Search Results - "Peng, Xiujuan"
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Quantification of M13 and T7 bacteriophages by TaqMan and SYBR green qPCR
Published in Journal of virological methods (01-02-2018)“…•SYBR Green and TaqMan qPCR were developed to quantify T7 and M13 phage.•SYBR Green qPCR sensitively detects selected phage from biopanning.•QPCR methods have…”
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Peptides as drug delivery vehicles across biological barriers
Published in Journal of pharmaceutical investigation (2018)“…Peptides are small biological molecules that are attractive in drug delivery and materials engineering for applications including therapeutics, molecular…”
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Identification of quality markers of Yuanhu Zhitong tablets based on integrative pharmacology and data mining
Published in Phytomedicine (Stuttgart) (15-05-2018)“…The quality evaluation of traditional Chinese medicine (TCM) formulations is needed to guarantee the safety and efficacy. In our laboratory, we established…”
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5-Azacytidine induces cardiac differentiation of human umbilical cord-derived mesenchymal stem cells by activating extracellular regulated kinase
Published in Stem cells and development (01-01-2012)“…5-Azacytidine (5-Aza) induces differentiation of mesenchymal stem cells (MSCs) into cardiomyocytes. However, the underlying mechanisms are not well understood…”
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Targeting NOX4 disrupts the resistance of papillary thyroid carcinoma to chemotherapeutic drugs and lenvatinib
Published in Cell death discovery (08-04-2022)“…Advanced differentiated thyroid cancer cells are subjected to extreme nutritional starvation which contributes to develop resistance to treatments; however,…”
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Deficiency of Multidrug and Toxin Extrusion 1 Enhances Renal Accumulation of Paraquat and Deteriorates Kidney Injury in Mice
Published in Molecular pharmaceutics (05-12-2011)“…Multidrug and toxin extrusion 1 (MATE1/solute carrier 47A1) mediates cellular transport of a variety of structurally diverse compounds. Paraquat (PQ), which…”
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Metabolome and transcriptome analyses identify the characteristics and expression of related saponins of the three genealogical plants of bead ginseng
Published in PeerJ (San Francisco, CA) (01-09-2023)“…Objective The classification and clinical usage of the different species of bead ginseng are often confused. Therefore, we conducted an integrated metabolomics…”
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Role of NLRP3 inflammasome activation in HCC cell progression
Published in Heliyon (01-09-2023)“…Hepatocellular carcinoma (HCC) is a globally prevalent and fatal malignancy worldwide, and identifying therapeutic strategies is time-consuming. Numerous…”
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Contribution of organic cation transporter 3 to cisplatin cytotoxicity in human cervical cancer cells
Published in Journal of pharmaceutical sciences (01-01-2012)“…This study was conducted to investigate whether drug transporters play a role in determination of cisplatin resistance in cervical cancer cells. The transcript…”
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Development and validation of a LC–MS/MS method for the determination of clebopride and its application to a pharmacokinetics study in healthy Chinese volunteers
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-08-2010)“…A sensitive and specific liquid chromatography–electrospray ionization-mass spectrometry (LC–ESI-MS/MS) method has been developed and validated for the…”
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Brain-Penetrating Peptide Shuttles across the Blood–Brain Barrier and Extracellular-like Space
Published in Bioconjugate chemistry (20-12-2023)“…Systemic delivery of therapeutics into the brain is greatly impaired by multiple biological barriersthe blood–brain barrier (BBB) and the extracellular matrix…”
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12
Manufacturing and ambient stability of shelf freeze dried bacteriophage powder formulations
Published in International journal of pharmaceutics (05-05-2018)“…[Display omitted] The severity of multidrug resistance to antibiotics has urged development of alternative treatment approaches, including bacteriophage…”
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13
Targeting mitochondrial dysfunctions in pancreatic cancer evokes new therapeutic opportunities
Published in Critical reviews in oncology/hematology (01-12-2022)“…Pancreatic cancer (PC) is a highly devastating neoplasm due to its irrepressible characteristics and propensity to override the available treatment strategies…”
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14
Application and Development Prospect of Nanoscale Iron Based Metal-Organic Frameworks in Biomedicine
Published in International journal of nanomedicine (01-09-2023)“…Metal-organic frameworks (MOFs) are coordination polymers that comprise metal ions/clusters and organic ligands. MOFs have been extensively employed in…”
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15
Yangzheng mixture reversed EMT against hepatocellular carcinoma metastasis via NF-κB/NLRP3/β-catenin pathway
Published in Toxicon (Oxford) (06-11-2024)“…Yangzheng mixture has been used as an adjuvant tumor therapy as a traditional Chinese medicine in clinical. However, less is known about the activity of…”
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Albendazole exerts an anti-hepatocellular carcinoma effect through a WWOX-dependent pathway
Published in Life sciences (1973) (01-12-2022)Get full text
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Controlled loading of albumin-drug conjugates ex vivo for enhanced drug delivery and antitumor efficacy
Published in Journal of controlled release (10-12-2020)“…To harness the intrinsic transport properties of albumin yet improve the therapeutic index of current in situ albumin-binding prodrugs, we developed…”
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Peptides as surface coatings of nanoparticles that penetrate human cystic fibrosis sputum and uniformly distribute in vivo following pulmonary delivery
Published in Journal of controlled release (10-06-2020)“…Therapeutic delivery of drug and gene delivery systems have to traverse multiple biological barriers to achieve efficacy. Mucosal administration, such as…”
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Shuanghua decoction exerts anticancer activity by activating NLRP3 inflammasome via ROS and inhibiting NF-κB signaling in hepatocellular carcinoma cells
Published in Phytomedicine (Stuttgart) (01-08-2022)“…•The traditional folk recipe “Shuanghua decoction” (SHD) and its main ingredients oldenlandia and OP (oldenlandia: prunella spike = 2.5:1) exhibited inhibition…”
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Identification and analysis of anti‐tumor effective substances in Yangzheng Mixture
Published in Biomedical chromatography (01-09-2023)“…Yangzheng Mixture is a traditional Chinese medicine used in clinical practice as an adjuvant therapy for tumors. However, little is known about its active…”
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