Search Results - "Pendleton, C"

A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing by Kimmel, Stephen E, French, Benjamin, Kasner, Scott E, Johnson, Julie A, Anderson, Jeffrey L, Gage, Brian F, Rosenberg, Yves D, Eby, Charles S, Madigan, Rosemary A, McBane, Robert B, Abdel-Rahman, Sherif Z, Stevens, Scott M, Yale, Steven, Mohler, Emile R, Fang, Margaret C, Shah, Vinay, Horenstein, Richard B, Limdi, Nita A, Muldowney, James A.S, Gujral, Jaspal, Delafontaine, Patrice, Desnick, Robert J, Ortel, Thomas L, Billett, Henny H, Pendleton, Robert C, Geller, Nancy L, Halperin, Jonathan L, Goldhaber, Samuel Z, Caldwell, Michael D, Califf, Robert M, Ellenberg, Jonas H

“…In this trial, 1015 patients were assigned to the use of either a genotype-guided algorithm or a clinically guided algorithm for warfarin dosing during the…”
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VTE Incidence and Risk Factors in Patients With Severe Sepsis and Septic Shock by Kaplan, David, Drs, Casper, T. Charles, Dr, Elliott, C. Gregory, Drs, Men, Shaohua, Mr, Pendleton, Robert C., MD, Kraiss, Larry W., Dr, Weyrich, Andrew S., Drs, Grissom, Colin K., MD, Zimmerman, Guy A., MD, Rondina, Matthew T., MD

“…BACKGROUND Prospective studies on the incidence of VTE during severe sepsis and septic shock remain absent, hindering efficacy assessments regarding VTE…”
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Increased virulence due to multiple infection in Daphnia leads to limited growth in 1 of 2 co-infecting microsporidian parasites by O'Keeffe, Floriane E., Pendleton, Rebecca C., Holland, Celia V., Luijckx, Pepijn

“…Recent outbreaks of various infectious diseases have highlighted the ever-present need to understand the drivers of the outbreak and spread of disease…”
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Integration of Genetic, Clinical, and INR Data to Refine Warfarin Dosing by Lenzini, P, Wadelius, M, Kimmel, S, Anderson, J L, Jorgensen, A L, Pirmohamed, M, Caldwell, M D, Limdi, N, Burmester, J K, Dowd, M B, Angchaisuksiri, P, Bass, A R, Chen, J, Eriksson, N, Rane, A, Lindh, J D, Carlquist, J F, Horne, B D, Grice, G, Milligan, P E, Eby, C, Shin, J, Kim, H, Kurnik, D, Stein, C M, McMillin, G, Pendleton, R C, Berg, R L, Deloukas, P, Gage, B F

“…Well‐characterized genes that affect warfarin metabolism (cytochrome P450 (CYP) 2C9) and sensitivity (vitamin K epoxide reductase complex 1 (VKORC1)) explain…”
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Correction: Evaluating the detection ability of a range of epistasis detection methods on simulated data for pure and impure epistatic models by Russ, Dominic, Williams, John A, Cardoso, Victor Roth, Bravo-Merodio, Laura, Pendleton, Samantha C, Aziz, Furqan, Acharjee, Animesh, Gkoutos, Georgios V

“…[This corrects the article DOI: 10.1371/journal.pone.0263390.]…”
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Evaluating the detection ability of a range of epistasis detection methods on simulated data for pure and impure epistatic models by Russ, Dominic, Williams, John A, Cardoso, Victor Roth, Bravo-Merodio, Laura, Pendleton, Samantha C, Aziz, Furqan, Acharjee, Animesh, Gkoutos, Georgios V

“…Numerous approaches have been proposed for the detection of epistatic interactions within GWAS datasets in order to better understand the drivers of disease…”
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Protecting endangered species in the USA requires both public and private land conservation by Clancy, Niall G., Draper, John P., Wolf, J. Marshall, Abdulwahab, Umarfarooq A., Pendleton, Maya C., Brothers, Soren, Brahney, Janice, Weathered, Jennifer, Hammill, Edd, Atwood, Trisha B.

“…Crucial to the successful conservation of endangered species is the overlap of their ranges with protected areas. We analyzed protected areas in the…”
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Genome-wide Gene-by-Sex Interaction Studies Identify Novel Nonsyndromic Orofacial Clefts Risk Locus by Awotoye, W., Comnick, C., Pendleton, C., Zeng, E., Alade, A., Mossey, P.A., Gowans, L.J.J., Eshete, M.A., Adeyemo, W.L., Naicker, T., Adeleke, C., Busch, T., Li, M., Petrin, A., Olotu, J., Hassan, M., Pape, J., Miller, S.E., Donkor, P., Anand, D., Lachke, S.A., Marazita, M.L., Adeyemo, A.A., Murray, J.C., Albokhari, D., Sobreira, N., Butali, A.

“…Risk loci identified through genome-wide association studies have explained about 25% of the phenotypic variations in nonsyndromic orofacial clefts (nsOFCs) on…”
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Multimorbidity prediction using link prediction by Aziz, Furqan, Cardoso, Victor Roth, Bravo-Merodio, Laura, Russ, Dominic, Pendleton, Samantha C., Williams, John A., Acharjee, Animesh, Gkoutos, Georgios V.

“…Multimorbidity, frequently associated with aging, can be operationally defined as the presence of two or more chronic conditions. Predicting the likelihood of…”
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Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy by Horne, Benjamin D, Lenzini, Petra A, Wadelius, Mia, Jorgensen, Andrea L, Kimmel, Stephen E, Ridker, Paul M, Eriksson, Niclas, Anderson, Jeffrey L, Pirmohamed, Munir, Limdi, Nita A, Pendleton, Robert C, McMillin, Gwendolyn A, Burmester, James K, Kurnik, Daniel, Stein, C Michael, Caldwell, Michael D, Eby, Charles S, Rane, Anders, Lindh, Jonatan D, Shin, Jae-Gook, Kim, Ho-Sook, Angchaisuksiri, Pantep, Glynn, Robert J, Kronquist, Kathryn E, Carlquist, John F, Grice, Gloria R, Barrack, Robert L, Li, Juan, Gage, Brian F

“…By guiding initial warfarin dose, pharmacogenetic (PGx) algorithms may improve the safety of warfarin initiation. However, once international normalised ratio…”
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Identification and enhancement of HLA-A2.1-restricted CTL epitopes in a new human cancer antigen-POTE by Huang, Yi-Hsiang, Terabe, Masaki, Pendleton, C David, Stewart Khursigara, Deborah, Bera, Tapan K, Pastan, Ira, Berzofsky, Jay A

“…Identification of CD8(+) T cell epitopes that can induce T cells to kill tumor cells is a fundamental step for development of a peptide cancer vaccine. POTE…”
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Immunization With Mutant p53- and K-ras–Derived Peptides in Cancer Patients: Immune Response and Clinical Outcome by CARBONE, David P, CIERNIK, I. Frank, PENDLETON, C. David, SEIFERT, Burkhardt, CARTER, Charley, READ, Elizabeth J, GREENBLATT, Jay, TOP, Lois E, KELSEY, Morris I, MINNA, John D, BERZOFSKY, Jay A, KELLEY, Michael J, SMITH, M. Charles, NADAF, Sorena, KAVANAUGH, Denise, MAHER, V. Ellen, STIPANOV, Michael, CONTOIS, David, JOHNSON, Bruce E

“…To determine the ability to induce tumor-specific immunity with individual mutant K-ras-or p53-derived peptides and to monitor clinical outcome. Patients in…”
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Commentary: The Role of PET Scan Uptake in Determining Prognosis in Early-Stage Lung Cancer by Pendleton, Audrey C.

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Association between Dental Anomalies and Orofacial Clefts: A Meta-analysis by Marzouk, T., Alves, I.L., Wong, C.L., DeLucia, L., McKinney, C.M., Pendleton, C., Howe, B.J., Marazita, M.L., Peter, T.K., Kopycka-Kedzierawski, D.T., Morrison, C.S., Malmstrom, H., Wang, H., Shope, E.T.

“…Objectives: To conduct a systematic review and meta-analysis to assess whether individuals with nonsyndromic orofacial clefts (OCs) display a higher frequency…”
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Genetics informatics trial (GIFT) of warfarin to prevent deep vein thrombosis (DVT): rationale and study design by Do, E J, Lenzini, P, Eby, C S, Bass, A R, McMillin, G A, Stevens, S M, Woller, S C, Pendleton, R C, Anderson, J L, Proctor, P, Nunley, R M, Davila-Roman, V, Gage, B F

“…The risk of venous thromboembolism (VTE) is higher after the total hip or knee replacement surgery than after almost any other surgical procedure; warfarin…”
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18F-FDG PET in the Evaluation of Acuity of Deep Vein Thrombosis by Rondina, Matthew T, Lam, Uyen T, Pendleton, Robert C, Kraiss, Larry W, Wanner, Nathan, Zimmerman, Guy A, Hoffman, John M, Hanrahan, Christopher, Boucher, Kenneth, Christian, Paul E, Butterfield, Regan I, Morton, Kathryn A

“…PURPOSEF-FDG PET has been used for vascular disease, but its role in deep vein thrombosis (DVT) remains prospectively unexplored. PATIENTS AND…”
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Laparoscopic Transhiatal Esophagectomy With En Bloc Posterior Tracheal Wall Resection by Pendleton, Audrey C., Stenson, Kerstin, Tabachnick, Deborah, Seder, Christopher W.

“…Esophageal adenoid cystic carcinoma is a rare cancer that is a challenge to treat because the tumor often invades local structures. Complete resection with…”
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Implementation of a Value-Driven Outcomes Program to Identify High Variability in Clinical Costs and Outcomes and Association With Reduced Cost and Improved Quality by Lee, Vivian S, Kawamoto, Kensaku, Hess, Rachel, Park, Charlton, Young, Jeffrey, Hunter, Cheri, Johnson, Steven, Gulbransen, Sandi, Pelt, Christopher E, Horton, Devin J, Graves, Kencee K, Greene, Tom H, Anzai, Yoshimi, Pendleton, Robert C

“…IMPORTANCE: Transformation of US health care from volume to value requires meaningful quantification of costs and outcomes at the level of individual patients…”
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Human CTLs to wild-type and enhanced epitopes of a novel prostate and breast tumor-associated protein, TARP, lyse human breast cancer cells by OH, Sangkon, TERABE, Masaki, PASTAN, Ira, BERZOFSKY, Jay A, PENDLETON, C. David, BHATTACHARYYA, Anu, BERA, Tapan K, EPEL, Malka, REITER, Yoram, PHILLIPS, John, LINEHAN, W. Marston, KASTEN-SPORTES, Claude

“…Vaccine therapy for prostate and breast cancer may have potential for treating these major causes of death in males and females, respectively. Critical to the…”
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Proliferation and pluripotency of human embryonic stem cells maintained on type I collagen by Jones, Meredith B, Chu, Chia H, Pendleton, James C, Betenbaugh, Michael J, Shiloach, Joseph, Baljinnyam, Bolormaa, Rubin, Jeffrey S, Shamblott, Michael J

“…Human embryonic stem cells (hESC) require a balance of growth factors and signaling molecules to proliferate and retain pluripotency. Conditioned medium (CM)…”
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