Search Results - "Peng, Nias"

Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes by Slonchak, Andrii, Hugo, Leon E., Freney, Morgan E., Hall-Mendelin, Sonja, Amarilla, Alberto A., Torres, Francisco J., Setoh, Yin Xiang, Peng, Nias Y. G., Sng, Julian D. J., Hall, Roy A., van den Hurk, Andrew F., Devine, Gregor J., Khromykh, Alexander A.

“…Flaviviruses, including Zika virus (ZIKV), utilise host mRNA degradation machinery to produce subgenomic flaviviral RNA (sfRNA). In mammalian hosts, this…”
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SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein by Albornoz, Eduardo A., Amarilla, Alberto A., Modhiran, Naphak, Parker, Sandra, Li, Xaria X., Wijesundara, Danushka K., Aguado, Julio, Zamora, Adriana Pliego, McMillan, Christopher L. D., Liang, Benjamin, Peng, Nias Y. G., Sng, Julian D. J., Saima, Fatema Tuj, Fung, Jenny N., Lee, John D., Paramitha, Devina, Parry, Rhys, Avumegah, Michael S., Isaacs, Ariel, Lo, Martin W., Miranda-Chacon, Zaray, Bradshaw, Daniella, Salinas-Rebolledo, Constanza, Rajapakse, Niwanthi W., Wolvetang, Ernst J., Munro, Trent P., Rojas-Fernandez, Alejandro, Young, Paul R., Stacey, Katryn J., Khromykh, Alexander A., Chappell, Keith J., Watterson, Daniel, Woodruff, Trent M.

“…Coronavirus disease-2019 (COVID-19) is primarily a respiratory disease, however, an increasing number of reports indicate that SARS-CoV-2 infection can also…”
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Utilizing Molecular Epidemiology and Citizen Science for the Surveillance of Lagoviruses in Australia by Peng, Nias Y G, Hall, Robyn N, Huang, Nina, West, Peter, Cox, Tarnya E, Mahar, Jackie E, Mason, Hugh, Campbell, Susan, O'Connor, Tiffany, Read, Andrew J, Patel, Kandarp K, Taggart, Patrick L, Smith, Ina L, Strive, Tanja, Jenckel, Maria

“…Australia has multiple lagoviruses with differing pathogenicity. The circulation of these viruses was traditionally determined through opportunistic sampling…”
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The distinguishing NS5-M114V mutation in American Zika virus isolates has negligible impacts on virus replication and transmission potential by Peng, Nias Y G, Amarilla, Alberto A, Hugo, Leon E, Modhiran, Naphak, Sng, Julian D J, Slonchak, Andrii, Watterson, Daniel, Setoh, Yin Xiang, Khromykh, Alexander A

“…During 2015-2016, outbreaks of Zika virus (ZIKV) occurred in Southeast Asia and the Americas. Most ZIKV infections in humans are asymptomatic, while clinical…”
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Hepatobiliary organoids derived from leporids support the replication of hepatotropic lagoviruses by Kardia, Egi, Fakhri, Omid, Pavy, Megan, Mason, Hugh, Huang, Nina, Smertina, Elena, Jenckel, Maria, Peng, Nias Y. G., Estes, Mary K., Strive, Tanja, Frese, Michael, Smith, Ina, Hall, Robyn N.

“…The genus Lagovirus of the family Caliciviridae contains some of the most virulent vertebrate viruses known. Lagoviruses infect leporids, such as rabbits,…”
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An Optimized High-Throughput Immuno-Plaque Assay for SARS-CoV-2 by Amarilla, Alberto A, Modhiran, Naphak, Setoh, Yin Xiang, Peng, Nias Y G, Sng, Julian D J, Liang, Benjamin, McMillan, Christopher L D, Freney, Morgan E, Cheung, Stacey T M, Chappell, Keith J, Khromykh, Alexander A, Young, Paul R, Watterson, Daniel

“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been identified as the causative agent of coronavirus disease 2019 and is capable of…”
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Residue K28 of Zika Virus NS5 Protein Is Implicated in Virus Replication and Antagonism of STAT2 by Peng, Nias Y G, Sng, Julian D J, Setoh, Yin Xiang, Khromykh, Alexander A

“…The identification of four potential nonstructural 5 (NS5) residues-K28, K45, V335, and S749-that share the same amino acid preference in STAT2-interacting…”
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Determinants of Zika virus host tropism uncovered by deep mutational scanning by Setoh, Yin Xiang, Amarilla, Alberto A., Peng, Nias Y. G., Griffiths, Rebecca E., Carrera, Julio, Freney, Morgan E., Nakayama, Eri, Ogawa, Shinya, Watterson, Daniel, Modhiran, Naphak, Nanyonga, Faith Elizabeth, Torres, Francisco J., Slonchak, Andrii, Periasamy, Parthiban, Prow, Natalie A., Tang, Bing, Harrison, Jessica, Hobson-Peters, Jody, Cuddihy, Thom, Cooper-White, Justin, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Wolvetang, Ernst, Bloom, Jesse D., Suhrbier, Andreas, Khromykh, Alexander A.

“…Arboviruses cycle between, and replicate in, both invertebrate and vertebrate hosts, which for Zika virus (ZIKV) involves Aedes mosquitoes and primates 1 . The…”
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Fetal Brain Infection Is Not a Unique Characteristic of Brazilian Zika Viruses by Setoh, Yin Xiang, Peng, Nias Y, Nakayama, Eri, Amarilla, Alberto A, Prow, Natalie A, Suhrbier, Andreas, Khromykh, Alexander A

“…The recent emergence of Zika virus (ZIKV) in Brazil was associated with an increased number of fetal brain infections that resulted in a spectrum of congenital…”
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Chimeric viruses between Rocio and West Nile: the role for Rocio prM-E proteins in virulence and inhibition of interferon-α/β signaling by Amarilla, Alberto A., Setoh, Yin X., Periasamy, Parthiban, Peng, Nias Y., Pali, Gabor, Figueiredo, Luiz T., Khromykh, Alexander A., Aquino, Victor H.

“…Mosquito-transmitted flavivirus Rocio (ROCV) was responsible for an outbreak of encephalitis in the Ribeira Valley, located in the south coast of Sao Paulo…”
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CCR2 Plays a Protective Role in Rocio Virus-Induced Encephalitis by Promoting Macrophage Infiltration Into the Brain by Amarilla, Alberto A, Santos-Junior, Nilton Nascimento, Figueiredo, Mario Luis, Luiz, Joao Paulo Mesquita, Fumagalli, Marcilio Jorge, Colón, David F, Lippi, Veronica, Alfonso, Helda Liz, Lima-Junior, Djalma S, Trabuco, Amanda C, Spinieli, Richard L, Desidera, Amanda C, Leite-Panissi, Christie R A, Lauretti, Flávio, Mendoza, Silvia Elena Sánchez, Silva, Cleide Lúcia Araújo, Rego, Eduardo Magalhaes, Galvao-Lima, Leonardo J, Bassi, Gabriel S, Penharvel Martíns, Sandra L B, Manrique, Wilson Gomez, Alves-Filho, José Carlos, Cunha, Fernando Q, Peng, Nias Y G, Modhiran, Naphak, Setoh, Yin Xiang, Khromykh, Alexander A, Figueiredo, Luiz T M, Aquino, Victor H

“…Rocio virus (ROCV) is a highly neuropathogenic mosquito-transmitted flavivirus responsible for an unprecedented outbreak of human encephalitis during 1975-1976…”
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De Novo Generation and Characterization of New Zika Virus Isolate Using Sequence Data from a Microcephaly Case by Setoh, Yin Xiang, Prow, Natalie A, Peng, Nias, Hugo, Leon E, Devine, Gregor, Hazlewood, Jessamine E, Suhrbier, Andreas, Khromykh, Alexander A

“…Zika virus (ZIKV) has recently emerged and is the etiological agent of congenital Zika syndrome (CZS), a spectrum of congenital abnormalities arising from…”
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Helicase Domain of West Nile Virus NS3 Protein Plays a Role in Inhibition of Type I Interferon Signalling by Setoh, Yin Xiang, Periasamy, Parthiban, Peng, Nias Yong Gao, Amarilla, Alberto A, Slonchak, Andrii, Khromykh, Alexander A

“…West Nile virus (WNV) is a neurotropic flavivirus that can cause encephalitis in mammalian and avian hosts. In America, the virulent WNV strain (NY99) is…”
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Full genome sequence of Rocio virus reveal substantial variations from the prototype Rocio virus SPH 34675 sequence by Setoh, Yin Xiang, Amarilla, Alberto A., Peng, Nias Y., Slonchak, Andrii, Periasamy, Parthiban, Figueiredo, Luiz T. M., Aquino, Victor H., Khromykh, Alexander A.

“…Rocio virus (ROCV) is an arbovirus belonging to the genus Flavivirus , family Flaviviridae . We present an updated sequence of ROCV strain SPH 34675 (GenBank:…”
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A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses by Amarilla, Alberto A., Sng, Julian D. J., Parry, Rhys, Deerain, Joshua M., Potter, James R., Setoh, Yin Xiang, Rawle, Daniel J., Le, Thuy T., Modhiran, Naphak, Wang, Xiaohui, Peng, Nias Y. G., Torres, Francisco J., Pyke, Alyssa, Harrison, Jessica J., Freney, Morgan E., Liang, Benjamin, McMillan, Christopher L. D., Cheung, Stacey T. M., Guevara, Darwin J. Da Costa, Hardy, Joshua M., Bettington, Mark, Muller, David A., Coulibaly, Fasséli, Moore, Frederick, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Hobson-Peters, Jody, Suhrbier, Andreas, Watterson, Daniel, Khromykh, Alexander A.

“…The current COVID-19 pandemic is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We demonstrate that despite the large size of the…”
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Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis by Slonchak, Andrii, Wang, Xiaohui, Aguado, Julio, Sng, Julian D J, Chaggar, Harman, Freney, Morgan E, Yan, Kexin, Torres, Francisco J, Amarilla, Alberto A, Balea, Rickyle, Setoh, Yin Xiang, Peng, Nias, Watterson, Daniel, Wolvetang, Ernst, Suhrbier, Andreas, Khromykh, Alexander A

“…All flaviviruses, including Zika virus, produce noncoding subgenomic flaviviral RNA (sfRNA), which plays an important role in viral pathogenesis. However, the…”
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Zika Virus sfRNA Plays an Essential Role in the Infection of Insects and Mammals by Andrii Slonchak, Leon E. Hugo, Morgan Freney, Alberto A Amarilla, Sonja Hall-Mendelin, Kexin Yan, Francisco Torres, Yin Xiang Setoh, Nias Peng, Harman K Chaggar, Andrew Van Den Hurk, Ernst Wolvetang, Andreas Suhrbier, Gregor J. Devine, Alexander A Khromykh

“…Similar to other flaviviruses, Zika virus (ZIKV) produces abundant subgenomic flavivirus RNA (sfRNA) derived from the 3’ untranslated region. The molecular…”
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italic toggle="yes">De Novo /italic> Generation and Characterization of New Zika Virus Isolate Using Sequence Data from a Microcephaly Case by Yin Xiang Setoh, Natalie A. Prow, Nias Peng, Leon E. Hugo, Gregor Devine, Jessamine E. Hazlewood, Andreas Suhrbier, Alexander A. Khromykh

“…ABSTRACT Zika virus (ZIKV) has recently emerged and is the etiological agent of congenital Zika syndrome (CZS), a spectrum of congenital abnormalities arising…”
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Chimeric viruses between Rocio and West Nile: the role for Rocio prM-E proteins in virulence and inhibition of interferon-[alpha]/[beta] signaling by Amarilla, Alberto A, Setoh, Yin X, Periasamy, Parthiban, Peng, Nias Y, Pali, Gabor, Figueiredo, Luiz T, Khromykh, Alexander A, Aquino, Victor H

“…Mosquito-transmitted flavivirus Rocio (ROCV) was responsible for an outbreak of encephalitis in the Ribeira Valley, located in the south coast of Sao Paulo…”
Get full text