Search Results - "Pence, Isaac J."

Single Particle Automated Raman Trapping Analysis of Breast Cancer Cell-Derived Extracellular Vesicles as Cancer Biomarkers by Penders, Jelle, Nagelkerke, Anika, Cunnane, Eoghan M, Pedersen, Simon V, Pence, Isaac J, Coombes, R. Charles, Stevens, Molly M

“…Extracellular vesicles (EVs) secreted by cancer cells provide an important insight into cancer biology and could be leveraged to enhance diagnostics and…”
Get full text

Surface enhanced Raman scattering artificial nose for high dimensionality fingerprinting by Kim, Nayoung, Thomas, Michael R., Bergholt, Mads S., Pence, Isaac J., Seong, Hyejeong, Charchar, Patrick, Todorova, Nevena, Nagelkerke, Anika, Belessiotis-Richards, Alexis, Payne, David J., Gelmi, Amy, Yarovsky, Irene, Stevens, Molly M.

“…Label-free surface-enhanced Raman spectroscopy (SERS) can interrogate systems by directly fingerprinting their components’ unique physicochemical properties…”
Get full text

Single Particle Automated Raman Trapping Analysis by Penders, Jelle, Pence, Isaac J., Horgan, Conor C., Bergholt, Mads S., Wood, Christopher S., Najer, Adrian, Kauscher, Ulrike, Nagelkerke, Anika, Stevens, Molly M.

“…Enabling concurrent, high throughput analysis of single nanoparticles would greatly increase the capacity to study size, composition and inter and intra…”
Get full text

Fast-acting and injectable cryoneurolysis device by Moradi Tuchayi, Sara, Wang, Ying, Khodorova, Alla, Pence, Isaac J., Stemmer-Rachamimov, Anat, Evans, Conor L., Anderson, R. Rox, Garibyan, Lilit

“…Cryoneurolysis is an opioid-sparing therapy for long-lasting and reversible reduction of pain. We developed a nerve-selective method for cryoneurolysis by…”
Get full text

In vivo Raman spectral analysis of impaired cervical remodeling in a mouse model of delayed parturition by O’Brien, Christine M., Herington, Jennifer L., Brown, Naoko, Pence, Isaac J., Paria, Bibhash C., Slaughter, James C., Reese, Jeff, Mahadevan-Jansen, Anita

“…Monitoring cervical structure and composition during pregnancy has high potential for prediction of preterm birth (PTB), a problem affecting 15 million…”
Get full text

Raman spectroscopy imaging reveals interplay between atherosclerosis and medial calcification in the human aorta by You, Amanda Y F, Bergholt, Mads S, St-Pierre, Jean-Philippe, Kit-Anan, Worrapong, Pence, Isaac J, Chester, Adrian H, Yacoub, Magdi H, Bertazzo, Sergio, Stevens, Molly M

“…Medial calcification in the human aorta accumulates during aging and is known to be aggravated in several diseases. Atherosclerosis, another major cause of…”
Get full text

Advances in vaginal bioengineering: Applications, techniques, and needs by Buchanan, Lily M., Domingo, Mari J.E., White, Shelby E., Vanoven, Triniti N., Karbasion, Niyousha, Bersi, Matthew R., Pence, Isaac J., Florian-Rodriguez, Maria, Miller, Kristin S.

Get full text

Glycosylated superparamagnetic nanoparticle gradients for osteochondral tissue engineering by Li, Chunching, Armstrong, James PK, Pence, Isaac J., Kit-Anan, Worrapong, Puetzer, Jennifer L., Correia Carreira, Sara, Moore, Axel C., Stevens, Molly M.

“…In developmental biology, gradients of bioactive signals direct the formation of structural transitions in tissue that are key to physiological function…”
Get full text

Buoyancy‐Driven Gradients for Biomaterial Fabrication and Tissue Engineering by Li, Chunching, Ouyang, Liliang, Pence, Isaac J., Moore, Axel C., Lin, Yiyang, Winter, Charles W., Armstrong, James P. K., Stevens, Molly M.

“…The controlled fabrication of gradient materials is becoming increasingly important as the next generation of tissue engineering seeks to produce inhomogeneous…”
Get full text

Determining topical product bioequivalence with stimulated Raman scattering microscopy by Iliopoulos, Fotis, Tu, Dandan, Pence, Isaac J., Li, Xiaolei, Ghosh, Priyanka, Luke, Markham C., Raney, Sam G., Rantou, Elena, Evans, Conor L.

“…Generic drugs are essential for affordable medicine and improving accessibility to treatments. Bioequivalence (BE) is typically demonstrated by assessing a…”
Get full text

Nanoscale Molecular Quantification of Stem Cell–Hydrogel Interactions by Maynard, Stephanie A, Gelmi, Amy, Skaalure, Stacey C, Pence, Isaac J, Lee-Reeves, Charlotte, Sero, Julia E, Whittaker, Thomas E, Stevens, Molly M

“…A common approach to tailoring synthetic hydrogels for regenerative medicine applications involves incorporating RGD cell adhesion peptides, yet assessing the…”
Get full text

Feature Selection and Rapid Characterization of Bloodstains on Different Substrates by Gautam, Rekha, Peoples, Deandra, Jansen, Kiana, O’Connor, Maggie, Thomas, Giju, Vanga, Sandeep, Pence, Isaac J., Mahadevan-Jansen, Anita

“…Establishing the precise timeline of a crime can be challenging as current analytical techniques used suffer from many limitations and are destructive to the…”
Get full text

Imaging and quantifying drug delivery in skin – Part 2: Fluorescence andvibrational spectroscopic imaging methods by Pena, Ana-Maria, Chen, Xueqin, Pence, Isaac J., Bornschlögl, Thomas, Jeong, Sinyoung, Grégoire, Sébastien, Luengo, Gustavo S., Hallegot, Philippe, Obeidy, Peyman, Feizpour, Amin, Chan, Kin F., Evans, Conor L.

“…Understanding the delivery and diffusion of topically-applied drugs on human skin is of paramount importance in both pharmaceutical and cosmetics research…”
Get full text

Spatiotemporal quantification of acoustic cell patterning using Voronoï tessellation by Armstrong, James P K, Maynard, Stephanie A, Pence, Isaac J, Franklin, Amanda C, Drinkwater, Bruce W, Stevens, Molly M

“…Acoustic patterning using ultrasound standing waves has recently emerged as a potent biotechnology enabling the remote generation of ordered cell systems. This…”
Get more information

Visualizing and quantifying antimicrobial drug distribution in tissue by Kuzma, Benjamin A., Pence, Isaac J., Greenfield, Daniel A., Ho, Alexander, Evans, Conor L.

“…[Display omitted] The biodistribution and pharmacokinetics of drugs are vital to the mechanistic understanding of their efficacy. Measuring antimicrobial drug…”
Get full text

Multi-window sparse spectral sampling stimulated Raman scattering microscopy by Pence, Isaac J., Kuzma, Benjamin A., Brinkmann, Maximilian, Hellwig, Tim, Evans, Conor L.

“…Stimulated Raman scattering (SRS) is a nondestructive and rapid technique for imaging of biological and clinical specimens with label-free chemical…”
Get full text

Duplex-Specific Nuclease-Amplified Detection of MicroRNA Using Compact Quantum Dot–DNA Conjugates by Wang, Ye, Howes, Philip D, Kim, Eunjung, Spicer, Christopher D, Thomas, Michael R, Lin, Yiyang, Crowder, Spencer W, Pence, Isaac J, Stevens, Molly M

“…Advances in nanotechnology have provided new opportunities for the design of next-generation nucleic acid biosensors and diagnostics. Indeed, combining…”
Get full text

Dual excitation wavelength system for combined fingerprint and high wavenumber Raman spectroscopy by Masson, Laura E, O'Brien, Christine M, Pence, Isaac J, Herington, Jennifer L, Reese, Jeff, van Leeuwen, Ton G, Mahadevan-Jansen, Anita

“…A fiber optic probe-based Raman spectroscopy system using a single laser module with two excitation wavelengths, at 680 and 785 nm, has been developed for…”
Get more information

Coupling Lipid Nanoparticle Structure and Automated Single‐Particle Composition Analysis to Design Phospholipase‐Responsive Nanocarriers by Barriga, Hanna M. G., Pence, Isaac J., Holme, Margaret N., Doutch, James J., Penders, Jelle, Nele, Valeria, Thomas, Michael R., Carroni, Marta, Stevens, Molly M.

“…Lipid nanoparticles (LNPs) are versatile structures with tunable physicochemical properties that are ideally suited as a platform for vaccine delivery and RNA…”
Get full text

Application driven assessment of probe designs for Raman spectroscopy by Pence, Isaac J, O'Brien, Christine M, Masson, Laura E, Mahadevan-Jansen, Anita

“…Raman spectroscopy has been utilized for the non-invasive, non-destructive assessment of tissue pathophysiology for a variety of applications largely through…”
Get full text