway
Published in RSC advances (01-01-2017)“…Delisheng injection (DLS), composed of venenum bufonis (VB), Chinese blister beetle (CB), red ginseng (RG) and Astragalus membranaceus (AM), is a Chinese…”
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20
Puerarin Protects Pancreatic [beta]-Cells in Obese Diabetic Mice via Activation of GLP-1R Signaling
Published in Molecular endocrinology (Baltimore, Md.) (01-03-2016)“…Diabetes is characterized by a loss and dysfunction of the [beta]-cell. Glucagon-like peptide 1 receptor (GLP-1R) signaling plays an important role in…”
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