Search Results - "Penciková, Katerina"

Characterization of elements, PAHs, AhR-activity and pro-inflammatory responses of road tunnel-derived particulate matter in human hepatocyte-like and bronchial epithelial cells by Holme, Jørn A., Låg, Marit, Skuland, Tonje, Parenicová, Martina, Ciganek, Miroslav, Penciková, Katerina, Grytting, Vegard Sæter, Neca, Jiri, Øvrevik, Johan, Mariussen, Espen, Jørgensen, Rikke Bramming, Refsnes, Magne, Machala, Miroslav

“…The aims were to characterize the content of elements and polycyclic aromatic hydrocarbons (PAHs) in size-separated particulate matter (PM) sampled in a road…”
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Comparative Analysis of Toxic Responses of Organic Extracts from Diesel and Selected Alternative Fuels Engine Emissions in Human Lung BEAS-2B Cells by Libalova, Helena, Rossner, Pavel, Vrbova, Kristyna, Brzicova, Tana, Sikorova, Jitka, Vojtisek-Lom, Michal, Beranek, Vit, Klema, Jiri, Ciganek, Miroslav, Neca, Jiri, Pencikova, Katerina, Machala, Miroslav, Topinka, Jan

“…This study used toxicogenomics to identify the complex biological response of human lung BEAS-2B cells treated with organic components of particulate matter in…”
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Polar Compounds Dominate in Vitro Effects of Sediment Extracts by Lübcke-von Varel, Urte, Machala, Miroslav, Ciganek, Miroslav, Neca, Jiri, Pencikova, Katerina, Palkova, Lenka, Vondracek, Jan, Löffler, Ivonne, Streck, Georg, Reifferscheid, Georg, Flückiger-Isler, Sini, Weiss, Jana M, Lamoree, Marja, Brack, Werner

“…Sediment extracts from three polluted sites of the river Elbe basin were fractionated using a novel online fractionation procedure. Resulting fractions were…”
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In vitro profiling of toxic effects of environmental polycyclic aromatic hydrocarbons on nuclear receptor signaling, disruption of endogenous metabolism and induction of cellular stress by Šimečková, Pavlína, Pěnčíková, Kateřina, Kováč, Ondrej, Slavík, Josef, Pařenicová, Martina, Vondráček, Jan, Machala, Miroslav

“…Polycyclic aromatic hydrocarbons (PAHs) may interact with multiple intracellular receptors and related signaling pathways. We comprehensively evaluated the…”
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Assessment of the aryl hydrocarbon receptor-mediated activities of polycyclic aromatic hydrocarbons in a human cell-based reporter gene assay by Vondráček, Jan, Pěnčíková, Kateřina, Neča, Jiří, Ciganek, Miroslav, Grycová, Aneta, Dvořák, Zdeněk, Machala, Miroslav

“…Activation of the aryl hydrocarbon receptor (AhR)-mediated activity is one of key events in toxicity of polycyclic aromatic hydrocarbons (PAHs). Although…”
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Modulation of endocrine nuclear receptor activities by polyaromatic compounds present in fractionated extracts of diesel exhaust particles by Pěnčíková, Kateřina, Ciganek, Miroslav, Neča, Jiří, Illés, Peter, Dvořák, Zdeněk, Vondráček, Jan, Machala, Miroslav

“…Organic pollutants associated with diesel exhaust particles (DEP), such as polycyclic aromatic hydrocarbons (PAHs) and their derivatives, may negatively impact…”
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Aryl Hydrocarbon Receptor-Dependent Metabolism Plays a Significant Role in Estrogen-Like Effects of Polycyclic Aromatic Hydrocarbons on Cell Proliferation by Hýžd′alová, Martina, Pivnička, Jakub, Zapletal, Ondřej, Vázquez-Gómez, Gerardo, Matthews, Jason, Neča, Jiří, Pěnčíková, Kateřina, Machala, Miroslav, Vondráček, Jan

“…Abstract Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental contaminants that interact in a complex manner with both the aryl hydrocarbon…”
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Benzo[b]naphtho[d]thiophenes and naphthylbenzo[b]thiophenes: Their aryl hydrocarbon receptor-mediated activities and environmental presence by Marvanová, Soňa, Pěnčíková, Kateřina, Pálková, Lenka, Ciganek, Miroslav, Petráš, Jiří, Lněničková, Anna, Vondráček, Jan, Machala, Miroslav

“…Polycyclic aromatic sulfur heterocyclic compounds (PASHs) belong among ubiquitous environmental pollutants; however, their toxic effects remain poorly…”
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Changes in Sphingolipid Profile of Benzo[a]pyrene-Transformed Human Bronchial Epithelial Cells Are Reflected in the Altered Composition of Sphingolipids in Their Exosomes by Machala, Miroslav, Slavík, Josef, Kováč, Ondrej, Procházková, Jiřina, Pěnčíková, Kateřina, Pařenicová, Martina, Straková, Nicol, Kotouček, Jan, Kulich, Pavel, Mollerup, Steen, Vondráček, Jan, Hýžďalová, Martina

“…Sphingolipids (SLs), glycosphingolipids (GSLs), and eicosanoids are bioactive lipids, which play important roles in the etiology of various diseases, including…”
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Gadolinium labelled nanoliposomes as the platform for MRI theranostics: in vitro safety study in liver cells and macrophages by Šimečková, Pavlína, Hubatka, František, Kotouček, Jan, Turánek Knötigová, Pavlína, Mašek, Josef, Slavík, Josef, Kováč, Ondrej, Neča, Jiří, Kulich, Pavel, Hrebík, Dominik, Stráská, Jana, Pěnčíková, Kateřina, Procházková, Jiřina, Diviš, Pavel, Macaulay, Stuart, Mikulík, Robert, Raška, Milan, Machala, Miroslav, Turánek, Jaroslav

“…Gadolinium (Gd)–based contrast agents are extensively used for magnetic resonance imaging (MRI). Liposomes are potential nanocarrier–based biocompatible…”
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Environmental six-ring polycyclic aromatic hydrocarbons are potent inducers of the AhR-dependent signaling in human cells by Vondráček, Jan, Pěnčíková, Kateřina, Ciganek, Miroslav, Pivnička, Jakub, Karasová, Martina, Hýžďalová, Martina, Strapáčová, Simona, Pálková, Lenka, Neča, Jiří, Matthews, Jason, Lom, Michal Vojtíšek, Topinka, Jan, Milcová, Alena, Machala, Miroslav

“…The toxicities of many environmental polycyclic aromatic hydrocarbons (PAHs), in particular those of high-molecular-weight PAHs (with MW higher than 300),…”
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Activation of the aryl hydrocarbon receptor is the major toxic mode of action of an organic extract of a reference urban dust particulate matter mixture: the role of polycyclic aromatic hydrocarbons by Andrysík, Zdeněk, Vondráček, Jan, Marvanová, Soňa, Ciganek, Miroslav, Neča, Jiří, Pěnčíková, Kateřina, Mahadevan, Brinda, Topinka, Jan, Baird, William M, Kozubík, Alois, Machala, Miroslav

“…Many of the toxic and carcinogenic effects of urban air pollution have been linked to polycyclic aromatic hydrocarbons (PAHs) adsorbed to airborne particulate…”
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Day-to-day variability of toxic events induced by organic compounds bound to size segregated atmospheric aerosol by Topinka, Jan, Rossner, Pavel, Milcová, Alena, Schmuczerová, Jana, Pěnčíková, Kateřina, Rossnerová, Andrea, Ambrož, Antonín, Štolcpartová, Jitka, Bendl, Jan, Hovorka, Jan, Machala, Miroslav

“…This study quantified the temporal variability of concentration of carcinogenic polycyclic aromatic hydrocarbons (c-PAHs), genotoxicity, oxidative DNA damage…”
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Transcriptional and phenotypical alterations associated with a gradual benzo[a]pyrene-induced transition of human bronchial epithelial cells into mesenchymal-like cells by Hýžďalová, Martina, Procházková, Jiřina, Straková, Nicol, Pěnčíková, Kateřina, Strapáčová, Simona, Slováčková, Jana, Kajabová, Simona, Líbalová, Helena, Topinka, Jan, Kabátková, Markéta, Vondráček, Jan, Mollerup, Steen, Machala, Miroslav

“…The role of benzo[a]pyrene (BaP), a prominent genotoxic carcinogen and aryl hydrocarbon receptor (AhR) ligand, in tumor progression remains poorly…”
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Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands by Procházková, Jiřina, Strapáčová, Simona, Svržková, Lucie, Andrysík, Zdeněk, Hýžďalová, Martina, Hrubá, Eva, Pěnčíková, Kateřina, Líbalová, Helena, Topinka, Jan, Kléma, Jiří, Espinosa, Joaquín M., Vondráček, Jan, Machala, Miroslav

“…[Display omitted] •Global gene profiling of AhR-dependent changes in lung cancer cells transcriptome.•Acute exposure to TCDD, BaP, BkF, ITE and FICZ shows…”
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Consensus Toxicity Factors for Polychlorinated Dibenzo‑p‑dioxins, Dibenzofurans, and Biphenyls Combining in Silico Models and Extensive in Vitro Screening of AhR-Mediated Effects in Human and Rodent Cells by Larsson, Malin, van den Berg, Martin, Brenerová, Petra, van Duursen, Majorie B. M, van Ede, Karin I, Lohr, Christiane, Luecke-Johansson, Sandra, Machala, Miroslav, Neser, Sylke, Pěnčíková, Kateřina, Poellinger, Lorenz, Schrenk, Dieter, Strapáčová, Simona, Vondráček, Jan, Andersson, Patrik L

“…Consensus toxicity factors (CTFs) were developed as a novel approach to establish toxicity factors for risk assessment of dioxin-like compounds (DLCs)…”
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Interactive effects of inflammatory cytokine and abundant low-molecular-weight PAHs on inhibition of gap junctional intercellular communication, disruption of cell proliferation control, and the AhR-dependent transcription by Kabátková, Markéta, Svobodová, Jana, Pěnčíková, Kateřina, Mohatad, Dilshad Shaik, Šmerdová, Lenka, Kozubík, Alois, Machala, Miroslav, Vondráček, Jan

“…•TNF-α inhibits GJIC and decreases Cx43 in liver epithelial cells.•TNF-α potentiates induction of cell cycle progression elicited by fluoranthene.•TNF-α…”
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Atropisomers of 2,2′,3,3′,6,6′-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro by Pěnčíková, Kateřina, Brenerová, Petra, Svržková, Lucie, Hrubá, Eva, Pálková, Lenka, Vondráček, Jan, Lehmler, Hans-Joachim, Machala, Miroslav

“…PCB 136 is an environmentally relevant chiral PCB congener, which has been found in vivo to be present in form of rotational isomers (atropisomers). Its…”
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DNA adducts formation and induction of apoptosis in rat liver epithelial 'stem-like' cells exposed to carcinogenic polycyclic aromatic hydrocarbons by Topinka, Jan, Marvanová, Sona, Vondrácek, Jan, Sevastyanova, Oksana, Nováková, Zuzana, Krcmár, Pavel, Pencíková, Katerina, Machala, Miroslav

“…The bipotent liver progenitor cells, so called oval cells, may participate at the early stages of hepatocarcinogenesis induced by chemical carcinogens. Unlike…”
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Toxic Effects of Methylated Benzo[a]pyrenes in Rat Liver Stem-Like Cells by Trilecová, Lenka, Krčková, Simona, Marvanová, Soňa, Pěnčíková, Kateřina, Krčmář, Pavel, Neča, Jiří, Hulinková, Petra, Pálková, Lenka, Ciganek, Miroslav, Milcová, Alena, Topinka, Jan, Vondráček, Jan, Machala, Miroslav

“…The methylated benzo[a]pyrenes (MeBaPs) are present at significant levels in the environment, especially in the sediments contaminated by petrogenic PAHs…”
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