Search Results - "Penalva, Luiz Of"
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Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival
Published in Molecular cancer (21-08-2010)“…Musashi1 (Msi1) is a conserved RNA-binding protein that regulates the Notch and Wnt pathways, and serves as a stem cell marker in the breast and other tissues…”
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Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy
Published in BMC cancer (30-09-2008)“…Musashi1 (Msi1) is an RNA binding protein with a central role during nervous system development and stem cell maintenance. High levels of Msi1 have been…”
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RNA-binding proteins to assess gene expression states of co-cultivated cells in response to tumor cells
Published in Molecular cancer (07-09-2004)“…Tumors and complex tissues consist of mixtures of communicating cells that differ significantly in their gene expression status. In order to understand how…”
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A compendium of RNA-binding motifs for decoding gene regulation
Published in Nature (London) (11-07-2013)“…RNA-binding proteins are key regulators of gene expression, yet only a small fraction have been functionally characterized. Here we report a systematic…”
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miR‐124, ‐128, and ‐137 Orchestrate Neural Differentiation by Acting on Overlapping Gene Sets Containing a Highly Connected Transcription Factor Network
Published in Stem cells (Dayton, Ohio) (01-01-2016)“…The ventricular‐subventricular zone harbors neural stem cells (NSCs) that can differentiate into neurons, astrocytes, and oligodendrocytes. This process…”
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Antagonism between the RNA-binding protein Musashi1 and miR-137 and its potential impact on neurogenesis and glioblastoma development
Published in RNA (Cambridge) (01-07-2019)“…RNA-binding proteins (RBPs) and miRNAs are critical gene expression regulators that interact with one another in cooperative and antagonistic fashions. We…”
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Before It Gets Started : Regulating Translation at the 5′ UTR
Published in Comparative and functional genomics (01-01-2012)“…Translation regulation plays important roles in both normal physiological conditions and diseases states. This regulation requires cis-regulatory elements…”
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IGF2BP3 Modulates the Interaction of Invasion-Associated Transcripts with RISC
Published in Cell reports (Cambridge) (31-05-2016)“…Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) expression correlates with malignancy, but its role(s) in pathogenesis remains enigmatic. We…”
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The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells
Published in Molecular cancer research (01-01-2012)“…Musashi1 (Msi1) is an evolutionarily conserved RNA-binding protein (RBP) that has profound implications in cellular processes such as stem cell maintenance,…”
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Genomic Analyses of Musashi1 Downstream Targets Show a Strong Association with Cancer-related Processes
Published in The Journal of biological chemistry (01-05-2009)“…Musashi1 (Msi1) is a highly conserved RNA-binding protein with pivotal functions in stem cell maintenance, nervous system development, and tumorigenesis…”
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