Search Results - "Peng, Henry"

Hemostatic agents for prehospital hemorrhage control: a narrative review by Peng, Henry T

“…Hemorrhage is the leading cause of preventable death in combat trauma and the secondary cause of death in civilian trauma. A significant number of deaths due…”
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Thromboelastography and Thromboelastometry in Assessment of Fibrinogen Deficiency and Prediction for Transfusion Requirement: A Descriptive Review by Peng, Henry T., Beckett, Andrew, Nascimento, Bartolomeu

“…Fibrinogen is crucial for the formation of blood clot and clinical outcomes in major bleeding. Both Thromboelastography (TEG) and Rotational Thromboelastometry…”
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Past meets present: Reviving 80‐year‐old Canadian dried serum from World War II and its significance in advancing modern freeze‐dried plasma for prehospital management of haemorrhage by Singh, Kanwal, Peng, Henry T., Moes, Katy, Kretz, Colin A., Beckett, Andrew

“…Summary During World War II, Charles H. Best utilized Charles R. Drew's plasma isolation and drying technique to lead Canada's initiative to provide dried…”
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Ex vivo hemostatic and immuno‐inflammatory profiles of freeze‐dried plasma by Peng, Henry T., Rhind, Shawn G., Devine, Dana, Jenkins, Craig, Beckett, Andrew

“…Background Hemorrhage is a leading cause of preventable death in civilian and military trauma. Freeze‐dried plasma is promising for hemostatic resuscitation in…”
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Freeze‐dried plasma: From damage control resuscitation to coronavirus disease 2019 therapy by Peng, Henry T., Rhind, Shawn G., Moes, Katy, Devine, Dana, Jenkins, Craig, Beckett, Andrew

“…Background Freeze‐dried plasma (FDP) is a promising blood component for prehospital resuscitation given its logistic advantages over fresh frozen plasma (FFP)…”
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An improved model to predict performance under mental fatigue by Peng, Henry T, Bouak, Fethi, Wang, Wenbi, Chow, Renee, Vartanian, Oshin

“…Fatigue has become an increasing problem in our modern society. Using MATLAB as a generic modelling tool, a fatigue model was developed based on an existing…”
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A comparative study of viscoelastic hemostatic assays and conventional coagulation tests in trauma patients receiving fibrinogen concentrate by Peng, Henry T., Nascimento, Bartolomeu, Tien, Homer, Callum, Jeannie, Rizoli, Sandro, Rhind, Shawn G., Beckett, Andrew

“…Both thrombelastography (TEG) and rotational thromboelastometry (ROTEM) have been investigated for diagnosis of coagulopathy and guidance of resuscitation in…”
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Evaluation of trauma‐induced coagulopathy in the fibrinogen in the initial resuscitation of severe trauma trial by Peng, Henry T., Nascimento, Barto, Rhind, Shawn G., Luz, Luis, Beckett, Andrew

“…Background Coagulopathic bleeding is frequently present after major trauma. However, trauma‐induced coagulopathy (TIC) remains incompletely understood. This…”
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Thromboelastographic study of biomaterials by Peng, Henry T.

“…Thromboelastography (TEG) is drawing more attention for clinical and in vitro studies of blood coagulation. It can be applied to evaluate the effects of both…”
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Stability of Reconstituted Fibrinogen Concentrate in Hemostatic Function and Concentration by Peng, Henry T, Beckett, Andrew

“…ABSTRACT Introduction Canadian Armed Forces adopted fibrinogen concentrate (RiaSTAP) for hemostatic resuscitation in the far-forward combat setting, given its…”
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Convalescent Plasma for the Prevention and Treatment of COVID-19: A Systematic Review and Quantitative Analysis by Peng, Henry T, Rhind, Shawn G, Beckett, Andrew

“…The COVID-19 pandemic, caused by a novel coronavirus termed SARS-CoV-2, has spread quickly worldwide. Convalescent plasma (CP) obtained from patients following…”
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Sympathoadrenal Activation is Associated with Acute Traumatic Coagulopathy and Endotheliopathy in Isolated Brain Injury by Di Battista, Alex P, Rizoli, Sandro B, Lejnieks, Brandon, Min, Arimie, Shiu, Maria Y, Peng, Henry T, Baker, Andrew J, Hutchison, Michael G, Churchill, Nathan, Inaba, Kenji, Nascimento, Bartolomeu B, de Oliveira Manoel, Airton Leonardo, Beckett, Andrew, Rhind, Shawn G

“…BACKGROUND:Acute coagulopathy after traumatic brain injury (TBI) involves a complex multifactorial hemostatic response that is poorly characterized…”
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Dried Plasma for Major Trauma: Past, Present, and Future by Peng, Henry T, Singh, Kanwal, Rhind, Shawn G, da Luz, Luis, Beckett, Andrew

“…Uncontrollable bleeding is recognized as the leading cause of preventable death among trauma patients. Early transfusion of blood products, especially plasma…”
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Artificial intelligence and machine learning for hemorrhagic trauma care by Peng, Henry T, Siddiqui, M Musaab, Rhind, Shawn G, Zhang, Jing, da Luz, Luis Teodoro, Beckett, Andrew

“…Artificial intelligence (AI), a branch of machine learning (ML) has been increasingly employed in the research of trauma in various aspects. Hemorrhage is the…”
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A physiologically based pharmacokinetics model for melatonin—Effects of light and routes of administration by Peng, Henry T., Bouak, Fethi, Vartanian, Oshin, Cheung, Bob

“…Physiologically based pharmacokinetic (PBPK) models were developed using MATLAB Simulink® to predict diurnal variations of endogenous melatonin with light as…”
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A comparative study of tissue factor and kaolin on blood coagulation assays using rotational thromboelastometry and thromboelastography by Peng, Henry T, Grodecki, Richard, Rizoli, Sandro, Shek, Pang N

“…Rotational thromboelastometry (ROTEM) and thromboelastography (TEG) have been increasingly used to diagnose acute coagulopathy and guide blood transfusion. The…”
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Post-Reconstitution Hemostatic Stability Profiles of Canadian and German Freeze-Dried Plasma by Peng, Henry T, Moes, Katherine, Singh, Kanwal, Rhind, Shawn G, Pambrun, Chantale, Jenkins, Craig, da Luz, Luis, Beckett, Andrew

“…Despite the importance of the hemostatic properties of reconstituted freeze-dried plasma (FDP) for trauma resuscitation, few studies have been conducted to…”
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In Trauma, Conventional ROTEM and TEG Results Are Not Interchangeable But Are Similar in Clinical Applicability by Rizoli, Sandro, Min, Arimie, Sanchez, Adic Perez, Shek, Pang, Grodecki, Richard, Veigas, Precilla, Peng, Henry T

“…There is growing interest in viscoelastic hemostatic assays rotational thromboelastometry (ROTEM) and thromboelastography (TEG) for trauma. Despite shared…”
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Novel wound sealants: biomaterials and applications by Peng, Henry T, Shek, Pang N

“…Wound sealants provide an excellent alternative for closing surgical and non-surgical wounds, as well as stopping external bleeding for prehospital trauma…”
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Protocol for a multicentre, randomised, parallel-control, superiority trial comparing administration of clotting factor concentrates with a standard massive haemorrhage protocol in severely bleeding trauma patients: the FiiRST 2 trial (a 2020 EAST multicentre trial) by da Luz, Luis Teodoro, Callum, Jeannie, Beckett, Andrew, Hucke, Hans-Peter, Carroll, Jo, Grewal, Deep, Schwartz, Bruce, Peng, Henry, Engels, Paul T, Parry, Neil, Petrosoniak, Andrew, Tien, Homer, Nathens, Avery B, Scales, Damon, Karkouti, Keyvan

“…IntroductionAcute traumatic coagulopathy (ATC) in bleeding trauma patients increase in-hospital mortality. Fibrinogen concentrate (FC) and prothrombin complex…”
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