Search Results - "Peng, Katherine"
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Apolipoprotein E2 Expression Alters Endosomal Pathways in a Mouse Model With Increased Brain Exosome Levels During Aging
Published in Traffic (Copenhagen, Denmark) (01-05-2024)“…ABSTRACT The polymorphic APOE gene is the greatest genetic determinant of sporadic Alzheimer's disease risk: the APOE4 allele increases risk, while the APOE2…”
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2
Apolipoprotein E4 genotype compromises brain exosome production
Published in Brain (London, England : 1878) (01-01-2019)“…APOE4 is a genetic risk factor for ageing-related cognitive decline and Alzheimer's disease. Using human and mouse tissue, Peng et al. report that APOE4…”
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3
Apolipoprotein E4 causes early olfactory network abnormalities and short-term olfactory memory impairments
Published in Neuroscience (20-02-2017)“…Highlights • Olfactory deficits are shown in young, but not middle-aged, ApoE4 vs. ApoE3 mice. • Young ApoE4 vs. ApoE3 mice exhibit hyperactive LFP response to…”
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The Endosomal-Lysosomal Pathway Is Dysregulated by APOE4 Expression in Vivo
Published in Frontiers in neuroscience (12-12-2017)“…Possession of the ε4 allele of apolipoprotein E ( ) is the major genetic risk factor for late-onset Alzheimer's disease (AD). Although numerous hypotheses have…”
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Social regulation of immediate early gene induction in gonadotropin releasing-hormone 1 neurons and singing behavior in canaries (Serinus canaria)
Published in Physiology & behavior (01-11-2022)“…•Female presence reduced male singing rate, song duration and special syllables.•Canaries paired with a potential mate had a higher proportion of GnRH cells…”
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Trends in surgical complexity and treatment modalities utilized in the management of ovarian cancer in an era of neoadjuvant chemotherapy
Published in Gynecologic oncology (01-08-2019)“…To investigate the impact of the increased use of neoadjuvant chemotherapy on the complexity of cytoreductive surgeries for ovarian cancer. Using the National…”
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Brain apolipoprotein E levels in mice challenged by a Western diet increase in an allele-dependent manner
Published in Aging brain (01-01-2023)“…Human apolipoprotein E (APOE) is the greatest determinant of genetic risk for memory deficits and Alzheimer's disease (AD). While APOE4 drives memory loss and…”
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Evaluation of sentinel lymph node detection rates at increasing BMI
Published in Gynecologic oncology (01-08-2021)“…Sentinel lymph node (SLN) mapping has become the preferred method for surgical staging of endometrial cancer; however, previous studies on SLN mapping have not…”
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Recurrence Rates in Patients With Cervical Cancer Treated With Abdominal Versus Minimally Invasive Radical Hysterectomy: A Multi-Institutional Retrospective Review Study
Published in Journal of clinical oncology (01-04-2020)“…To compare the disease-free survival (DFS) between open and minimally invasive radical hysterectomies (RH) performed in academic medical institutions…”
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10
Speculum Lubrication and Patient Comfort: A Meta-Analysis of Randomized Controlled Trials
Published in Journal of lower genital tract disease (01-01-2017)“…The aim of the study was to examine the effect of water-based gel lubrication in decreasing discomfort during speculum examination. Searches of standard…”
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Dissociable effects of social context on song and doublecortin immunoreactivity in male canaries
Published in The European journal of neuroscience (01-09-2014)“…Variation in environmental factors such as day length and social context greatly affects reproductive behavior and the brain areas that regulate these…”
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Interrelationships between endosomal pathology and exosomal generation and release in neurodegenerative disorders
Published in Journal of extracellular vesicles (01-01-2018)“…Background: Dysfunction of the neuronal endosomal pathway is a characteristic of down syndrome (DS) and Alzheimer's disease (AD) and of carriers of the AD-risk…”
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Apolipoprotein E4 Mediates Endosomal-Exosomal Dysfunction and Regional Hyperactivity in the Brain
Published 2017“…The apolipoprotein E4 (ApoE4) allele, compared with the more common apolipoprotein E3 (ApoE3) allele, is the greatest genetic risk factor for sporadic…”
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Dissertation -
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Apolipoprotein E4 compromises brain exosome production and secretion
Published in Journal of extracellular vesicles (01-01-2018)“…Background: The apolipoprotein E (APOE) gene codes for the brain's primary cholesterol carrier protein. In both humans and humanized APOE mice the Alzheimer's…”
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Heterosexual risk of HIV infection in China: systematic review and meta-analysis
Published in Chinese medical journal (01-06-2011)“…Background Heterosexual sex has become the dominant transmission route in China. Recently studies reported high heterogeneity in heterosexual transmission risk…”
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