Search Results - "Pender, MP"

Infection of autoreactive B lymphocytes with EBV, causing chronic autoimmune diseases by Pender, Michael P.

“…I hypothesize that human chronic autoimmune diseases are based on infection of autoreactive B lymphocytes by Epstein–Barr virus (EBV), in the following…”
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Population attributable fractions and joint effects of key risk factors for multiple sclerosis by van der Mei, IAF, Lucas, RM, Taylor, BV, Valery, PC, Dwyer, T, Kilpatrick, TJ, Pender, MP, Williams, D, Chapman, C, Otahal, P, Ponsonby, A-L

“…Aim: We examined the combined effect of having multiple key risk factors and the interactions between the key risk factors of multiple sclerosis (MS). Methods:…”
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Apoptosis of inflammatory cells in immune control of the nervous system: Role of glia by Pender, Michael P., Rist, Michael J.

“…The elimination of inflammatory cells within the central nervous system (CNS) by apoptosis plays an important role in protecting the CNS from immune‐mediated…”
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Immune dysregulation and self-reactivity in schizophrenia: Do some cases of schizophrenia have an autoimmune basis? by Jones, Amanda L, Mowry, Bryan J, Pender, Michael P, Greer, Judith M

“…Schizophrenia affects 1% of the world's population, but its cause remains obscure. Numerous theories have been proposed regarding the cause of schizophrenia,…”
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T cell reactivity to P0, P2, PMP-22, and myelin basic protein in patients with Guillain-Barré syndrome and chronic inflammatory demyelinating polyradiculoneuropathy by Csurhes, P A, Sullivan, A-A, Green, K, Pender, M P, McCombe, P A

“…Objectives: It has been suggested that autoimmunity to peripheral myelin proteins is involved in the pathogenesis of Guillain-Barré syndrome (GBS) and chronic…”
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The presence of glutamic acid at positions 71 or 74 in pocket 4 of the HLA-DR beta 1 chain is associated with the clinical course of multiple sclerosis by Greer, J M, Pender, M P

“…BACKGROUND: Primary progressive multiple sclerosis (PP-MS) differs from relapsing-remitting or secondary progressive MS (RR/SP-MS) in ways suggesting…”
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Observational analytic studies in multiple sclerosis: controlling bias through study design and conduct. The Australian Multicentre Study of Environment and Immune Function by Lucas, RM, Ponsonby, A-L., McMichael, AJ, van der Mei, I., Chapman, C., Coulthard, A., Dear, K., Dwyer, T., Kilpatrick, TJ, Pender, MP, Taylor, B., Valery, P., Williams, D.

“…Rising multiple sclerosis incidence over the last 50 years and geographic patterns of occurrence suggest an environmental role in the causation of this…”
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Genetically determined failure of activation-induced apoptosis of autoreactive T cells as a cause of multiple sclerosis by Pender, Michael P

“…I postulate that multiple sclerosis is an autoimmune disease that Involves genetically determined failure of activation-Induced apoptosis of autoreactive T…”
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T-cell apoptosis in human glioblastoma multiforme: Implications for immunotherapy by Walker, David G., Chuah, Teong, Rist, Michael J., Pender, Michael P.

“…We used immunohistochemistry and flow cytometry to assess apoptosis in human glioblastoma multiforme (GBM). Our immunohistochemical study revealed apoptosis of…”
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Blood–brain barrier disruption and lesion localisation in experimental autoimmune encephalomyelitis with predominant cerebellar and brainstem involvement by Muller, Diane M., Pender, Michael P., Greer, Judith M.

“…The role of the blood–brain barrier (BBB) in determining lesion distribution was assessed in an atypical model of experimental autoimmune encephalomyelitis…”
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Strains of Epstein-Barr virus infecting multiple sclerosis patients by Brennan, RM, Burrows, JM, Bell, MJ, Bromham, L., Csurhes, PA, Lenarczyk, A., Sverndal, J., Klintenstedt, J., Pender, MP, Burrows, SR

“…Both epidemiological and experimental studies have indicated that the ubiquitous herpesvirus Epstein—Barr virus (EBV) plays a role in the pathogenesis of…”
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CSF testing for multiple sclerosis by Pender, Michael P

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Increased circulating antiganglioside antibodies in primary and secondary progressive multiple sclerosis by Sadatipour, B T, Greer, J M, Pender, M P

“…Plasma samples from 70 patients with multiple sclerosis (MS), 41 patients with other neurological diseases (OND), and 38 healthy subjects were examined for…”
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Prominent brainstem and cerebellar involvement in multiple sclerosis with psoriasis by Ganesvaran, G, Greer, JM, Pender, MP

“…Introduction We identified a subgroup of 20 patients with multiple sclerosis (MS) and psoriasis within a total group of 692 patients with MS. Results There was…”
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Activation-induced apoptosis of autoreactive and alloreactive T lymphocytes in the target organ as a major mechanism of tolerance by Pender, Michael P

“…Normal individuals have mature T lymphocytes that are capable of reacting to self‐antigens and can be activated by cross‐reacting environmental antigens. The…”
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Oligodendrocyte apoptosis before immune attack in multiple sclerosis? by Pender, Michael P.

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Apoptotic elimination of V beta 8.2+ cells from the central nervous system during recovery from experimental autoimmune encephalomyelitis induced by the passive transfer of V beta 8.2+ encephalitogenic T cells by Tabi, Z, McCombe, P A, Pender, M P

“…A CD4+V beta 8.2+ T cell clone specific for the peptide 72-89 of guinea pig myelin basic protein (GMBP) was used to induce acute experimental autoimmune…”
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Genetic investigation of methylenetetrahydrofolate reductase (MTHFR) and catechol- O-methyl transferase (COMT) in multiple sclerosis by Tajouri, Lotti, Martin, Virginie, Gasparini, Claudia, Ovcaric, Micky, Curtain, Rob, Lea, Rod A., Haupt, Larisa M., Csurhes, Peter, Pender, Michael P., Griffiths, Lyn R.

“…Multiple sclerosis (MS) is a chronic neurological disease characterized by central nervous system (CNS) inflammation and demyelination. The C677T substitution…”
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The occurrence of autoimmune diseases in patients with multiple sclerosis and their families by Henderson, Robert D., Bain, Christopher J., Pender, Michael P.

“…The aims of this study were to determine whether the occurrence of autoimmune diseases is increased in patients with multiple sclerosis (MS) and their families…”
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Apneusis responding to buspirone in multiple sclerosis by O’Sullivan, RJ, Brown, IG, Pender, MP

“…Apneusis is a disturbance of respiratory rhythm characterized by severely prolonged inspiratory effort, and is caused by bilateral lesions in the dorsal pons…”
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