Search Results - "Pencikova, K"

Investigation of sanguinarine and chelerythrine effects on LPS-induced inflammatory gene expression in THP-1 cell line by Pencikova, K, Kollar, P, Zavalova, Muller V, Taborska, E, Urbanova, J, Hosek, J

“…Quaternary benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine have been used in folk medicine for their wide range of useful properties. One of…”
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P21-58 AhR-activating polycyclic aromatic hydrocarbons disrupt metabolic pathways in human hepatocyte-like cells by Vondracek, J., Petras, J., Simeckova, P., Pencikova, K., Dvorak, Z., Machala, M.

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Effects of methylated chrysenes on AhR-dependent and -independent toxic events in rat liver epithelial cells by Machala, M, Švihálková-Šindlerová, L, Pěnčíková, K, Krčmář, P, Topinka, J, Milcová, A, Nováková, Z, Kozubík, A, Vondráček, J

“…Abstract Methylated chrysenes (MeChry) are important cigarette smoke constituents and 5-MeChry has been listed as possibly carcinogenic to humans. Although a…”
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Dibenzanthracenes and benzochrysenes elicit both genotoxic and nongenotoxic events in rat liver ‘stem-like’ cells by Švihálková-Šindlerová, L, Machala, M, Pěnčíková, K, Marvanová, S, Neča, J, Topinka, J, Sevastyanova, O, Kozubík, A, Vondráček, J

“…Abstract Polycyclic aromatic hydrocarbons (PAHs) with molecular weight 278 are a group of PAHs that are mostly not covered by the current monitoring programs,…”
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Differential responses to PAHs and dioxin-like compounds in human and rat AhR-dependent reporter gene cell models by Pencikova, K., Vondracek, J., Dvorak, Z., Novotna, A., Andersson, P., Machala, M.

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Modulation of sphingolipid metabolism and alterations of membrane proteins by dioxin- and non-dioxin-like toxicants in liver progenitor cells by Machala, M., Slavik, J., Pencikova, K., Vondracek, J.

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Consensus Toxicity Factors for Polychlorinated Dibenzo‑p‑dioxins, Dibenzofurans, and Biphenyls Combining in Silico Models and Extensive in Vitro Screening of AhR-Mediated Effects in Human and Rodent Cells by Larsson, Malin, van den Berg, Martin, Brenerová, Petra, van Duursen, Majorie B. M, van Ede, Karin I, Lohr, Christiane, Luecke-Johansson, Sandra, Machala, Miroslav, Neser, Sylke, Pěnčíková, Kateřina, Poellinger, Lorenz, Schrenk, Dieter, Strapáčová, Simona, Vondráček, Jan, Andersson, Patrik L

“…Consensus toxicity factors (CTFs) were developed as a novel approach to establish toxicity factors for risk assessment of dioxin-like compounds (DLCs)…”
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Comparative analysis of the toxic responses of organic extracts from diesel/biodiesel engine emissions in human lung BEAS-2B cells by Libalova, H., Vrbova, K., Brzicova, T., Sikorova, J., Milcova, A., Vojtisek Lom, M., Beranek, V., Klema, J., Neca, J., Ciganek, M., Machala, M., Pencikova, K., Topinka, J.

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DNA adducts formation and induction of apoptosis in rat liver epithelial 'stem-like' cells exposed to carcinogenic polycyclic aromatic hydrocarbons by Topinka, Jan, Marvanová, Sona, Vondrácek, Jan, Sevastyanova, Oksana, Nováková, Zuzana, Krcmár, Pavel, Pencíková, Katerina, Machala, Miroslav

“…The bipotent liver progenitor cells, so called oval cells, may participate at the early stages of hepatocarcinogenesis induced by chemical carcinogens. Unlike…”
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In Vitro and in Silico Derived Relative Effect Potencies of Ah-Receptor-Mediated Effects by PCDD/Fs and PCBs in Rat, Mouse, and Guinea Pig CALUX Cell Lines by Ghorbanzadeh, Mehdi, van Ede, Karin I, Larsson, Malin, van Duursen, Majorie B. M, Poellinger, Lorenz, Lücke-Johansson, Sandra, Machala, Miroslav, Pěnčíková, Kateřina, Vondráček, Jan, van den Berg, Martin, Denison, Michael S, Ringsted, Tine, Andersson, Patrik L

“…For a better understanding of species-specific relative effect potencies (REPs), responses of dioxin-like compounds (DLCs) were assessed. REPs were calculated…”
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Concentrations of methylated naphthalenes, anthracenes, and phenanthrenes occurring in Czech river sediments and their effects on toxic events associated with carcinogenesis in rat liver cell lines by Vondracek, J, Svihalkova-Sindlerova, L, Pencikova, K, Marvanova, S, Krcmar, P, Ciganek, M, Neca, J, Trosko, J.E, Upham, B, Kozubik, A

“…Alkylated polycyclic aromatic hydrocarbons (PAHs) are important environmental pollutants. In the present study, we determined levels of monomethylated…”
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Role of aryl hydrocarbon receptor in modulation of the expression of the hypoxia marker carbonic anhydrase IX by Takacova, Martina, Holotnakova, Tereza, Vondracek, Jan, Machala, Miroslav, Pencikova, Katerina, Gradin, Katarina, Poellinger, Lorenz, Pastorek, Jaromir, Pastorekova, Silvia, Kopacek, Juraj

“…Tumour-associated expression of CA IX (carbonic anhydrase IX) is to a major extent regulated by HIF-1 (hypoxia-inducible factor-1) which is important for…”
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Multiple effects of non-dioxin-like PCB 153 on plasmatic membrane, lipid signaling and cell-to-cell communication by Pencikova, Katerina, Simecková, Pavlína, Procházková, Jirina, Krcmar, Pavel, Umannová, Lenka, Slavík, Josef, Neca, Jirí, Vondrácek, Jan, Machala, Miroslav

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Effects of non-dioxin-like PCBs (NDL-PCBs) on signaling pathways contributing to liver tumor promotion and carcinogenesis by Machala, Miroslav, Simeckova, Pavlina, Al-Anati, Lauy, Stenius, Ulla, Pencikova, Katerina, Prochazkova, Jirina, Krcmar, Pavel, Slavik, Josef, Vondracek, Jan

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Identification and toxicological evaluation of musk fragrances and thiophenes in extracts of river sediment samples by Vykopalova, Lenka, Pencikova, Katerina, Ciganek, Miroslav, Neca, Jiri, Vondracek, Jan, Brack, Werner, Varel, Urte Luebcke-Von, Streck, G., Machala, Miroslav

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447 Acute exposure to polycyclic aromatic hydrocarbons affects multiple cell signaling components in rat liver epithelial cell line by Machala, M., Blaha, L., Kapplova, P., Pencikova, K., Neca, J., Andrysik, Z., Upham, B., Vondracek, J.

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7H-Dibenzo[c,g]carbazole and 5,9-dimethyldibenzo[c,g]carbazole exert multiple toxic events contributing to tumor promotion in rat liver epithelial 'stem-like' cells by Vondrácek, Jan, Svihálková-Sindlerová, Lenka, Pencíková, Katerina, Krcmár, Pavel, Andrysík, Zdenek, Chramostová, Katerina, Marvanová, Sona, Valovicová, Zuzana, Kozubík, Alois, Gábelová, Alena, Machala, Miroslav

“…Immature liver progenitor cells have been suggested to be an important target of hepatotoxins and hepatocarcinogens. The goal of the present study was to…”
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Contact sensitization to pharmaceutic aids in dermatologic cosmetic and external use preparations by Dastychová, E, Necas, M, Pĕncíková, K, Cerný, P

“…From April 2001 to December 2002, a group of 514 patients (178 men, 336 women, average age 42.8 years) suffering from chronic eczema were tested by means of…”
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