Search Results - "Peng, Pei‐Hua"
-
1
METTL4-mediated nuclear N6-deoxyadenosine methylation promotes metastasis through activating multiple metastasis-inducing targets
Published in Genome Biology (02-12-2022)“…DNA N6-methyldeoxyadenosine (6mA) is rarely present in mammalian cells and its nuclear role remains elusive. Here we show that hypoxia induces nuclear 6mA…”
Get full text
Journal Article -
2
Identification and validation of a miRNA-based prognostic signature for cervical cancer through an integrated bioinformatics approach
Published in Scientific reports (17-12-2020)“…Cervical cancer is the fourth most common cancer in women worldwide. Increasing evidence has shown that miRNAs are related to the progression of cervical…”
Get full text
Journal Article -
3
The role of hypoxia-induced long noncoding RNAs (lncRNAs) in tumorigenesis and metastasis
Published in Biomedical Journal (01-10-2021)“…Long noncoding RNAs (lncRNAs) are noncoding RNAs with length greater than 200 nt. The biological roles and mechanisms mediated by lncRNAs have been extensively…”
Get full text
Journal Article -
4
Integration of the cancer cell secretome and transcriptome reveals potential noninvasive diagnostic markers for bladder cancer
Published in Proteomics. Clinical applications (01-07-2024)“…Purpose Bladder cancer (BLCA) is a major cancer of the genitourinary system. Although cystoscopy is the standard protocol for diagnosing BLCA clinically, this…”
Get full text
Journal Article -
5
RP11‐367G18.1 V2 enhances clear cell renal cell carcinoma progression via induction of epithelial–mesenchymal transition
Published in Cancer medicine (Malden, MA) (01-04-2023)“…Purpose Metastasis is the end stage of renal cell carcinoma (RCC), and clear cell renal cell carcinoma (ccRCC) is the most common malignant subtype. The…”
Get full text
Journal Article -
6
Interplay between lncRNA RP11-367G18.1 variant 2 and YY1 plays a vital role in hypoxia-mediated gene expression and tumorigenesis
Published in Cancer cell international (08-11-2023)“…Abstract Background The hypoxia-responsive long non-coding RNA, RP11-367G18.1 , has recently been reported to induce histone 4 lysine 16 acetylation (H4K16Ac)…”
Get full text
Journal Article -
7
Chromatin accessibility analysis identifies GSTM1 as a prognostic marker in human glioblastoma patients
Published in Clinical epigenetics (01-12-2021)“…Glioblastoma (GBM) is a malignant human brain tumor that has an extremely poor prognosis. Classic mutations such as IDH (isocitrate dehydrogenase) mutations,…”
Get full text
Journal Article -
8
Scutellarin Reduces Cerebral Ischemia Reperfusion Injury Involving in Vascular Endothelium Protection and PKG Signal
Published in Natural products and bioprospecting (01-12-2021)“…Flavonoid glycoside scutellarin (SCU) has been widely applied in the treatment of cerebral ischemic diseases in China. In this article, we conducted research…”
Get full text
Journal Article -
9
Using bioinformatics approaches to identify survival-related oncomiRs as potential targets of miRNA-based treatments for lung adenocarcinoma
Published in Computational and structural biotechnology journal (01-01-2022)“…[Display omitted] Lung cancer is a major cause of cancer-associated deaths worldwide, and lung adenocarcinoma (LUAD) is the most common lung cancer subtype…”
Get full text
Journal Article -
10
Identification of candidate nasopharyngeal carcinoma serum biomarkers by cancer cell secretome and tissue transcriptome analysis: Potential usage of cystatin A for predicting nodal stage and poor prognosis
Published in Proteomics (Weinheim) (01-07-2010)“…Nasopharyngeal carcinoma (NPC) is usually diagnosed at advanced clinical stages, resulting in poor outcomes. To discover serum biomarkers for improved NPC…”
Get full text
Journal Article -
11
Hypoxia-induced lncRNA RP11-390F4.3 promotes epithelial-mesenchymal transition (EMT) and metastasis through upregulating EMT regulators
Published in Cancer letters (28-07-2020)“…Hypoxia-induced long noncoding RNAs (lncRNAs) have been shown to induce tumor metastasis. However, lncRNAs that are regulated by hypoxia/HIF-1α and…”
Get full text
Journal Article -
12
Identification of potential serum markers for nasopharyngeal carcinoma from a xenografted mouse model using Cy-dye labeling combined with three-dimensional fractionation
Published in Proteomics (Weinheim) (01-09-2008)“…Nasopharyngeal carcinoma (NPC), one of the most common cancers in Southeast Asia, is commonly diagnosed late due to its deep location and vague symptoms. To…”
Get full text
Journal Article -
13
Epigenetic regulation of asymmetric cell division by the LIBR-BRD4 axis
Published in Nucleic acids research (11-01-2024)“…Abstract Asymmetric cell division (ACD) is a mechanism used by stem cells to maintain the number of progeny. However, the epigenetic mechanisms regulating ACD…”
Get full text
Journal Article -
14
PLK1 and its substrate MISP facilitate intrahepatic cholangiocarcinoma progression by promoting lymphatic invasion and impairing E-cadherin adherens junctions
Published in Cancer gene therapy (01-02-2024)“…Intrahepatic cholangiocarcinoma (iCCA) is a subtype of CCA and has a high mortality rate and a relatively poor prognosis. However, studies focusing on…”
Get full text
Journal Article -
15
Targeting interleukin-17 receptor B enhances gemcitabine sensitivity through downregulation of mucins in pancreatic cancer
Published in Scientific reports (20-10-2020)“…Pancreatic cancer is the fourth leading cause of death worldwide due to its poorest prognoses with a 7% 5-year survival rate. Eighty percent of pancreatic…”
Get full text
Journal Article -
16
Secretome Profiling of Primary Cells Reveals That THBS2 Is a Salivary Biomarker of Oral Cavity Squamous Cell Carcinoma
Published in Journal of proteome research (07-11-2014)“…Oral cavity squamous cell carcinoma (OSCC), which is a leading cause of cancer-related death worldwide, is frequently associated with poor prognosis and…”
Get full text
Journal Article -
17
Genomic and cDNA Cloning, Characterization of Delonix regia Trypsin Inhibitor (DrTI) Gene, and Expression of DrTI in Escherichia coli
Published in Bioscience, biotechnology, and biochemistry (01-01-2007)“…Degenerate primers were designed based on all possible sequences of the N-terminal and C-terminal regions of Delonix regia trypsin inhibitor (DrTI). Five…”
Get full text
Journal Article -
18
Identification of secretory gelsolin as a plasma biomarker associated with distant organ metastasis of colorectal cancer
Published in Journal of molecular medicine (Berlin, Germany) (01-02-2012)“…Colorectal cancer (CRC) is one of the most common cancers worldwide. More than half of all CRC patients will develop metastases, which represents the major…”
Get full text
Journal Article -
19
Quantitative plasma proteome analysis reveals aberrant level of blood coagulation-related proteins in nasopharyngeal carcinoma
Published in Journal of proteomics (01-05-2011)“…Nasopharyngeal carcinoma (NPC), one of the most common cancers in Southeast Asia, is not easily diagnosed until advanced stages. To discover potential…”
Get full text
Journal Article -
20
Liquid-liquid phase separation (LLPS) in cellular physiology and tumor biology
Published in American journal of cancer research (01-01-2021)“…Liquid-liquid phase separation (LLPS) has emerged as a mechanism that has been used to explain the formation of known organelles (e.g. nucleoli, promyelocytic…”
Get full text
Journal Article