Search Results - "Peng, Junya"

Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration by Ma, Liang, Li, Ying, Peng, Junya, Wu, Danni, Zhao, Xiaoxin, Cui, Yitong, Chen, Lilian, Yan, Xiaojun, Du, Yanan, Yu, Li

“…Cells communicate with each other through secreting and releasing proteins and vesicles. Many cells can migrate. In this study, we report the discovery of…”
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Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma by Peng, Junya, Sun, Bao-Fa, Chen, Chuan-Yuan, Zhou, Jia-Yi, Chen, Yu-Sheng, Chen, Hao, Liu, Lulu, Huang, Dan, Jiang, Jialin, Cui, Guan-Shen, Yang, Ying, Wang, Wenze, Guo, Dan, Dai, Menghua, Guo, Junchao, Zhang, Taiping, Liao, Quan, Liu, Yi, Zhao, Yong-Liang, Han, Da-Li, Zhao, Yupei, Yang, Yun-Gui, Wu, Wenming

“…Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer featured with high intra-tumoral heterogeneity and poor prognosis. To…”
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Identification of markers for migrasome detection by Zhao, Xiaoxin, Lei, Yaxin, Zheng, Jiajia, Peng, Junya, Li, Ying, Yu, Li, Chen, Yang

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Termination of autophagy and reformation of lysosomes regulated by mTOR by Lenardo, Michael J, Yu, Li, McPhee, Christina K, Zheng, Lixin, Mardones, Gonzalo A, Rong, Yueguang, Peng, Junya, Mi, Na, Zhao, Ying, Liu, Zhihua, Wan, Fengyi, Hailey, Dale W, Oorschot, Viola, Klumperman, Judith, Baehrecke, Eric H

“…Autophagy is an evolutionarily conserved process by which cytoplasmic proteins and organelles are catabolized. During starvation, the protein TOR (target of…”
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Roles of Extracellular Vesicles in Metastatic Breast Cancer by Peng, Junya, Wang, Wenqian, Hua, Surong, Liu, Lulu

“…Cells can secrete extracellular vesicles (EVs) to communicate with neighboring or distant cells by EVs which are composed of a lipid bilayer containing…”
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Novel technologies in cfDNA analysis and potential utility in clinic by Li, Jie, Xu, Mengyue, Peng, Junya, Wang, Jingqiao, Zhao, Yupei, Wu, Wenming, Lan, Xun

“…The profiling of plasma cell-free DNA (cfDNA) is becoming a valuable tool rapidly for tumor diagnosis, monitoring and prognosis. Diverse plasma cfDNA…”
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Synthesis and Discovery Novel Anti-Cancer Stem Cells Compounds Derived from the Natural Triterpenoic Acids by Liu, Xinhua, Li, Benlong, Zhang, Zhen, Wei, Yujiao, Xu, Zhongxin, Qin, Shuanglin, Liu, Ning, Zhao, Rui, Peng, Junya, Yang, Guang, Qi, Min, Liu, Tongtong, Xie, Maodun, Liu, Shuangwei, Gao, Xian, Lu, Cheng, Zhu, Lijun, Long, Xinyu, Kang, Hong, Sun, Tao, Zhou, Honggang, Wei, Mingming, Yang, Guang, Yang, Cheng

“…Cancer stem cells (CSCs) have been reported to be involved in tumorigenesis, tumor recurrence, cancer invasion, metastasis, and drug-resistance. Therefore, the…”
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Author Correction: Identification of markers for migrasome detection by Zhao, Xiaoxin, Lei, Yaxin, Zheng, Jiajia, Peng, Junya, Li, Ying, Yu, Li, Chen, Yang

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Mutant Kras co-opts a proto-oncogenic enhancer network in inflammation-induced metaplastic progenitor cells to initiate pancreatic cancer by Li, Yong, He, Yi, Peng, Junya, Su, Zhendong, Li, Zeyao, Zhang, Bingjie, Ma, Jing, Zhuo, Meilian, Zou, Di, Liu, Xinde, Liu, Xinhong, Wang, Wenze, Huang, Dan, Xu, Mengyue, Wang, Jianbin, Deng, Haiteng, Xue, Jing, Xie, Wei, Lan, Xun, Chen, Mo, Zhao, Yupei, Wu, Wenming, David, Charles J

“…Kras-activating mutations display the highest incidence in pancreatic ductal adenocarcinoma. Pancreatic inflammation accelerates mutant Kras-driven…”
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Protocol to isolate human normal and neoplastic pancreatic cells for single-cell omic analyses by Chen, Hao, Peng, Junya, Liu, Lulu, Huang, Dan, Zhao, Yupei, Wu, Wenming

“…The high-throughput sequencing at single-cell resolution requires high-quality samples of inputted 100–10,000 cells with at least 80%–90% viability according…”
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Atg5 regulates late endosome and lysosome biogenesis by Peng, JunYa, Zhang, Ran, Cui, YiTong, Liu, HaoDong, Zhao, XiaoXin, Huang, Lei, Hu, MingXu, Yuan, XiaoXi, Ma, BenYu, Ma, XiaoWei, Takashi, Ueno, Masaaki, Komatsu, Liang, XingJie, Yu, Li

“…Autophagy is an evolutionarily conserved lysosome-based degradation process. Atg5 plays a very important role in autopha- gosome formation. Here we show that…”
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Pancreatic cancer-educated macrophages protect cancer cells from complement-dependent cytotoxicity by up-regulation of CD59 by Zhang, Ronghua, Liu, Qiaofei, Peng, Junya, Wang, Mengyi, Gao, Xiang, Liao, Quan, Zhao, Yupei

“…Tumor-associated macrophages (TAMs) are versatile immune cells that promote a variety of malignant behaviors of pancreatic cancer. CD59 is a GPI-anchored…”
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ABCD1 as a Novel Diagnostic Marker for Solid Pseudopapillary Neoplasm of the Pancreas by Liu, Ying-Ao, Liu, Yuanhao, Tu, Jiajuan, Shi, Yihong, Pang, Junyi, Huang, Qi, Wang, Xun, Lin, Zhixiang, Zhao, Yupei, Wang, Wenze, Peng, Junya, Wu, Wenming

“…The diagnosis of solid pseudopapillary neoplasm of the pancreas (SPN) can be challenging due to potential confusion with other pancreatic neoplasms,…”
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RESEARCH ON THE GUARANTEE MECHANISM OF HIGH-QUALITY DEVELOPMENT OF PRIMARY SCHOOLS BASED ON THE BACKGROUND OF EDUCATIONAL PSYCHOLOGY by Wei, Wenhua, Peng, Junya, Duan, Fang

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Interleukin-17 activates and synergizes with the notch signaling pathway in the progression of pancreatic ductal adenocarcinoma by Wang, Xianze, Chen, Hao, Jiang, Rui, Hong, Xiafei, Peng, Junya, Chen, Wenyan, Jiang, Jialin, Li, Jie, Huang, Dan, Dai, Hongmei, Wang, Wenze, Lu, Junliang, Zhao, Yupei, Wu, Wenming

“…Interleukin (IL)-17 is a prominent cytokine that promotes pancreatic intraepithelial neoplasia (PanIN) and pancreatic ductal adenocarcinoma (PDAC) and is…”
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Pancreatic cancer cell-derived migrasomes promote cancer progression by fostering an immunosuppressive tumor microenvironment by Zhang, Ronghua, Peng, Junya, Zhang, Yalu, Zheng, Kexin, Chen, Yang, Liu, Lulu, Li, Tong, Liu, Jingkai, Li, Ying, Yang, Sen, Wang, Mengyi, Cui, Ming, Zhang, Xiang, Gao, Junyi, Kleeff, Jorg, Liao, Quan, Liu, Qiaofei

“…Pancreatic cancer is distinguished by an immunosuppressive tumor microenvironment (TME) that facilitates cancer progression. The assembly of the TME involves…”
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CXCL5 overexpression predicts a poor prognosis in pancreatic ductal adenocarcinoma and is correlated with immune cell infiltration by Zhang, Ronghua, Liu, Qiaofei, Peng, Junya, Wang, Mengyi, Li, Tong, Liu, Jingkai, Cui, Ming, Zhang, Xiang, Gao, Xiang, Liao, Quan, Zhao, Yupei

“…: C-X-C motif chemokine 5 (CXCL5) is an important attractant for immune cell accumulation in tumor tissues. Recent evidence has shown that CXCL5 could promote…”
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Uncovering chromatin accessibility and cancer diagnostic potential via cell-free DNA utilization by Li, Jie, Chen, Jiahui, Sun, Xin, Yang, Heli, Sun, Keyong, Liu, Chang, Wang, Yongwang, Xu, Mengyue, Ji, Xin, Zhang, Ji, Wu, Xiaojiang, Wang, Anqiang, Fan, Biao, Zhang, Xiaolu, Wu, Yue, Cui, Peilin, Peng, Junya, Zhao, Yupei, Wu, Wenming, Yu, Honghao, Bu, Zhaode, Ji, Jiafu, Lan, Xun

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Abstract C069: A conserved reepithelialization program driven by FOSL1 underlies malignancy in pancreatic ductal adenocarcinoma by David, Charles, Zhuo, Melian, Li, Yong, Zhang, Yifeng, Yang, Chenlu, Deng, Ziqing, Zhao, Yupei, Wu, Wennming, Peng, Junya, Chen, Mo

“…Abstract Benign lesions named pancreatic intraepithelial neoplasia (PanIN) are frequent in the healthy population but are precursors to deadly pancreatic…”
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Dapper1 promotes autophagy by enhancing the Beclin1-Vps34-Atg14L complex formation by Ma, Benyu, Cao, Weipeng, Li, Wenxia, Gao, Chan, Qi, Zhen, Zhao, Yan, Du, Jun, Xue, Hua, Peng, Junya, Wen, Jun, Chen, Hua, Ning, Yuanheng, Huang, Lei, Zhang, Hong, Gao, Xiang, Yu, Li, Chen, Ye-Guang

“…Autophagy is an intracellular degradation process to clear up aggregated proteins or aged and damaged organelles. The Beclin1-Vps34-Atg14L complex is essential…”
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