Search Results - "Peng, Nias Y G"
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Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes
Published in Nature communications (05-05-2020)“…Flaviviruses, including Zika virus (ZIKV), utilise host mRNA degradation machinery to produce subgenomic flaviviral RNA (sfRNA). In mammalian hosts, this…”
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The distinguishing NS5-M114V mutation in American Zika virus isolates has negligible impacts on virus replication and transmission potential
Published in PLoS neglected tropical diseases (01-05-2022)“…During 2015-2016, outbreaks of Zika virus (ZIKV) occurred in Southeast Asia and the Americas. Most ZIKV infections in humans are asymptomatic, while clinical…”
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Utilizing Molecular Epidemiology and Citizen Science for the Surveillance of Lagoviruses in Australia
Published in Viruses (29-11-2023)“…Australia has multiple lagoviruses with differing pathogenicity. The circulation of these viruses was traditionally determined through opportunistic sampling…”
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Residue K28 of Zika Virus NS5 Protein Is Implicated in Virus Replication and Antagonism of STAT2
Published in Microorganisms (Basel) (01-04-2024)“…The identification of four potential nonstructural 5 (NS5) residues-K28, K45, V335, and S749-that share the same amino acid preference in STAT2-interacting…”
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An Optimized High-Throughput Immuno-Plaque Assay for SARS-CoV-2
Published in Frontiers in microbiology (12-02-2021)“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been identified as the causative agent of coronavirus disease 2019 and is capable of…”
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Determinants of Zika virus host tropism uncovered by deep mutational scanning
Published in Nature microbiology (01-05-2019)“…Arboviruses cycle between, and replicate in, both invertebrate and vertebrate hosts, which for Zika virus (ZIKV) involves Aedes mosquitoes and primates 1 . The…”
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SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein
Published in Molecular psychiatry (01-07-2023)“…Coronavirus disease-2019 (COVID-19) is primarily a respiratory disease, however, an increasing number of reports indicate that SARS-CoV-2 infection can also…”
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Hepatobiliary organoids derived from leporids support the replication of hepatotropic lagoviruses
Published in Journal of general virology (01-01-2023)“…The genus Lagovirus of the family Caliciviridae contains some of the most virulent vertebrate viruses known. Lagoviruses infect leporids, such as rabbits,…”
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CCR2 Plays a Protective Role in Rocio Virus-Induced Encephalitis by Promoting Macrophage Infiltration Into the Brain
Published in The Journal of infectious diseases (24-05-2019)“…Rocio virus (ROCV) is a highly neuropathogenic mosquito-transmitted flavivirus responsible for an unprecedented outbreak of human encephalitis during 1975-1976…”
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A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses
Published in Nature communications (08-06-2021)“…The current COVID-19 pandemic is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We demonstrate that despite the large size of the…”
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